Department of Protozoology
 Nagasaki Univ   Institute of Tropical Medicine Department of Protozoology Kaneko

Oct/2002, Kashiwa-jima Osamu Kaneko, MD, PhD
Professor
Osaka City Univ, Medical School, 1990. [Link]
Osaka City Univ, Graduate School, Medical Science, 1996.
Lab Parasitic Dis, NIAID, NIH, USA, Post-Doc, 1996-99. [Link]
Ehime Univ, School of Medicine, Dept Mol Parasitol, Instructor, 2000-2004. [Link]
Ehime Univ, School of Medicine, Dept Mol Parasitol, Associate Professor, 2004-2007.
Nagasaki Univ, Inst Trop Med, Dept Protozool. 2007-
Address Department of Protozoology
Institute of Tropical Medicine, Nagasaki University
Sakamoto 1-12-4, Nagasaki 852-8523, Japan
Phone / Fax (+81)-95-819-7838 / (+81)-95-819-7805
E-mail
Scientific Interest Invasion mechanism of erythrocyte by malaria merozoites
Molecular Epidemiology of the Plasmodium invasion-related molecules
Technique Molecular and Cell Biology
Hobby Climbing, Underwater Photography
  Theme :: Publication :: Award


 
Theme

Invasion mechanism of the erythrocytes by malaria merozoites

Basic data for Plasmodium falciparum
Origin of some P. falciparum strains
Reports for the cross-contamination of P. falciparum strains
Basic values for P. falciparum.

 

Publications

Research Article

[Invasion of the erythrocytes]

Otsuki H, Kaneko O, Thongkukiatkul A, Tachibana M, Iriko H, Takeo S, Tsuboi T, Torii M. Single amino acid substitution in Plasmodium yoelii erythrocyte ligand determines its localization and controls parasite virulence. Proc Natl Acad Sci U S A 106(17):7167-72 (2009/04) [Abstract]

Iriko H, Jin L, Kaneko O, Takeo S, Han T-T, Tachibana M, Otsuki H, Torii M, Tsuboi T, A small-scale systematic analysis of alternative splicing in Plasmodium falciparum. Parasitol Int 58:196-9 (2009/06) [Abstract]

Cao J, Kaneko O, Thongkukiatkul A, Tachibana M, Otsuki H, Gao Q, Tsuboi T, Torii M. Rhoptry neck protein RON2 forms a complex with microneme protein AMA1 in Plasmodium falciparum merozoites. Parasitol Int 58:29-35 (2009) [Abstract]

Mphande FA, Ribacke U, Kaneko O, Kironde F, Winter G, Wahlgren M.  SURFIN4.1, a schizont-merozoite associated protein in the SURFIN family of Plasmodium falciparum. Malaria J 7:116 (2008) [Abstract] [Open Access]

Iriko H, Kaneko O, Otsuki H, Tsuboi T, Su XZ, Tanabe K, Torii M.  Diversity and evolution of the rhoph1/clag multigene family of Plasmodium falciparum. Mol Biochem Parasitol158(1):11-21 (2008) [Abstract]

Cortés A, Carret C, Kaneko O, Yim-Lim BYS, Ivens A, Holder AA.  Epigenetic silencing of Plasmodium falciparum genes linked to erythrocyte invasion. PLoS Pathog 3:e107 (2007) [Abstract] [Open Access]

Moll K, Chene A, Ribacke U, Kaneko O, Nilsson S, Winter G, Haeggstrom M, Pan W, Berzins K, Wahlgren M, Chen Q. A novel DBL-domain of the P. falciparum 332 molecule involved in erythrocyte adhesion. PLoS ONE 2:e477 (2007) [Abstract] [Open Access]

Ghoneim A, Kaneko O, Tsuboi T, Torii M.  The Plasmodium falciparum RhopH2 promoter and first 24 amino acids are sufficient to target proteins to the rhoptries. Parasitol Int. 56(1):31-43 (2007/03) [Abstract]

Kaneko O, Yim-Lim BYS, Iriko H, Ling IT, Otsuki H, Grainger M, Tsuboi T, Adams JH, Mattei D, Holder AA, Torii M. Apical expression of three RhopH1/Clag proteins as components of the Plasmodium falciparum RhopH complex. Mol Biochem Parasitol 143(1):20-28 (2005/09).
[Abstract]

Winter G, Kawai S, Haeggstrom M, Kaneko O, von Euler A, Kawazu S, Palm D, Fernandez V, Wahlgren M. SURFIN is a polymorphic antigen expressed on Plasmodium falciparum merozoites and infected erythrocytes. J Exp Med 201(11):1853-63 (2005/06).
[Abstract]

Rungruang T, Kaneko O, Murakami Y, Tsuboi T, Hamamoto H, Akimitsu N, Sekimizu K, Kinoshita T, Torii M. Erythrocyte surface glycosylphosphatidyl inositol anchored receptor for the malaria parasite. Mol Biochem Parasitol 140(1):13-21 (2005).
[Abstract]

Preiser P, Renia L, Singh N, Balu B, Jarra W, Voza T, Kaneko O, Blair P, Torii M, Landau I, Adams JH. Antibodies against MAEBL ligand domains M1 and M2 inhibit sporozoite development in vitro.  Infect Immun 72(6):3604–8 (2004) [Abstract] [Full Text]

 Ling IT, Florens L, Dluzewski AR, Kaneko O, Grainger M, Yim- Lim BYS, Tsuboi T, Hopkins JM 3rd, Johnson JR, Torii M, Bannister LH, Yates JR, Holder AA and Mattei D. The Plasmodium falciparum clag9 gene encodes a rhoptry protein that is transferred to the host erythrocyte upon invasion. Mol Microbiol 52(1):107-18 (2004) [Abstract]

Mayer DC, Mu JB, Kaneko O, Duan J, Su XZ, Miller LH. Polymorphism in the Plasmodium falciparum erythrocyte-binding ligand JESEBL/EBA-181 alters its receptor specificity. Proc Natl Acad Sci USA. 101: 2518-23 (2004)  [Abstract] [Full Text]

Ling IT, Kaneko O, Narum D, Tsuboi T, Howell S , Taylor HM, Scott-Finnigan TJ, Torii M, Holder AA. Characterisation of the rhoph2 gene of Plasmodium falciparum and Plasmodium yoelii. Mol Biochem Parasitol 127(1):47-57 (2003).  [Abstract]

Michon P, Stevens JR, Kaneko O, Adams JH. Evolutionary relationships of conserved cysteine-rich motifs in adhesive molecules of malaria parasites. Mol Biol Evol 19(7):1128-42 (2002). [Abstract] [Full Text]

Kaneko O, Mu J, Tsuboi T, Su X, Torii M. Gene structure and expression of a Plasmodium falciparum 220-kilodalton protein homologous to the Plasmodium vivax reticulocyte binding proteins. Mol Biochem Parasitol 121:275-8 (2002). [No Abstract]

Review Article

Culleton R, Kaneko O. Erythrocyte binding ligands in malaria parasites: Intracellular trafficking and parasite virulence. Acta Tropica 114(3):131-7 (2010/06) [Abstract]

Udomsangpetch R, Kaneko O, Chotivanich K, Sattabongkot J. Cultivation of Plasmodium vivax. Trends Parasitol 24(2):85-8. (2008) [Abstract]

Kaneko O.  Erythrocyte invasion: vocabulary and grammar of the Plasmodium rhoptry. Parasitol Int 56(4):255-62 (2007). [Abstract]

Adams JH, Kaneko O, Blair PL, Peterson DS. An Expanding ebl Family of Plasmodium falciparum.. Trends Parasitol 17(6): 297-9(2001) [No Abstract]

Tanabe K, Sakihama N, Kaneko O, Saito-Ito A, Kimura M. A PCR method for molecular epidemiology of Plasmodium falciparum Msp-1. Tokai J Exp Clin Med 23(6): 375-81 (1998) [Abstract]

Ferreira MU, Kaneko O, Kimura M, Liu Q, Kawamoto F, Tanabe K. Allelic diversity at the merozoite surface protein-1 locus in natural Plasmodium falciparum populations: a brief overview.  Mem Inst Oswaldo Cruz, Rio de Janeiro, 93(5): 631-638 (1998) [Abstract] [Full Text]

More

Award and others

MR4 Scientific Advisory Committee member  2006.Sep-

The Japanese Society of Parasitology, Young Investigator Award, 2002.  (for "The high molecular mass rhoptry protein, RhopH1, is encoded by members of the clag multigene family in Plasmodium falciparum and Plasmodium yoelii")

Osaka City Academy of Medicine, Mayer's Award, 1998
(for "Plasmodium falciparum: Allelic variation in the merozoite surface protein 1 gene in wild isolates from Southern Vietnam")

Invited Speaker of SINGAPORE Malaria Network Meeting 2008, 2008.
Invited Speaker of the 9th International Congress of Parasitology, 1998.

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