Assistant Professors Shinya Miyazaki and Yukiko Miyazaki at the Institute have developed a new genetically modified reporter malaria parasite that facilitates malaria drug discovery. The manuscript is published in Communications Biology. We hope that the genetically modified reporter line will be used to develop new anti-malarial drugs that target multiple stages of the parasites.
Link to the manuscript.
A versatile Plasmodium falciparum reporter line expressing NanoLuc enables highly sensitive multi-stage drug assays | Communications Biology (nature.com) https://www.nature.com/articles/s42003-023-05078-5
Link to Nagasaki Univ website
A genetically engineered Plasmodium falciparum expressing NanoLuc as an innovative tool for malaria drug discovery (nagasaki-u.ac.jp) https://www.nagasaki-u.ac.jp/ja/guidance/kouhou/press/file/2023/20230721-1-2.pdf
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