Molecular & Cellular Biology Unit

At the Molecular & Cellular Biology Unit in Central Laboratory in NEKKEN, the state-of-the-art research equipment is provided including 8 Capillary DNA sequencers, High-throughput sequencers Real time PCR systems, Flow cytometers, Cell sorter system, Multiplex assay systems, Chemiluminescence imaging systems, and Multimode plate readers. Additionally, as the commonly used research equipment, MilliQ system, Ultracentrifuge machines, Vacuum Concentrators, Freeze dryers, Darkroom, and Laboratory cold room are also provided. Molecular & Cellular Biology Unit members (as of A pril 1, 2024, Fumika Mi-ichi, Akemi Ura, and Ayumi Fujimatsu) are in charge of maintaining these research facilities.

We are interested in biological phenomena presented by Entamoeba histolytica, the causative parasite for amoebiasis; for example, parasitic life cycle adaptation. We employ various approaches including molecular and cellular biology, lipid biochemistry, and omics. Currently, we focus on sulfolipid metabolism, very long chain acyl ceramide metabolism, and molecular mechanism under lying cyst formation in Entamoeba. As of April 1, 2024, members are Fumika Mi-ichi, principal investigator, Tam Kha Vo, Assistant Professor, and Kyoko Nagatomo, technical staff.

Members

Professor
Fumika Miichi
Research Fellow
Tam Yamaguchi
Assistant
Akemi Ura
Assistant
Kyoko Nagatomo
Assistant
Ayumi Fujimatsu

Recent main research achievement

  1. Mi-ichi et al. Parasitol Int 2024; 99: 102844.
  2. Mi-ichi et al. mSphere 2023; 8(5): e0017423.
  3. Mi-ichi et al. mSphere 2022; 7(4): e0029922.
  4. Mi-ichi et al. Microbiol Spectr 2021; 9(1): e0051121.
  5. Mi-ichi et al. mSphere 2021; 6(2): e00174-21.

Achievement list