Boussoffara, T., Labidi, I., Trimèche, M., Chelbi, I., Dachraoui, K., Msallem, N., Abdo Saghir Abbas, M., Cherni, S., Singh, K.P., Kaviraj, S., Dey, R., Varikuti, S., Gannavaram, S., da S Pereira, L., Zhang, W.W., Lypaczewski, P., Hamano, S., Kato, H., Singh, S., Louzir, H., Nakhasi, H.L., Satoskar, A.R., Matlashewski, G., Zhioua, E. LmCen-/- based vaccine is protective against canine visceral leishmaniasis following three natural exposures in Tunisia. NPJ Vaccines. 2025; 10(1): 31.
Bundutidi, G.M., Mochizuki, K., Matsuo, Y., Hayashishita, M., Sakura, T., Ando, Y., Cook, G.M., Rajib, A., Bringaud, F., Boshart, M., Hamano, S., Sekijima, M., Hirayama, K., Kita, K., Inaoka, D.K.: Development of tolerance to bedaquiline by overexpression of trypanosomal acetate: succinate CoA transferase in Mycobacterium smegmatis. Commun Biol. 2025; 8(1): 187.
Kokubo-Tanaka, M., Kildemoes, A.O., Chadeka, E.A., Cheruiyot, B.N., Moriyasu, T., Sassa, M., Nakamura, R., Kikuchi, M., Fujii, Y., de Dood, C.J., Corstjens, P. L. A. M., Kaneko, S., Maruyama, H., Njenga, S.M., de Vrueh, R., Hokke, C.H., *Hamano, S.: Detection and analysis of Serpin and RP26 specific antibodies for monitoring Schistosoma haematobium transmission. PLoS Negl Trop Dis. 2025, 19(1): e0012813.
Ouji, Y., Hamasaki, M., Misu, M., Yoshikawa, M., Hamano, S.: Labeling of miracidium using fluorescent agents to visualize infection of schistosome in intermediate host snails. Parasitol. Int. 2025; 104: 102994.
Ouji, Y., Hamasaki, M., Misu, M., Yoshikawa, M., Hamano, S.: Simple preservation of schistosome eggs with high infectivity up to 12 weeks. Parasitol. Int. 2024; 106: 103020.
Sepahpour, T., Alshaweesh, J., Azodi, N., Singh, K., Ireland, D.D.C., Valanezhad, F., Nakamura, R., Satoskar, A.R., *Dey, R., *Hamano, S., *Nakhasi, H.L., *Gannavaram, S.: Downregulation of IRF7-mediated type-I interferon response by LmCen-/- parasites is necessary for protective immunity. NPJ Vaccines. 2024; doi.org/10.1038/s41541-024-01032-6.
Osawa, R., Jo, T.S., Nakamura, R., Futami, K., Itayama, T., Chadeka, E.A., Ngetich, B., Nagi, S., Kikuchi, M., Njenga, S.M., Ouma, C., Sonye, G.O., Hamano, S., Minamoto, T.: Methodological assessment for efficient collection of Schistosoma mansoni environmental DNA and improved schistosomiasis surveillance in tropical wetlands. Acta Trop. 2024 11: 107402.
Randrianasolo, B.S., Jøker, K., Arenholt, L.T.S., Rabozakandraina, T.O.O., Ramarokoto, C.E., Brønnum, D., Jensen, M., Christensen, S.L., Jensen, J.S., Corstjens, P., van Dam, G.J., Kobayashi, N., Hamano, S. and Leutscher, P.D.C.: An assessment of gynecological manifestations in women with female genital schistosomiasis with reference to Schistosoma biomarkers, sexually transmitted infections and bacterial vaginosis. Front Trop Dis. 2024; 5: 1322667.
Arenholt, L.T.S., Randrianasolo, B.S., Rabozakandraina, T.O.O., Ramarokoto, C.E., Jøker, K., Kæstel Aarøe K., Brønnum, D., Bundgaard Nielsen C., Sørensen, S., Lumholdt, M., Jensen, M., Lundbye-Christensen, S., Jensen, J.S., Corstjens, P., Hoekstra, P., J van Dam, G., Kobayashi, N., Hamano, S. and Leutscher, P.D.C.: Repeated versus single praziquantel dosing regimen in treatment of female genital schistosomiasis: a phase 2 randomised controlled trial showing no difference in efficacy. Front Trop Dis. 2024; 5:1322652.
Cheruiyot, N.B., *Nagi, S., Chadeka, A.E., Takeuchi, R., Sassa, M., Felix, B., Kobayashi, N., Moriyasu, T., Masaku, J., Okomo, G., Ouma, C., Njomo, D., Njenga, S.M., *Hamano, S.: Barriers and misconceptions hindering reduction of intestinal schistosomiasis in Mbita Sub-County, Western Kenya. Trop Med Health. 2024; 52(1): 38.
Kishino M, Hida A, Chadeka EA, Inoue M, Osada-Oka M, Matsumoto S, Njenga SM, Hamano S, Nagi S : Association between diet quality and risk of stunting among school-aged children in Schistosoma mansoni endemic area of western Kenya: a cross-sectional study. Trop Med Health. 2024; 52(1): 12.
Mi-Ichi F, Hamano S, Yoshida H.: Links between cholesteryl sulfate-dependent and -independent processes in the morphological and physiological changes of Entamoeba encystation. Parasitol Int. 2024; 99: 102844.
Oljuskin T, Azodi N, Volpedo G, Bhattacharya P, Markle HL, Hamano S, Matlashewski G, Satoskar AR, Gannavaram S, Nakhasi HL : Leishmania major centrin knock-out parasites reprogram tryptophan metabolism to induce a pro-inflammatory response. iScience. 2023; 26(9): 107593.
Tayama Y, Mizukami S, Toume K, Komatsu K, Yanagi T, Nara T, Tieu P, Huy NT, Hamano S, Hirayama K.: Anti-Trypanosoma cruzi activity of Coptis rhizome extract and its constituents. Trop Med Health. 2023; 51(1): 12.
Takeuchi T, Nakamura R, Hamasaki M, Oyama M, Hamano S, Hatanaka T : In vitro evaluation of the effect of galectins on Schistosoma mansoni motility. BMC Res Notes. 2023; 16(1): 266.
濱野真二郎: 糸状虫（フィラリア）症、今日の治療指針 2023、医学書院、XXX. (査読無)
2022年
Alshaweesh J, Nakamura R, Tanaka Y, Hayashishita M, Musa A, Kikuchi M, Inaoka DK, Hamano S. : Leishmania major Strain-Dependent Macrophage Activation Contributes to Pathogenicity in the Absence of Lymphocytes. Microbiol Spectr. 2022; 10(5): e0112622.
Ouji Y, Hamasaki M, Misu M, Kitamura T, Hamano S, Yoshikawa M.: Schistosoma mansoni larvae in vitro cultures using Biomphalaria glabrata extracts. Acta Trop. 2022; 235: 106636.
Nwe KM, Ngwe Tun MM, Myat TW, Sheng Ng CF, Htun MM, Lin H, Hom NS, Soe AM, Elong Ngono A, Hamano S, Morita K, Thant KZ, Shresta S, Thu HM, Moi ML. : Acute-phase Serum Cytokine Levels and Correlation with Clinical Outcomes in Children and Adults with Primary and Secondary Dengue Virus Infection in Myanmar between 2017 and 2019. Pathogens. 2022; 11(5): 558.
2021年
Mukendi JPK, Nakamura R, Uematsu S, Hamano S: Interleukin (IL)-33 is dispensable for Schistosoma mansoni worm maturation and the maintenance of egg-induced pathology in intestines of infected mice. Parasit Vectors, 2021; 14(1): 70.
Mannan SB, Elhadad H, Loc TTH, Sadik M, Mohamed MYF, Nam NH, Thuong ND, Hoang-Trong BL, Duc NTM, Hoang AN, Elhusseiny KM, Minh LHN, Quynh TTH, Nghia TLB, Mai Nhu Y, Tieu TM, Hirayama K, Huy NT, Hamano S: Prevalence and associated factors of asymptomatic leishmaniasis: A systematic review and meta-analysis. Parasitol Int, 2021; 81: 102229.
Tanaka M, Kildemoes AO, Chadeka EA, Cheruiyot BN, Sassa M, Moriyasu T, Nakamura R, Kikuchi M, Fujii Y, de Dood CJ, Corstjens PLAM, Kaneko S, Maruyama H, Njenga SM, de Vrueh R, Hokke CH, Hamano S: Potential of antibody test using Schistosoma mansoni recombinant serpin and RP26 to detect light-intensity infections in endemic areas. Parasitol Int, 2021; 83: 102346.
Karmakar S, Ismail N, Oliveira F, Oristian J, Zhang WW, Kaviraj S, Singh KP, Mondal A, Das S, Pandey K, Bhattacharya P, Volpedo G, Gannavaram S, Satoskar M, Satoskar S, Sastry RV, Oljuskin T, Meneses C, Hamano S, Das P, Matlashewski G, Singh S, Kamhawi S, Dey R, Valenzuela JG, Satoskar A, Nakhasi HL: Preclinical validation of a live attenuated dermotropic Leishmania vaccine against vector transmitted fatal visceral leishmaniasis. Commun Biol, 2021; 4(1): 929.
Talaam KK, Inaoka DK, Hatta T, Tsubokawa D, Tsuji N, Wada M, Saimoto H, Kita K, Hamano S: Mitochondria as a potential target for the development of prophylactic and therapeutic drugs against Schistosoma mansoni infection. Antimicrob Agents Chemother, 2021; 65(10): e0041821.
Mi-ichi F, Sakaguchi M, Hamano S, Yoshida H: Entamoeba chitinase is required for mature round cyst formation. Microbiol Spectr, 2021; 9(1): e0051121.
Acharjee R, Talaam KK, Hartuti ED, Matsuo Y, Sakura T, Gloria BM, Hidano S, Kido Y, Mori M, Shiomi K, Sekijima M, Nozaki T, Umeda K, Nishikawa Y, Hamano S, Kita K, Inaoka DK: Biochemical studies of mitochondrial malate: quinone oxidoreductase from Toxoplasma gondii. Int J Mol Sci, 2021; 22(15): 7830.
Hartuti ED, Sakura T, Tagod MSO, Yoshida E, Wang X, Mochizuki K, Acharjee R, Matsuo Y, Tokumasu F, Mori M, Waluyo D, Shiomi K, Nozaki T, Hamano S, Shiba T, Kita K, Inaoka DK: Identification of 3,4-dihydro-2H,6H-pyrimido[1,2-c][1,3]benzothiazin-6-imine-derivatives as novel selective inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase. Int J Mol Sci, 2021; 22(13): 7236.
Nakamura R, Yoshizawa A, Moriyasu T, Deloer S, Senba M, Kikuchi M, Koyasu S, Moro K, Hamano S: Group 2 innate lymphoid cells exacerbate amebic liver abscess in mice. iScience, 2020; 23(9): 101544.
Latio LSY, Nam NH, Shah J, Smith C, Sakai K, Stonewall Shaban K, Idro R, Nishi M, Huy NT, Hamano S, Moji K: Economic burden of the persistent morbidity of nodding syndrome on caregivers in affected households in Northern Uganda. PLoS One, 2020; 15(9): e0238643.
Mohammed ES, Nakamura R, Kalenda YD, Deloer S, Moriyasu T, Tanaka M, Fujii Y, Kaneko S, Hirayama K, Ibrahim AI, El-Seify MA, Metwally AM, Hamano S: Dynamics of serological responses to defined recombinant proteins during Schistosoma mansoni infection in mice before and after the treatment with praziquantel. PLoS Negl Trop Dis, 2020; 14(9): e0008518.
Sassa M, Chadeka E.A, Cheruiyot N.B, Tanaka M, Moriyasu T, Kaneko S, Njenga S.M, Cox S.E, Hamano S: Prevalence and risk factors of Schistosoma mansoni infection among children under two years of age in Mbita, Western Kenya. PLoS Negl Trop Dis, 2020; 14(8): e0008473.
Mousa EAA, Sakaguchi M, Nakamura R, Abdella OH, Yoshida H, Hamano S, Mi-ichi F: The dynamics of ultrastructural changes during Entamoeba invadens encystation. Parasitology, 2020; 147(12): 1305-1312.
Zhang WW, Karmakar S, Gannavaram S, Dey R, Lypaczewski P, Ismail N, Siddiqui A, Simonyan V, Oliveira F, Coutinho-Abreu I, DeSouza-Vieira T, Meneses C, Oristian J, Serfim T, Musa A, Nakamura R, Saljoughi N, Volpedo G, Satoskar M, Satoskar S, Dagur P, McCoy J, Kamhawi S, Valenzuela J, Hamano S, Satoskar A. Matlashewski G, Nakhasi H: A second generation leishmanization vaccine with a markerless attenuated Leishmania major strain using CRISPR gene editing. Nature Commun, 2020; 11(1): 3461.
Hasegawa M, Pilotte N, Kikuchi M, Means AR, Papaiakovou M, Gonzalez AM, Maasch JRMA, Ikuno H, Sunahara T, Ásbjörnsdóttir KH, Walson JL, Williams SA, Hamano S; DeWorm3 Project Team. What does soil-transmitted helminth elimination look like? Results from a targeted molecular detection survey in Japan. Parasit Vectors, 2020; 13(1): 6.
Musa MA, Nakamura R, Hena A, Varikuti S Nakhasi HL, Goto Y, Satoskar AR, Hamano S: Lymphocytes influence Leishmania major pathogenesis in a strain-dependent manner. PLoS Negl Trop Dis, 2019; 13(11): e0007865.
Mi-ichi F, Ishikawa T, Tam VK, Deloer S, Hamano S, Hamada T, Yoshida H: Characterization of Entamoeba histolytica adenosine 5'-phosphosulfate (APS) kinase; validation as a target and provision of leads for the development of new drugs against amoebiasis. PLoS Negl Trop Dis, 2019; 13(8): e0007633.
Takeuchi T, Tamura M, Ishiwata K, Hamasaki M, Hamano S, Arata Y, Hatanaka T: Galectin-2 suppresses nematode development by binding to the invertebrate-specific galactoseβ1-4fucose glyco-epitope. Glycobiology, 2019; 29(6): 504-512.
Chadeka EA, Nagi S, Cheruiyot NB, Bahati F, Sunahara T, Njenga SM, Hamano S: A high-intensity cluster of Schistosoma mansoni infection around Mbita causeway, western Kenya: a confirmatory cross-sectional survey. Trop Med Health, 2019; 47: 26.
Moriyasu T, Nakamura R, Deloer S, Senba M, Kubo M, Inoue M, Culleton R, Hamano S: Schistosoma mansoni infection suppresses the growth of Plasmodium yoelii parasites in the liver and reduces gametocyte infectivity to mosquitoes. PLoS Negl Trop Dis, 2018; 12(1): e0006197.
Kijogi C, Kimura D, Bao LQ, Nakamura R, Chadeka EA, Cheruiyot NB, Bahati F, Yahata K, Kaneko O, Njenga SM, Ichinose Y, Hamano S, Yui K: Modulation of the immune responses by Plasmodium falciparum infection in asymptomatic children living in the endemic region of Mbita, western Kenya. Parasitol Int, 2018; 67(3): 284-293.
Inoue M, Niki M, Ozeki Y, Nagi S, Chadeka EA, Yamaguchi T, Osada-Oka M, Ono K, Oda T, Mwende F, Kaneko Y, Matsumoto M, Kaneko S, Ichinose Y, Njenga SM, Hamano S, Matsumoto S: High-density lipoprotein suppresses tumor necrosis factor alpha production by mycobacteria-infected human macrophages. Sci Rep, 2018; 8(1): 6736.
Mitsui Y, Ureña-Tatis KE, Aoki Y: Chemoattractant activity of tris(hydroxymethyl)aminomethane for Brugia pahangi infective third-stage larvae. J Helminthol, 2018; 92(3): 317-321.
Mitsui Y, Kato K: Application of non-fluorescent dyes to assess the antischistosomal effect of antimalarial drugs on Schistosoma mansoni adult worms. Jpn J Infect Dis, 2018; 71(5): 382-387.
Noguchi N, Nakamura R, Hatano S, Yamada H, Sun X, Ohara N, Yoshikai Y. Equal contribution: Interleukin-21 induces short-lived effector CD8+ T cells but does not inhibit their exhaustion after Mycobacterium bovis BCG infection in mice. Infect Immun, 2018; 86(8): e00147-18.
Ghosh P, Hasnain MG, Hossain F, Khan MAA, Chowdhury R, Faisal K, Mural MA, Baker J, Nath R, Ghosh D, Maruf S, Shomik MS, Haque R, Matlashewski G, Hamano S, Duthie MS, Mondal D: Evaluation of Real-time PCR for Diagnosis of Post-Kala-azar Dermal Leishmaniasis in Endemic Foci of Bangladesh. Open Forum Infect Dis, 2018; 5(10): ofy234.
Aksorn N, Roytrakul S, Kittisenachai S, Leelawat K, Chanvorachote P, Topanurak S, Hamano S, Lek-Uthai U: Novel Potential Biomarkers for Opisthorchis viverrini Infection and Associated Cholangiocarcinoma. In Vivo, 2018; 32(4): 871-878.
長谷川光子, Nils Pilotte, 菊池三穂子, Arianna Rubin Means, 是永正敬, Judd L. Walson, Steven A. Williams, 濱野真二郎 : Real-time PCRを用いた日本の土壌伝播蠕虫感染状況調査, Clin Parasitol, 2018; 29(1): 95-98.
Hamano, S. and William A. Petri Jr.: Chapter 209: Amoebiasis in “Feigin, Cherry, Demmler, Kaplan: Textbook of Pediatric Infectious Disease, 8th edition” , 2017; 8: 2118-2123.
Chadeka EA, Nagi S, Sunahara T, Cheruiyot NB, Bahati F, Ozeki Y, Inoue M, Osada-Oka M, Okabe M, Hirayama Y, Changoma M, Adachi K, Mwende F, Kikuchi M, Nakamura R, Dan Justin YK, Kaneko S, Hirayama K, Shimada M, Ichinose Y, Njenga SM, Matsumoto S, Hamano S: Spatial distribution and risk factors of Schistosoma haematobium and hookworm infections among schoolchildren in Kwale, Kenya. PLoS Negl Trop Dis, 2017; 11(9): e0005872.
Deloer S, Nakamura R, Kikuchi M, Moriyasu T, Kalenda YDJ, Mohammed ES, Senba M, Iwakura Y, Yoshida H, Hamano S: IL-17A contributes to reducing IFN-γ/IL-4 ratio and persistence of Entamoeba histolytica during intestinal amebiasis. Parasitol Int, 2017; 66(6): 817-823.
安達圭司・濱野真二郎：One Healthの視点からみた寄生虫感染症、「特集 One Healthの視点からみた感染症の現状と対策」、最新醫學、2017; 70(11): 2407-2414.
濱野真二郎：吸虫症、内科学 第11版、2017; 354-360.
濱野真二郎：リーシュマニア症、今日の治療指針、2017; 59: 241-243.
Hamano, S. and William A. Petri Jr.: Chapter 209: Amoebiasis in “Feigin, Cherry, Demmler, Kaplan: Textbook of Pediatric Infectious Disease, 8th edition” , 2017; 8: 2118-2123.
2016年
Nzou SM, Fujii Y, Miura M, Mwau M, Mwangi AW, Itoh M, Salam MA, Hamano S, Hirayama K, Kaneko S: Development of multiplex serological assay for the detection of human African trypanosomiasis. Parasitol Int, 2016; 65(2): 121-127.
Mi-ichi F, Yoshida H, Hamano S: Entamoeba encystation: new targets to prevent the transmission of amebiasis. PLoS Pathogens, 2016, 12(10): e1005845.
Ghosh P, Bhaskar KR, Hossain F, Khan MA, Vallur AC, Duthie MS, Hamano S, Salam MA, Huda MM, Khan MG, Coler RN, Reed SG, Mondal D: Evaluation of diagnostic performance of rK28 ELISA using urine for diagnosis of visceral leishmaniasis. Parasit Vectors, 2016; 9(1): 383.
Mitsui Y: Development of a simple and specific direct competitive ELISA for the determination of artesunate using an anti-artesunate polyclonal antiserum. Trop Med Health, 2016; 44: 37.
Hasnain MG, Shomik MS, Ghosh P, Rashid MO, Hossain MS, Hamano S, Mondal D: Post kala-azar dermal leishmaniasis without previous history of visceral leishmaniasis. Am J Trop Med Hyg, 2016; 95(6): 1383-1385.
Mondal D, Hasnain MG, Hossain MS, Ghosh D, Ghosh P, Hossain H, Baker J, Nath R, Haque R, Matlashewski G, Hamano S: Study on the safety and efficacy of miltefosine for the treatment of children and adolescents with post-kala-azar dermal leishmaniasis in Bangladesh, and an association of serum vitamin E and exposure to arsenic with post-kala-azar dermal leishmaniasis: an open clinical trial and case-control study protocol. BMJ Open, 2016; 6(5): e010050.
Deloer S, Nakamura R, Mi-Ichi F, Adachi K, Kobayashi S, Hamano S: Mouse models of amoebiasis and culture methods of amoeba. Parasitol Int, 2016; 65(5 Pt B): 520-525.
Bao LQ, Nhi DM, Huy NT, Kikuchi M, Yanagi T, Hamano S, Hirayama K: Splenic CD11c+ cells derived from semi-immune mice protect naive mice against experimental cerebral malaria. Malar J, 2015; 14(1): 23.
Kalenda YD, Kato K, Goto Y, Fujii Y, Hamano S: Tandem repeat recombinant proteins as potential antigens for the sero-diagnosis of Schistosoma mansoni infection. Parasitol Int, 2015; 64(6): 503-512.
Tanigawa C, Fujii Y, Miura M, Nzou SM, Mwangi AW, Nagi S, Hamano S, Njenga SM, Mbanefo EC, Hirayama K, Mwau M, Kaneko S: Species-specific serological detection for schistosomiasis by serine protease inhibitor (SERPIN) in multiplex assay. PLoS Negl Trop Dis, 2015; 9(8): e4021.
Kato K, Yahata K, Dhoubhadel BG, Fujii Y, Tachibana H: Novel hemagglutinating, hemolytic and cytotoxic activities of the intermediate subunit of Entamoeba histolytica lectin. Sci Rep, 2015; 5: e13901.
