長崎大学 高度感染症研究センター 新興ウイルス研究分野/熱帯医学研究所　新興感染症学分野

アジア・アフリカにおける新興ウイルス感染症研究モデル拠点の形成 SATREPS ガボン共和国におけるウイルス感染症プロジェクト
長崎大学熱帯医学研究所
新興感染症学分野
〒852-8523
長崎県長崎市坂本1-12-4
TEL：095-819-7851
FAX：095-819-7851
  • 長崎大学
  • 長崎大学大学院 医歯薬学総合研究科
  • 長崎大学 熱帯医学研究所（熱研）
  • Tropical Medicine and Health

研究業績

原著論文

  1. Takagi Y, Sudo K, Yamaguchi S, Urata S, Ohno T, Hirose S, Matsumoto K, Kuramoto T, Serikawa T, Yasuda J, Ikutani M, Nakae S. Characterization of novel, severely immunodeficient
    PrkdcΔex57/Δex57 mice. Biochem Biophys Res Commun, 2023;678:193-199.
  2. Abe H, Ushijima Y, Bikangui R, Ondo GN, Pemba CM, Zadeh VR, Mpingabo PI, Ueda H, Agnandji ST, Lell B, Yasuda J. Genetic Diversity of Hepatitis B and C Viruses Revealed by Continuous Surveillance from 2015 to 2021 in Gabon, Central Africa. Microorganisms, 2023;11(8):2046.
  3. Kawasaki Y, Abe H, Yasuda J. Comparison of genome replication fidelity between SARS-CoV-2 and influenza A virus in cell culture. Sci Rep, 2023;13(1):13105.
  4. Yoshikawa R, Kawakami M, Yasuda J. The NSs protein of severe fever with thrombocytopenia syndrome virus differentially inhibits the type 1 interferon response among animal species. J Biol Chem, 2023;299(6):104819.
  5. Urata S, Yoshikawa R, Yasuda J. Calcium Influx Regulates the Replication of Several Negative-Strand RNA Viruses Including Severe Fever with Thrombocytopenia Syndrome Virus. J Virol, 2023;97(3):e0001523.
  6. Afowowe TO, Sakurai Y, Urata S, Zadeh VR, Yasuda J. Topoisomerase II as a Novel Antiviral Target against Panarenaviral Diseases. Viruses, 2022;15(1):105.
  7. Urata S, Yamaguchi S, Nambu A, Sudo K, Nakae S, Yasuda J. The roles of BST-2 in murine B cell development and on virus propagation. Microbiol Immunol, 2023;67(3):105-113.
  8. Abe H, Ushijima Y, Bikangui R, Ondo GN, Moure A, Yali-Assy-Oyamli Y, Yoshikawa R, Lell B, Adegnika AA, Yasuda J. Long-term validation of a reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay for the rapid detection of SARS-CoV-2 from March 2020 to October 2021 in Central Africa, Gabon. PLoS Negl Trop Dis, 2022;16(12):e0010964.
  9. Ozeki T, Abe H, Ushijima Y, Nze-Nkogue C, Akomo-Okoue EF, Ella GWE, Koumba LBM, Nso BCBB, Mintsa-Nguema R, Makouloutou-Nzassi P, Makanga BK, Nguelet FLM, Ondo GN, Mbadinga MJVM, Igasaki Y, Okada S, Hirano M, Yoshii K, Lell B, Bonney LC, Hewson R, Kurosaki Y, Yasuda J. Identification of novel orthonairoviruses from rodents and shrews in Gabon, Central Africa. J Gen Virol, 2022;103(10).
  10. Ushijima Y, Abe H, Mbadinga MJVM, Ondo GN, Bikangui R, Agnandji ST, Lell B, Yasuda J. Re-emergence of dengue, chikungunya, and Zika viruses in 2021 after a 10-year gap in Gabon. IJID Reg, 2022;5:68-71.
  11. Tegally H, … Abe H, … Yasuda J, … Wilkinson E. The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance. Science, 2022;378(6615):eabq5358.
  12. Zadeh VR, Afowowe TO, Abe H, Urata S, Yasuda J. Potential and action mechanism of favipiravir as an antiviral against Junin virus.
    PLoS Pathog. 2022 11;18(7):e1010689.
  13. Ngwe Tun MM, Sakura T, Sakurai Y, Kurosaki Y, Inaoka DK, Shinoda N, Smith C, Yasuda J, Morita K, Kita K. 5-aminolevulinic acid antiviral efficacy against SARS-CoV-2 Omicron Variant in vitro. Trop Med Health. 2022. 27;50(1):30.
  14. Abe H, Ushijima Y, Bikangui R, Nguema Ondo G, LellB, Adegnika AA, Yasuda J. Delays in the arrival of the waves ofCOVID-19: comparison between Gabon and the African continent. Lancet Microbe. 2022 ;3(7):e476.
  15. Hirano M, Sakurai Y, Urata S, Kurosaki Y, Yasuda J, Yoshii K. A screen of FDA-approved drugs with minigenome identified tigecycline as an antiviral targeting nucleoprotein of Crimean-Congo hemorrhagic fever virus. Antiviral Res. 2022;200:105276.
  16. Urata S, Omotuyi OI, Izumisawa A, Ishikawa T, Mizuta S, Sakurai Y, Mizutani T, Ueda H, Tanaka Y, Yasuda J. Identification of novel chemical compounds targeting filovirus VP40-mediated particle production. Antiviral Res. 2022;199:105267.
  17. Masuda A, Lee JM, Miyata T, Mon H, Sato K, Oyama K, Sakurai Y, Yasuda J, Takahashi D, Ueda T, Kato Y, Nishida M, Karasaki N, Kakino K, Ebihara T, Nagasato T, Hino M, Nakashima A, Suzuki K, Tonooka Y, Tanaka M, Moriyama T, Nakatake H, Fujita R, Kusakabe T. Optimization of SARS-CoV-2 Spike Protein Expression in the Silkworm and Induction of Efficient Protective Immunity by Inoculation With Alum Adjuvants. Front Immunol. 2022;12:803647
  18. Moni BM, Sakurai Y, Yasuda J. Ebola Virus GP Activates Endothelial Cells via Host Cytoskeletal Signaling Factors. Viruses. 2022;14(1):142.
  19. Abe H, Ushijima Y, Amano M, Sakurai Y, Yoshikawa R, Kinoshita T, Kurosaki Y, Yanagihara K, Izumikawa K, Morita K, Kohno S, Yasuda J. Unique Evolution of SARS-CoV-2 in the Second Large Cruise Ship Cluster in Japan. Microorganisms. 2022;10(1):99.
  20. Ngwe Tun MM, Sakura T, Sakurai Y, Kurosaki Y, Inaoka DK, Shioda N, Yasuda J, Kita K, Morita K. Antiviral activity of 5-aminolevulinic acid against variants of severe acute respiratory syndrome coronavirus 2. Trop Med Health. 2022;50(1):6.
  21. Kinoshita T, Watanabe K, Sakurai Y, Nishi K, Yoshikawa R, Yasuda J. Co-infection of SARS-CoV-2 and influenza virus causes more severe and prolonged pneumonia in hamsters. Sci Rep. 2021;11(1):21259.
  22. Wilkinson E, …Abe H, ..Yasuda J, et al. (total 303 authors): A year of genomic surveillance reveals how the SARS-CoV-2 pandemic unfolded in Africa. Science. 2021;374(6566):423-431.
  23. Maeda H, Sando E, Toizumi M, Arima Y, Shimada T, Tanaka T, Tashiro M, Fujita A, Yanagihara K, Takayama H, Yasuda I, Kawachi N, Kohayagawa Y, Hasegawa M, Motomura K, Fujita R, Nakata K, Yasuda J, Morita K, Kohno S, Izumikawa K, Suzuki M, Morimoto K. Epidemiology of Coronavirus Disease Outbreak among Crewmembers on Cruise Ship, Nagasaki City, Japan, April 2020. Emerg Infect Dis. 2021;27(9):2251-2260.
  24. Abe H*, Ushijima Y*, Bikangui R, Zoa-Assoumou S, Ondo GN, Manouana GP, More A, Skarwan E, Yali-Assy-Oyamli Y, Ndeboko B, Myrabelle Avome Houechenou R, Djoba Siawaya JF, Lell B, Adegnika AA, Yasuda J. Unrecognized introduction of SARS-CoV-2 variants of concern to Central Africa: Import and local transmission of B.1.1.7 in Gabon in the very early stage of the variant spread to the African continent. J Med Virol. 2021 ;93(10):6054-6058.
    * These authors contributed equally to this work.
  25. Zoa-Assoumou S, Ndeboko B, Manouana GP, Houechenou RMA, Bikangui R, Mveang-Nzoghe A, Ondo GN, Mbongo-Kama E, Lell B, Abe H, Ushijima Y, Antchouey AM, Yasuda J, Adegnika AA, Siawaya JFD. SARS-CoV-2 emerging variants in Africa: view from Gabon.Lancet Microbe. 2021;2(8):e349.
  26. Ota K, Yanagihara K, Sasaki D, Kaku N, Uno N, Sakamoto K, Kosai K, Miyazaki T, Hasegawa H, Fujita A, Tashiro M, Tanaka T, Izumikawa K, Ariyoshi K, Mukae H, Yasuda J, Morita K, Kohno S. Detection of SARS-CoV-2 using qRT-PCR in saliva obtained from asymptomatic or mild COVID-19 patients, comparative analysis with matched nasopharyngeal samples. PLoS One. 2021;10;16(6):e0252964.
  27. Urata S, Yasuda J, Iwasaki M.Loperamide Inhibits Replication of Severe Fever with Thrombocytopenia Syndrome Virus. Viruses. 2021;10;13(5):869.
  28. Imamura K*, Sakurai Y*, Enami T, Shibukawa R, Nishi Y, Ohta A, Shu T, Kawaguchi J, Okada S, Hoenen T, Yasuda J, Inoue H. iPSC screening for drug repurposing identifies anti-RNA virus agents modulating host cell susceptibility. FEBS Open Bio. 2021;11(5):1452-1464.
    * These authors contributed equally to this work.
  29. Ushijima Y, Abe H, Nguema Ondo G, Bikangui R, Massinga Loembé M, Zadeh VR, Essimengane JGE, Mbouna AVN, Bache EB, Agnandji ST, Lell B, Yasuda J. Surveillance of the major pathogenic arboviruses of public health concern in Gabon, Central Africa: increased risk of West Nile virus and dengue virus infections. BMC Infect Dis. 2021;21(1):265.
  30. Ushijima Y, Abe H, Ozeki T, Ondo GN, Mbadinga MJVM, Bikangui R, Nze-Nkogue C, Akomo-Okoue EF, Ella GWE, Koumba LBM, Nso BCBB, Mintsa-Nguema R, Makouloutou-Nzassi P, Makanga BK, Nguelet FLM, Zadeh VR, Urata S, Mbouna AVN, Massinga-Loembe M, Agnandji ST, Lell B, Yasuda J. Identification of potential novel hosts and the risk of infection with lymphocytic choriomeningitis virus in humans in Gabon, Central Africa. Int J Infect Dis. 2021; 105:452-459.
  31. Sakurai Y, Ngwe Tun MM, Kurosaki Y, Sakura T, Inaoka DK, Fujine K, Kita K, Morita K, Yasuda J. 5-amino levulinic acid inhibits SARS-CoV-2 infection in vitro. Biochem Biophys Res Commun. 2021;545:203-207.
  32. Mizutani T, Ohba Y, Mizuta S, Yasuda J, Urata S. An Antiviral Drug Screening Platform with a FRET Biosensor for Measurement of Arenavirus Z Assembly.Cell Struct Funct. 2020;45(2):155-163.
  33. Mpingabo PI, Urata S, Yasuda J. Analysis of the Cell Type-Dependence on the Arenavirus Z-Mediated Virus-Like Particle Production. Front Microbiol. 2020;11:562814.
  34. Zadeh VR, Urata S, Sakaguchi M, Yasuda J. Human BST-2/tetherin inhibits Junin virus release from host cells and its inhibition is partially counteracted by viral nucleoprotein. J Gen Virol. 2020;101(6):573-586.
  35. Primadharsini PP, Nagashima S, Takahashi M, Kobayashi T, Nishiyama T, Nishizawa T, Yasuda J, Mulyanto, Okamoto H. Multivesicular body sorting and the exosomal pathway are required for the release of rat hepatitis E virus from infected cells. Virus Res. 2020;278:197868.
  36. Abe H, Ushijima Y, Bikangui R, Ondo GN, Zadeh VR, Pemba CM, Mpingabo PI, Igasaki Y, de Vries SG, Grobusch MP, Loembe MM, Agnandji ST, Lell B, Yasuda J. First evidence for continuous circulation of hepatitis A virus subgenotype IIA in Central Africa. J Viral Hepat. 2020;27(11):1234-1242.
  37. Yoshikawa R*, Abe H*, Igasaki Y, Negishi S, Goto H, Yasuda J. Development and evaluation of a rapid and simple diagnostic assay for COVID-19 based on loop-mediated isothermal amplification. PLoS Negl Trop Dis. 2020;14(11):e0008855.
    * These authors contributed equally to this work.
  38. Abe H, Ushijima Y, Bikangui R, Loembe MM, Agnandji ST, de Vries SG, Grobusch MP, Lell B, Yasuda J. Ongoing evolution of hepatitis B virus during viremia in patients with febrile in Central Africa. J Med Virol. 2020;92(2):251-256.
  39. Abe H, Ushijima Y, Loembe MM, Bikangui R, Nguema-Ondo G, Mpingabo PI, Zadeh VR, Pemba CM, Kurosaki Y, Igasaki Y, de Vries SG, Grobusch MP, Agnandji ST, Lell B, Yasuda J. Re-emergence of dengue virus serotype 3 infections in Gabon in 2016-2017, and evidence for the risk of repeated dengue virus infections. Int J Infect Dis. 2020;91:129-136.
  40. Urata S, Ishikawa T, Yasuda J.,Roles of YIGL sequence of Ebola virus VP40 on genome replication and particle production. J Gen Virol. 2019;100(7):1099-1111.
  41. Pemba CM, Kurosaki Y, Yoshikawa R, Oloniniyi OK, Urata S, Sueyoshi M, Zadeh VR, Nwafor I, Iroezindu MO, Ajayi NA, Chukwubike CM, Chika-Igwenyi NM, Ndu AC, Nwidi DU, Maehira Y, Unigwe US, Ojide CK, Onwe EO, Yasuda J.., Development of an RT-LAMP assay for the detection of Lassa viruses in southeast and south-central Nigeria., J Virol Methods., vol. 269, 30-37, 2019
  42. Yoshikawa R*, Sakabe S*, Urata S, Yasuda J.., Species-Specific Pathogenicity of Severe Fever with Thrombocytopenia Syndrome Virus Is Determined by Anti-STAT2 Activity of NSs. J Virol., vol. 93 (10), 2019.
    * These authors contributed equally to this work.
  43. Oloniniyi OK, Unigwe US, Okada S, Kimura M, Koyano S, Miyazaki Y, Iroezindu MO, Ajayi NA, Chukwubike CM, Chika-Igwenyi NM, Ndu AC, Nwidi DU, Abe H, Urata S, Kurosaki Y, Yasuda J., Genetic characterization of Lassa virus strains isolated from 2012 to 2016 in southeastern Nigeria., PLoS Negl Trop Dis. vol. 12(11), e0006971, 2018
  44. Arima A, Harlisa IH, Yoshida T, Tsutsui M, Tanaka M, Yokota K, Tonomura W, Yasuda J., Taniguchi M, Washio T, Okochi M, Kawai T., Identifying Single Viruses Using Biorecognition Solid-State Nanopores.,J Am Chem Soc., vol. 140 (48), 16834-16841, 2018
  45. Urata S, Kenyon E, Nayak D, Cubitt B, Kurosaki Y, Yasuda J, de la Torre JC, McGavern DB., BST-2 controls T cell proliferation and exhaustion by shaping the early distribution of a persistent viral infection. PLoS Pathog., 14(7):e1007172, 2018
  46. Urata S, Uno Y, Kurosaki Y, Yasuda J., The cholesterol, fatty acid and triglyceride synthesis pathways regulated by site 1 protease (S1P) are required for efficient replication of severe fever with thrombocytopenia syndrome virus. Biochem Biophys Res Commun., 503(2):631-636, 2018
  47. Kurosaki Y.., Ueda MT., Nakano Y., Yasuda J.., Koyanagi Y., Sato K., Nakagawa S.. Different effects of two mutations on the infectivity of Ebola virus glycoprotein in nine mammalian species.J Gen Virol., 99(2):181-186, 2018
  48. Watanabe K, Ishikawa T, Otaki H, Mizuta S, Hamada T, Nakagaki T, Ishibashi D, Urata S, Yasuda J, Tanaka Y, Nishida N.,Structure-based drug discovery for combating influenza virus by targeting the PA-PB1 interaction.,Sci Rep. vol. 7(1),9500, 2017
  49. Kurosaki Y.., Martins D.B.G., Kimura M., Catena A.D.S., Borba M.A.C.S.M., Mattos S.D.S., Abe H., Yoshikawa R., de Lima Filho J.L., *Yasuda J.. Development and evaluation of a rapid molecular diagnostic test for Zika virus infection by reverse transcription loop-mediated isothermal amplification. Sci. Rep., vol.7(1),13503,2017
  50. Sakurai T, Nakagawa S, Bai H, Bai R, Kusama K, Ideta A, Aoyagi Y, Kaneko K, IgYasuda J. K, Yasuda J, Miyazawa T, Imakawa K., Novel endogenous retrovirus-derived transcript expressed in the bovine placenta is regulated by WNT signaling., Biochem J., vol. 474(20), 3499-3512, 2017
  51. Oloniniyi OK, Kurosaki Y, Miyamoto H, Takada A, Yasuda J., Rapid detection of all known ebolavirus species by reverse transcription-loop-mediated isothermal amplification (RT-LAMP).J Virol Methods. vol.246, 8-14, 2017
  52. Kusama K, Bai R, Nakamura K, Okada S, Yasuda J, Imakawa K., Endometrial factors similarly induced by IFNT2 and IFNTc1 through transcription factor FOXS1. PLoS One. vol. 12(2), e0171858, 2017
  53. Ueda MT, Kurosaki Y, Izumi T, Nakano Y, Oloniniyi OK, Yasuda J, Koyanagi Y, Sato K, Nakagawa S., Functional mutations in spike glycoprotein of Zaire ebolavirus associated with an increase in infection efficiency.,Genes Cells. vol. 22(2),148-159, 2017
  54. Howson E.L.A., Kurosaki Y.., Yasuda J.., Takahashi M., Goto H., Gray A.R., Mioulet V., King D.P., Fowler V.L.. Defining the relative performance of isothermal assays that can be used for rapid and sensitive detection of foot-and-mouth disease virus. J. Virol. Methods. vol.249, 102-110, 2017
  55. Maehira Y., Jakimo A.L., Saito T., Kurosaki Y., Yasuda J., Tarui M., Malvy D.J.M, and Takeuchi T.: Responding to ever-changing epidemiological dynamics of Ebola virus disease. BMJ Global Health, vol.14 (1), 776-786, 2017
  56. Kurosaki Y., Okada S., Nakamae S., and *Yasuda J.: A loop-mediated isothermal amplification assay for rapid and sensitive detection of bovine papular stomatitis virus. Journal of Virological Methods, 238, 42-47, 2016.
  57. Uchida L., Urata S., Ulanday G.E., Takamatsu Y., Yasuda J., Morita K., and Hayasaka D.: Suppressive Effects of the Site 1 Protease (S1P) Inhibitor, PF-429242, on Dengue Virus Propagation. Viruses, 8 (2), E46 (1-12), 2016.
  58. Shimada S., Aoki K., Nabeshima T., Fuxun Y., Kurosaki Y., Shiogama K., Onouchi T., Sakaguchi M., Fuchigami T., Ono H., Nishi K., Posadas-Herrera G., Uchida L., Takamatsu Y., Yasuda J., Tsutsumi Y., Fujita H., Morita K., and Hayasaka D.: Tofla virus: A newly identified Nairovirus of the Crimean-Congo hemorrhagic fever group isolated from ticks in Japan. Scientific Reports, 6:20213 (1-11), 2016.
  59. Kurosaki Y, Magassouba N, Bah HA, Soropogui B, Doré A, Kourouma F, Cherif MS, Keita S, Yasuda J., Development of a Reverse Transcription Loop-Mediated Isothermal Amplification Test for Ebola Virus Surveillance in Remote Areas in Guinea. J Infect Dis. 2016;214(suppl 3):S229-S233.
  60. Kurosaki Y, Okada S, Nakamae S, Yasuda J. Loop-mediated isothermal amplification assay for rapid and sensitive detection of bovine papular stomatitis virus. J Virol Methods. 2016;238:42-47.
  61. Kurosaki Y, Magassouba N, Oloniniyi OK, Cherif MS, Sakabe S, Takada A, Hirayama K, Yasuda J.:Development and Evaluation of Reverse Transcription-Loop-Mediated Isothermal Amplification (RT-LAMP) Assay Coupled with a Portable Device for Rapid Diagnosis of Ebola Virus Disease in Guinea. PLoS Negl Trop Dis. 2016 Feb 22;10(2):e0004472
  62. Urata S., Weyer J., Storm N., Miyazaki Y., van Vuren P.J., Paweska J.T., and Yasuda J.: Analysis of assembly and budding of Lujo virus. Journal of Virology 90(6):3257-61, 2016
  63. Chisato N. Yasuda J.: Roles of the three L-domains in β-retrovirus budding. Microbiology and Immunology. vol.59 (9), 545-54, 2015
  64. Urata S., Yasuda J.: Cis- and cell type-dependent trans-requirements for Lassa virus-like particle production. J Gen Virol. vol.96 (Pt7) 1626-35, 2015
  65. Yoshikawa R., Miyaho RN., Hashimoto A., Abe M., Yasuda J., Miyazawa T.: Suppression of production of baboon endogenous virus by dominant negative mutants of cellular factors involved in multivesicular body sorting pathway. Virus Res. vol. 196, 128-134, 2015
  66. Abe M., Fukuma A., Yoshikawa R., Miyazawa T., Yasuda J.: Inhibition of budding/release of porcine endogenous retrovirus. Microbiol Immunol. vol. 58 (8): 432-8, 2014
  67. Shimode S., Nakaoka R., Hoshino S., Abe M., Shogen H., Yasuda J., Miyazawa T.; Identification of cellular factors required for the budding of koala retrovirus. Microbiol. Immunol. vol. 57 (7), 543-6, 2013
  68. Shojima. T., Nakaoka, R., Hoshino, S., Abe, M., Shogen, H., Yasuda, J.., and Miyazawa, T.: Construction and characterization of an infectious molecular clone of koala retrovirus. Journal of Virology, 87(9), 5081-5088, 2013.
  69. Fukuma, A., Yoshikawa, R., Miyazawa, T., and *Yasuda, J.: A new approach to establish a cell line with reduced risk of endogenous retroviruses. PLoS One, 8(4), e61530 (1-5), 2013.
  70. Imakawa, K., Yasuda, J., Kobayashi, T., and Miyazawa, T.: Changes in Gene Expression Associated with Conceptus Implantation to the Maternal Endometrium. Journal of Mammalian Ova Research, 30, 2013. 30, 2013.
  71. Okada J., Horiuchi1, H., Hashimoto, K., Hirosawa, D., Kurosaki, Y., Kawamoto, K, Yasuda, J., Makino, S., Gemma, N., and Nikaido, M.: Mobile Automatic Detection System for Bacillus anthracis using Electrochemical DNA Chip. Journal of Biosensors and Bioelectronics, 3, 126, 2012.
  72. Takeda E., Nakagawa S., Nakaya Y., Tanaka A., Miyazawa T., Yasuda, J.: Identification and Functional Analysis of Three Isoforms of Bovine BST-2. PLoS one, 7, e41483, 2012.
  73. Urata S., Nhi N., de la Torre J. C.: The PI3K/Akt pathway contributes to Arenavirus budding. Journal of Virology, 86 (8), 4578-85, 2012.
  74. Fukuma A., Abe M., Urata S., Yoshikawa R., Morikawa Y., Miyazawa T., Yasuda, J.: Viral and cellular requirements for the budding of Feline Endogenous Retrovirus RD-114. Virology Journal, 8 (1), 540, 2011.
  75. Yoshikawa R., Yasuda, J., Kobayashi T., Miyazawa T.: Canine ASCT1 and ASCT2 are functional receptors for RD-114 virus in dogs. Journal of General Virology, 93, 603-7, 2012.
  76. Nagashima, S., Takahashi, M., Jirintai, S., Tanaka, T., Nishizawa, T., Yasuda, J., Okamoto, H.: Tsg101 and the vacuolar protein sorting pathway are required for release of hepatitis E virions. Journal of General Virology, 92, 2838-2848, 2011.
  77. Kim, B-G., Lee, J-H., Yasuda, J., Ryoo, H-M., and Cho, J-Y.: Phospho-Smad1 modulation by Nedd4 E3 ligase in BMP/TGF signaling. Journal of Bone and Mineral Research, 26 (7), 1411-24, 2011.
  78. Fukuma, A., Abe, M., Morikawa, Y., Miyazawa, T., and *Yasuda, J.: Cloning and Characterization of the Antiviral Activity of Feline Tetherin/BST-2. PLoS One, 6, e18247 (1-6), 2011.
  79. Nakaya, Y., Hoshino, S., Yasuda, J., and Miyazawa, T.: Mapping of a neutralizing epitope in the surface envelope protein of porcine endogenous retrovirus subgroup B. Journal of General Virology,92, 940-944, 2011.
  80. Fujinami, Y., Kikkawa, H.S., Kurosaki, Y., Sakurada, K., Yoshino, M., and Yasuda, J.: Rapid discrimination of Legionella by matrix-assisted laser desorption ionization time-of-flight mass spectrometry. Microbiol Res., 166, 77-86, 2011.
  81. Popkin, DL., Teijaro. JR., Sullivan, BM., Urata, S., Rutschmann, S., de la Torre, JC., Kunz, S., Beutler, B., Oldstone, M.: Hypomorphic mutation in the site-1 protease mbtps1 endows resistance to persistent viral infection in a cell-specific manner. Cell Host Microbe, 9 (3), 212-22, 2011
  82. Nakaya,Y., Shojima, T., Yasuda, J., Imakawa, K., and Miyazawa, T.: Epigenetic regulation on the 5'-proximal CpG island of human porcine endogenous retrovirus subgroup A receptor 2/GPR172B. Microbes Infect., 13, 49-57, 2011.
  83. Fukuma, A., Kurosaki, Y., Morikawa, Y., Grolla, A., Feldmann, H., and *Yasuda, J.: Rapid detection of Lassa virus by reverse transcription – loop-mediated isothermal amplification. Microbiology and Immunology, 55, 44-50, 2011.
  84. Urata, S., Yun, N., Pasquato, A., Paessler, S., Kunz, S., de la Torre, JC.: Antiviral activity of a small-molecule inhibitor of arenavirus glycoprotein processing by the cellular site 1 protease. Journal of Virology, 85 (2), 795-803, 2011
  85. Kurosaki, Y., Grolla, A., Fukuma, A., Feldmann, H., and *Yasuda, J.: Development and evaluation of the simple diagnostic assay for Marburgvirus using reverse transcription-loop-mediated isothermal amplification method. Journal of Clinical Microbiology, 48, 2330-2336, 2010.
  86. Nakaya,Y., Shojima, T., Yasuda, J., and Miyazawa, T.: Unusual permeability of porcine endogenous retrovirus subgroup A through membrane filters. J. Vet. Med. Sci., 72, 67-71, 2010.
  87. Urata, S., and *Yasuda, J.: Regulation of Marburg virus budding by Nedd4.1; a different WW domain of Nedd4.1 is critical for the binding to Marburg and Ebola virus VP40. Journal of General Virology, 91, 228-234, 2010.
  88. Urata, S., Yasuda, J., and de la Torre, J.C.: The Z protein of the New world arenavirus Tacaribe virus has bona fide budding activity that does not depend on known late domain motifs. Journal of Virology, 83 (23), 12651-12655, 2009.
  89. Sakuma, T., Sakurai, A., and *Yasuda, J.: Dimerization of tetherin is not essential for its antiviral activity against Lassa and Marburg viruses. PLoS One, 4, e6934, 2009.
  90. Kurosaki, Y., Sakuma, T., Fukuma, A., Fujinami, Y., Kamo, N., Makino, S., and *Yasuda, J.: A Simple and Sensitive Method for Detection of Bacillus anthracis by Loop-Mediated Isothermal Amplification. Journal of Applied Microbiology, 107, 1947-1956, 2009.
  91. Sakuma, T., Kurosaki, Y., Fujinami, Y., Takizawa, T., and *Yasuda, J.: Rapid and simple detection of Clostridium botulinum types A and B by loop-mediated isothermal amplification. Journal of Applied Microbiology, 106, 1252-1259, 2009.
  92. Sakuma, T., Noda, T., Urata, S., Kawaoka, Y., and *Yasuda, J.: Inhibition of Lassa and Marburg virus production by Tetherin. Journal of Virology, 83 (5), 2382-2385, 2009.
  93. Kikkawa, S. H., Ueda, T., Suzuki, S., and *Yasuda, J.: Characterization of the catalytic activity of the γ-phage lysin, PlyG, specific for Bacillus anthracis. FEMS Microbiology Letters, 286, 236-240, 2008.
  94. Kikkawa, H., Fujinami, Y., Suzuki, S., and *Yasuda, J.: Identification of the amino acid residues critical for specific binding of the bacteriolytic enzyme of γ-phage, PlyG, to Bacillus anthracis. B.B.R.C., 363, 531-535, 2007.
  95. Urata, S., Yokosawa, H., and *Yasuda, J.: Regulation of HTLV-1 Gag budding by Vps4A, Vps4B, and AIP1/Alix. Virology Journal, 4, 66 (1-5), 2007.
  96. Urata, S., Noda, T., Kawaoka, Y., Morikawa, S., Yokosawa, H., and *Yasuda, J.: Interaction of Tsg101 with Marburg virus VP40 depends on the PPPY motif, but not the PT/SAP motif as in the case of Ebola virus, and Tsg101 plays a critical role in the budding of Marburg virus-like particles induced by VP40, NP, and GP. Journal of Virology, 81 (9), 4895-4899, 2007.
  97. Kurosaki, Y., Takada, A., Ebihara, H., Grolla, A., Kamo, N., Feldmann,　H., Kawaoka, Y., and *Yasuda, J.: Rapid and Simple Detection of Ebola Virus by Reverse Transcription-Loop-Mediated Isothermal Amplification. Journal of Virological Methods, 141, 78-83, 2007.
  98. Fujinami, Y., Hirai, Y., Sakai, I., Yoshino, M., and *Yasuda, J.: Sensitive detection of Bacillus anthracis using a binding protein originating from γ-phage. Microbiology and Immunology, 51, 163-169, 2007.
  99. Tsurutani, N., Yasuda, J., Yamamoto, N., Choi, B-I., Kadoki, M., and Iwakura, Y.: Nuclear Import of the Pre-integration Complex Is Blocked upon Infection by HIV-1 in Mouse Cells. Journal of Virology, 81, 677-688, 2007.
  100. Horii, M., Shibata, H., Kobayashi, R., Katoh, K., Yorikawa, C., Yasuda, J., and Maki, M.: CHMP7, a novel ESCRT-III-related protein, associates with CHMP4b and functions in the endosomal sorting pathway. Biochemical Journal, 400, 23-32, 2006.
  101. Urata, S., Noda, T., Kawaoka, Y., Yokosawa, H., and *Yasuda, J.: Cellular factors required for Lassa virus budding. Journal of Virology, 80 (8), 4191-4195, 2006.
  102. Katoh, K., Suzuki, H., Terasawa, Y., Mizuno, T., Yasuda, J., Shibata, H., and Maki, M. The penta-EF-hand protein ALG-2 directly interacts with the ESCRT-I component TSG101 and Ca2+-dependently colocalizes to aberrant endosomes with dominant-negative AAA ATPase SKD1/Vps4B. Biochemical Journal, 391, 677-85, 2005, 2005.
  103. Sakurai, A., Yasuda, J., Takano, H., Tanaka, Y., Hatakeyama, M., and Shida, H.: Regulation of human T-cell leukemia virus type-1 (HTLV-1) budding by ubiquitin ligase Nedd4. Microbes and Infection, 6, 150-156, 2004.
  104. *Yasuda, J., Nakao, M., Kawaoka, Y., and Shida, H.: Nedd4 regulates egress of Ebola virus from host cells. Journal of Virology, 77, 9987-9992, 2003.
  105. Tanaka, J., Ishida, T., Choi, B.-I., Yasuda, J., Watanabe, T., and Iwakura, Y.: Latent HIV-1 reactivation in transgenic mice requires cell cycle-dependent demethylation of CREB/ATF sites in the LTR. AIDS, 17, 167-175, 2003.
  106. Yasuda, J., Hunter, E., Nakao, M., and Shida, H.: Functional involvement of a novel Nedd4-like ubiquitin ligase on retrovirus budding. EMBO Reports, 3, 636-640, 2002.
  107. Yokoyama, H., Yasuda, J., Okamoto, H., and Iwakura, Y.: Development of nephritic syndrome with severe ascites in mice transgenic for the TT virus ORF1 gene. Journal of General Virology, 83, 141-150, 2002.
  108. Yasuda, J., Miyao, T., Kamata, M., Aida, Y., and Iwakura, Y.: T cell apoptosis causes peripheral T cell depletion in mice transgenic for the HIV-1 vpr gene. Virology, 285, 181-192, 2001.
  109. Tanaka, J., Ozaki, H., Yasuda, J., Horai, R., Tagawa, Y., Asano, M., Imai, M., Sekikawa, K., Kopf, M., and Iwakura, Y.: LPS-induced HIV-1 expression in transgenic mice is mediated by TNF-a and IL-1, but not by IFN-g nor IL-6. AIDS, 14, 1299-1307, 2000.
  110. Yasuda, J., and Hunter, E.: Role of Matrix protein in the type-D retrovirus replication cycle: Importance of the arginine residue at position 55. Virology, 268, 533-538, 2000.
  111. Ito, T., Kawaoka, Y., Kameda, C., Yasuda, J., Kida, H., and Otsuki,K.: Differences in receptor specificity between Newcastle disease viruses originating from chickens and waterfowl. J. Vet. Med. Sci., 61, 951-953, 1999.
  112. Ito, T., Kawaoka, Y., Ohira, M., Takakuwa, H., Yasuda, J., Kida, H., and Otsuki, K.: Replacement of internal protein genes, with the exception of the matrix, in equine 1 viruses by equine 2 influenza virus genes during evolution in nature. J. Vet. Med. Sci., 61, 987-989, 1999.
  113. Yasuda, J., and Hunter, E.: A proline-rich motif (PPPY) in the Gag polyprotein of Mason-Pfizer monkey virus plays a maturation-independent role in virion release. Journal of Virology, 72, 4095-4103, 1998.
  114. Yasuda, J., Bucher, D., and Ishihama, A.: Growth control of influenza A virus by M1 protein: Analysis of transfectant viruses carrying the chimeric M gene. Journal of Virology, 68, 8141-8146, 1994.
  115. Kida, H., Ito, T., Yasuda, J., Shimizu, Y., Itakura, C., Shortridge, K.F., Kawaoka, Y., and Webster, R.G.: Potential for transmission of avian influenza viruses to pigs. Journal of General Virology, 75, 2183-2188, 1994.
  116. Yasuda, J., Nakada, S., Kato, A., Toyoda, T., and Ishihama, A.: Molecular assembly of influenza virus: Association of the NS2 protein with virion matrix. Virology;, 196, 249-255, 1993.
  117. Yasuda, J., Toyoda, T., Nakayama, M., and Ishihama, A.: Regulatory effects of matrix protein variations on influenza virus growth. Archives of Virology, 133, 283-294, 1993.
  118. Yasuda, J., Shortridge, K.F., Shimizu, Y., and Kida, H.: Molecular evidence for a role of domestic ducks in the introduction of avian H3 influenza viruses to pigs in southern China, where the A/Hong Kong/68 (H3N2) strain emerged. Journal of General Virology 72, 2007-2010, 1991.

総説・著書　その他

  1. 安田二朗：「BSL-4施設稼働により拓かれるわが国のウイルス研究の新局面」、ウイルス　72（1）、pp1-6、日本ウイルス学会、東京、2022年。
  2. 安田二朗：「BSL-4施設稼働により進展するウイルス感染症研究」、臨時増刊号 特集「ウイルス感染症の克服に向けた新展開」（渡辺登喜子、松浦善治編）月刊細胞、vol.54(5), pp23-26(253-256)、ニューサイエンス社、東京、2022年。
  3. 安田二朗：「新興感染症/バイオテロ」、遺伝学の百科事典（日本遺伝学会編）、pp40-41、丸善出版、東京、2022年。
  4. 安田二朗：「長崎大学BSL-4施設」、LABIO 21、No.84,pp22-25、日本実験動物協会、東京、2021年。
  5. 赤須 理紗子、沼澤昭、安田二朗：「「アレスシックイ」と接触感染対策シリーズの開発」、抗ウイルス・抗菌製品開発（松村吉信監修）、pp299-308、NTS、東京、2021年。
  6. 安田二朗：「バイオセーフティと病原微生物の取り扱い」、標準微生物学第14版（神谷茂監修）、pp624-629、医学書院、東京、2021年。
  7. 安田二朗：「BSL-4施設の役割と必要性」、感染症、294（Vol.50 No.4）、アステラス製薬株式会社、東京、2020年。
  8. 安田二朗：「ラッサ熱」、最新醫學（編）、74（4）、pp453-463、最新医学社、大阪、2019年。
  9. 安田二朗：「ラッサ熱と南米出血」グローバル時代のウイルス感染症（西條政幸編）、pp144-147、日本医事新報社、東京、2019年。
  10. 安田二朗：「ラッサ熱」、増刊号特集「グローバル化・温暖化と感染症対策」（岩田敏編）小児科臨床、vol.70, pp2348-2351(252-255)、日本小児医事出版社、東京、2017年。
  11. 安田二朗：「BSL-4施設の役割と必要性」、“新興・再興感染症と感染症対策”生体の科学、66（4）、pp360-363、医学書院、東京、2015年。
  12. 安田二朗：「エボラ出血熱の臨床的特徴と検査法」、Medical Technology、550　(43.8)、pp863-867、医歯薬出版株式会社、東京、2015年。
  13. 河岡義裕、安田二朗：「BSL-4施設は国防である―日本の感染症研究の実情―」、公研　622（53.6）、pp38-52、公益産業研究調査会、2015年。
  14. 安田二朗：「今、警戒すべき輸入ウイルス感染症」、呼吸34（6）、pp535-541、一般社団法人呼吸研究、2015年。
  15. 安田二朗：ウイルス性出血熱、化学療法の領域29（8）、pp33-40、医薬ジャーナル社、大阪、2013年。
  16. 安田二朗：ウイルス性出血熱、今日の治療と看護（永井良三、大田健編）、pp925-927、南江堂、東京、2013年。
  17. 安田二朗：「ウイルス性出血熱」、内科学 第11版、朝倉書店、2017年。
  18. 安田二朗：【エボラウイルス病とマールブルグ病】急がれる創薬とワクチン・診断法開発、“感染症最前線とグローバル・ヘルス”医学のあゆみ（永井美之編）253（1）4月4日号、pp26-30、医歯薬出版、東京、2015年。
  19. 安田二朗：エボラ出血熱（エボラウイルス病）、”新興再興ウイルス感染症”BIO Clinica、30(4)、pp42-45、北隆館、東京、2015年。
  20. Urata, S., Yasuda, J.: Molecular Mechanism of Arenavirus Assembly and Budding. Viruses, 4(10), 2049-2079, 2012
  21. Yasuda, J.: Ebolavirus Replication and Tetherin/BST-2. Front Microbiol., 3: 111, 2012
  22. Emonet, SE.*, Urata, S.*, de la Torre, JC.*, Arenavirus reverse genetics: New approaches for the investigation of arenavirus biology and development of antiviral strategies. (* Equal contribution), Virology, 411 (2), 416-25, 2011
  23. Urata, S., de la Torre, S.: Arenavirus budding. Advances in Virology, Article ID 180326, 2011
  24. Kurosaki, Y., and *Yasuda, J.: Ebola Viruses. In: Molecular detection of human viral pathogens (Liu, D., ed.), Taylor & Francis CRC Press, 559-572, 2010.
  25. *Yasuda, J.: Marburg virus budding: ESCRT of progeny virion to the outside of the cell. Future Virology, 5, 627-637, 2010.
  26. *Yasuda, J.: Laboratory diagnosis of SARS. In: SARS (Mizutani, T., ed.), Transworld Research Network, 77-87, 2006.
  27. Ishihama, A., Toyoda, T., Kobayashi, M., Yasuda, J., Asano, Y., and Nakayama, M.: Formation and control of influenza virus RNA polymerase. In: Options for the Control of Influenza II (Hannoun, C. et al., eds.), 289-297, 1993.
  28. 安田二朗：ウイルス出芽とESCRT～新生ウイルスを細胞外へエスコートする機構～、"メンブレントラフィックの奔流—分子から細胞、そして個体へ" 蛋白質・核酸・酵素、12月号増刊　53（16）（大野博司、吉森保編）、pp2251-2256、共立出版、東京、2008年。
  29. 安田二朗：全自動モバイル型生物剤センシングシステム、未来材料、11月号、pp58-62、エヌティーエス社、東京、2008年。
  30. 安田二朗：ユビキチンとウイルス出芽、"ユビキチン研究の新展開—メカニズムから疾患研究へ" 別冊•医学のあゆみ（田中啓二編）、pp114-118、医歯薬出版、東京、2006年。
  31. 安田二朗：HIV出芽とTsg101、ウイルス　55（２）、pp281-286、日本ウイルス学会、東京、2005年。
  32. 安田二朗、藤浪良仁：病原微生物の検査、"捜査のための法科学"（高取健彦編）、pp149-160、令文社、東京、200４年。
  33. 安田二朗：ユビキチンとウイルス出芽—ウイルス出芽とMVB sorting pathway、医学のあゆみ　211（1）、pp114-118、医歯薬出版、東京、2004年。
  34. 安田二朗、中尾光善：Nedd4ユビキチンリガーゼファミリーとウイルス出芽機構、現代医療　36（４）、pp69-74、現代医療社、東京、2004年。
  35. 安田二朗、岩倉洋一郎：トランスジェニックマウスの作製法、"実験医学別冊新遺伝子工学ハンドブック"改訂第4版（村松正實、山本雅編）、pp248-253、羊土社、東京、2003年。
  36. 安田二朗、Eric Hunter、中尾光善、志田壽利：ユビキチンリガーゼNedd4樣タンパク質によるレトロウイルスの出芽制御、細胞工学21（10）、pp1222-1223、秀潤社、東京、2002年。
  37. 安田二朗、岩倉洋一郎：トランスジェニックマウスの作製法、"実験医学別冊新遺伝子工学ハンドブック"改訂第３版（村松正實、山本雅編）、pp234-238、羊土社、東京、1999年。