Yoshino R, Yasuo N, Hagiwara Y, Ishida T, Inaoka DK, Amano Y, Tateishi Y, Ohno K, Namatame I, Niimi T, Orita M, Kita K, Akiyama Y, Sekijima M: Discovery of a Hidden Trypanosoma cruzi Spermidine Synthase Binding Site and Inhibitors through In Silico, In Vitro, and X-ray Crystallography. ACS Omega 8(29): 25850-25860, 2023.
Miyazaki Y, Vos MW, Geurten FJA, Bigeard P, Kroeze H, Yoshioka S, Arisawa M, Inaoka DK, Soulard V, Dechering KJ, Franke-Fayard B, Miyazaki S: A versatile Plasmodium falciparum reporter line expressing NanoLuc enables highly sensitive multistage drug assays. Commun Biol 6(1): 713, 2023.
Hidayati AR, Melinda, Ilmi H, Sakura T, Sakaguchi M, Ohmori J, Hartuti ED, Tumewu L, Inaoka DK, Tanjung M, Yoshida E, Tokumasu F, Kita K, Mori M, Dobashi K, Nozaki T, Syafruddin D, Hafid AF, Waluyo D, Widyawaruyanti A: Effect of geranylated dihydrochalcone from Artocarpus altilis leaves extract on Plasmodium falciparum ultrastructural changes and mitochondrial malate: Quinone oxidoreductase. Int J Parasitol Drugs Dsist 21: 40-50, 2023.
Enkai S, Kouguchi H, Inaoka DK, Shiba T, Hidaka M, Matsuyama H, Sakura T, Yagi K, Kita K: Killing Two Birds with One Stone: Discovery of Dual Inhibitors of Oxygen and Fumarate Respiration in Zoonotic Parasite, Echinococcus multilocularis. Antimicrob Agents Chemother 67(3): e0142822, 2023.
Kabongo AT, Acharjee R, Sakura T, Bundutidi GM, Hartuti ED, Davies C, Gundogdu O, Kita K, Shiba T, Inaoka DK: Biochemical characterization and identification of ferulenol and embelin as potent inhibitors of malate:quinone oxidoreductase from Campylobacter jejuni. Front Mol Biosci 10: 1095026, 2023.
2022年
Komatsuya K, Sakura T, Shiomi K, Ōmura S, Hikosaka K, Nozaki T, Kita K, Inaoka DK: Siccanin Is a Dual-Target Inhibitor of Plasmodium falciparum Mitochondrial Complex II and Complex III. Pharmaceuticals (Basel) 5(7):903, 2022.
Alshaweesh J, Nakamura R, Tanaka Y, Hayashishita M, Musa A, Kikuchi M, Inaoka DK, Hamano S: Leishmania major Strain-Dependent Macrophage Activation Contributes to Pathogenicity in the Absence of Lymphocytes. Microbiol Spectr 10(5): e0112622, 2022.
Tun MMN, Sakura T, Sakurai Y, Kurosaki Y, Inaoka DK, Shioda N, Yasuda J, Kita K, Morita K: Antiviral activity of 5-aminolevulinic acid against variants of severe acute respiratory syndrome coronavirus 2. Trop Med Health 50(1): 6, 2022.
Tun MMN, Sakura T, Sakurai Y, Kurosaki Y, Inaoka DK, Shioda N, Yasuda J, Kita K, Morita K: 5-Aminolevulinic acid antiviral efficacy against SARS-CoV-2 omicron variant in vitro. Trop Med Health 50(1):30, 2022.
Kouguchi H, Enkai S, Matsuyama H, Hidaka M, Inaoka DK, Kita K, Yagi K: Data on the combined effect of atovaquone, mefloquine, and 3-bromopyruvic acid against Echinococcus multilocularis protoscoleces. Data Brief 45: 108707, 2022.
2021年
Nara T, Nakagawa Y, Tsuganezawa K, Yuki H, Sekimata K, Koyama H, Ogawa N, Honma T, Shirouzu M, Fukami T, Matsuo Y, Inaoka DK, Kita K, Tanaka A: The ubiquinone synthesis pathway is a promising drug target for Chagas disease. PLoS One 16(2): e0243855, 2021.
Sakurai Y, Ngwe Tun MM, Kurosaki Y, Sakura T, Inaoka DK, Fujine K, Kita K, Morita K, Yasuda J: 5-amino levulinic acid inhibits SARS-CoV-2 infection in vitro. Biochem Biophys Res Commun 545: 203-207, 2021.
Nurkanto A, Jeelani G, Santos HJ, Rahmawati Y, Mori M, Nakamura Y, Goto K, Saikawa Y, Annoura T, Tozawa Y, Sakura T, Inaoka DK, Shiomi K, Nozaki T: Characterization of Plasmodium falciparum Pantothenate Kinase and Identification of Its Inhibitors From Natural Products. Front Cell Infect Microbiol 11: 639065, 2021.
Enkai S, Kouguchi H, Inaoka DK, Irie T, Yagi K, Kita K: In vivo efficacy of combination therapy with albendazole and atovaquone against primary hydatid cysts in mice. Eur J Clin Microbiol Infect Dis 40: 1815-1820, 2021.
Pramisandi A, Kurnia K, Chrisnayanti E, Bernawati P, Dobashi K, Mori M, Mahsunah AH, Nonaka K, Matsumoto A, Kristiningrum, Hidayati DN, Dewi D, Prabandari EE, Amalia E, Rahmawati Y, Nurkanto A, Inaoka DK, Waluyo D, Kita K, Nozaki T, Ōmura S, Shiomi K: Gentisyl alcohol and homogentisic acid: Plasmodium falciparum dihydroorotate dehydrogenase inhibitors isolated from fungi. J Gen Appl Microbiol 67: 114-117, 2021.
Villafraz O, Baudouin H, Mazet M, Kulyk H, Dupuy JW, Pineda E, Botté C, Inaoka DK, Portais JC, Bringaud F:The Trypanosome UDP-Glucose Pyrophosphorylase Is Imported by Piggybacking into Glycosomes, Where Unconventional Sugar Nucleotide Synthesis Takes Place. mBio 12(3): e0037521, 2021.
Hartuti ED, Sakura T, Tagod MSO, Yoshida E, Wang X, Mochizuki K, Acharjee R, Matsuo Y, Tokumasu F, Mori M, Waluyo D, Shiomi K, Nozaki T, Hamano S, Shiba T, Kita K, Inaoka DK: Identification of 3,4-Dihydro-2H,6H-pyrimido[1,2-c][1,3] benzothiazin-6-imine Derivatives as Novel Selective Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase. Int J Mol Sci 2(13): 7236, 2021.
Talaam KK, Inaoka DK, Hatta T, Tsubokawa D, Tsuji N, Wada M, Saimoto H, Kita K, Hamano S: Mitochondria as a Potential Target for the Development of Prophylactic and Therapeutic Drugs against Schistosoma mansoni Infection. Antimicrob Agents Chemother 2021 65(10): e0041821, 2021.
Acharjee R, Talaam KK, Hartuti ED, Matsuo Y, Sakura T, Gloria BM, Hidano S, Kido Y, Mori M, Shiomi K, Sekijima M, Nozaki T, Umeda K, Nishikawa Y, Hamano S, Kita K, Inaoka DK: Biochemical Studies of Mitochondrial Malate: Quinone Oxidoreductase from Toxoplasma gondii. Int J Mol Sci 22(15): 7830, 2021.
Waluyo D, Prabandari EE, Pramisandi A, Hidayati DN, Chrisnayanti E, Puspitasari DJ, Dewi D, Suryani, Kristiningrum, Oktaviani AN, Afrianti KR, Nonaka K, Matsumoto A, Tokiwa T, Adipratiwi N, Ariyani T, Hartuti ED, Putri TZ, Rahmawati Y, Inaoka DK, Miyazaki Y, Sakura T, Nurlaila, Siska E, Kurnia K, Bernawati P, Melinda, Mahsunah AH, Nugroho NB, Mori M, Dobashi K, Yamashita M, Nurkanto A, Watanabe A, Shiomi K, Wibowo AE, Nozaki T: Exploring natural microbial resources for the discovery of anti-malarial compounds. Parasitol Int 85:102432, 2021.
Fukumoto J, Sakura T, Matsubara R, Tahara M, Matsuzaki M, Nagamune K: Rhoptry kinase protein 39 (ROP39) is a novel factor that recruits host mitochondria to the parasitophorous vacuole of Toxoplasma gondii. Biol Open 10(9): bio058988, 2021.
2020年
Young L, Rosell-Hidalgo A, Inaoka DK, Xu F, Albury M, May B, Kita K, Moore AL: Kinetic and structural characterisation of the ubiquinol-binding site and oxygen reduction by the trypanosomal alternative oxidase. Biochim Biophys Acta Bioenerg 1861(10): 148247, 2020.
Pramisandi A, Dobashi K, Mori M, Nonaka K, Matsumoto A, Tokiwa T, Higo M, Kristiningrum, Amalia E, Nurkanto A, Inaoka DK, Waluyo D, Kita K, Nozaki T, Ōmura, Shiomi K: Microbial inhibitors active against Plasmodium falciparum dihydroorotate dehydrogenase derived from an Indonesian soil fungus, Talaromyces pinophilus BioMCC-f.T.3979. J Gen Appl Microbiol 66(5): 273-278, 2020.
Mochizuki K, Inaoka DK, Mazet M, Shiba T, Fukuda K, Kurasawa H, Millerioux Y, Boshart M, Balogun EO, Harada S, Hirayama K, Bringaud F, Kita K: The ASCT/SCS cycle fuels mitochondrial ATP and acetate production in Trypanosoma brucei. Biochim Biophys Acta Bioenerg 1861(11): 148283, 2020.
Adamu A, Jada MS, Haruna HMS, Yakubu BO, Ibrahim MA, Balogun EO, Sakura T, Inaoka DK, Kita K, Hirayama K, Culleton R, Shuaibu MN: Plasmodium falciparum multidrug resistance gene-1 polymorphisms in Northern Nigeria: implications for the continued use of artemether-lumefantrine in the region. Malar J 19: 439, 2020.
Sato D, Hartuti ED, Inaoka DK, Sakura T, Amalia E, Nagahama M, Yoshioka Y, Tsuji N, Nozaki T, Kita K, Harada S, Matsubayashi M, Shiba T: Structural and Biochemical Features of Eimeria tenella Dihydroorotate Dehydrogenase, a Potential Drug Target. Genes (Basel) 11(12): 1468, 2020.
Enkai S, Kouguchi H, Inaoka DK, Irie T, Yagi K, Kita K: Effect of the anti-parasitic compounds pyrvinium pamoate and artemisinin in enzymatic and culture assays: Data on the search for new anti-echinococcal drugs. Data Brief 37(34): 106629, 2020.
2019年
Balogun EO, Inaoka DK, Shiba T, Tsuge C, May B, Sato T, Kido Y, Nara T, Aoki T, Honma T, Tanaka A, Inoue M, Matsuoka S, Michels PAM, Watanabe YI, Moore AL, Harada S, Kita K：Discovery of Trypanocidal Coumarins With Dual Inhibition of Both the Glycerol Kinase and Alternative Oxidase of Trypanosoma Brucei brucei. FASEB J 33(11): 13002-13013, 2019.
Wang X, Miyazaki Y, Inaoka DK, Hartuti ED, Watanabe YI, Shiba T, Harada S, Saimoto H, Burrows JN, Benito FJG, Nozaki T, Kita K：Identification of Plasmodium falciparum Mitochondrial Malate: Quinone Oxidoreductase Inhibitors from the Pathogen Box. Genes (Basel) 10(6): 471, 2019.
Araki Y, Awakawa T, Matsuzaki M, Cho R, Matsuda Y, Hoshino S, Shinohara Y, Yamamoto M, Kido Y, Inaoka DK, Nagamune K, Ito K, Abe I, Kita K：Complete biosynthetic pathways of ascofuranone and ascochlorin in Acremonium egyptiacum. Proc Natl Acad Sci USA 116(17): 8269-8274, 2019.
Shiba T, Inaoka DK, Takahashi G, Tsuge C, Kido Y, Young L, Ueda S, Balogun EO, Nara T, Honma T, Tanaka A, Inoue M, Saimoto H, Harada S, Moore AL, Kita K：Insights into the ubiquinol/dioxygen binding and proton relay pathways of the alternative oxidase. Biochim Biophys Acta Bioenerg 1860(5): 375-382, 2019.
Matsubayashi M, Inaoka DK, Komatsuya K, Hatta T, Kawahara F, Sakamoto K, Hikosaka K, Yamagishi J, Sasai K, Shiba T, Harada S, Tsuji N, Kita K：Novel Characteristics of Mitochondrial Electron Transport Chain from Eimeria tenella. Genes (Basel) 10(1): 29, 2019.
