長崎大学 熱帯医学研究所 病原体解析部門 原虫学分野 金子

 金子 修, MD, PhD

業績など

原著論文
【マラリア原虫の赤血球侵入・感染赤血球の接着現象の分子機構】


Zhu X, He Y, Liang Y, Kaneko O, Cui L, Cao Y. Tryptophan-rich domains of Plasmodium falciparum SURFIN4.2 and Plasmodium vivax PvSTP2 interact with membrane skeleton of red blood cell. Malar J 16(1):121 (2017/03) [Abstract].

Li J, Pattaradilokrat S, Zhu F, Jiang H, Liu S, Hong L, Fu Y, Koo L, Xu W, Pan W, Carlton JM, Kaneko O, Carter R, Wootton JC, Su XZ. Linkage maps from multiple genetic crosses and loci linked to growth-related virulent phenotype in Plasmodium yoelii. Proc Natl Acad Sci USA 108(31):E374-82 (2011/08) [Abstract].

Alexandre JSF, Yahata K, Kawai S, Torii M, Kaneko O. PEXEL-independent trafficking of Plasmodium falciparum SURFIN4.2 to the parasite-infected red blood cell and Maurer's clefts. Parasitol Int 60:313-20 (2011/09) [Abstract]

Otsuki H, Kaneko O, Thongkukiatkul A, Tachibana M, Iriko H, Takeo S, Tsuboi T, Torii M. Single amino acid substitution in Plasmodium yoelii erythrocyte ligand determines its localization and controls parasite virulence. Proc Natl Acad Sci USA 106(17):7167-72 (2009/04) [Abstract]

Iriko H, Jin L, Kaneko O, Takeo S, Han E-T, Tachibana M, Otsuki H, Torii M, Tsuboi T, A small-scale systematic analysis of alternative splicing in Plasmodium falciparum. Parasitol Int 58:196-9 (2009/06) [Abstract]

Cao J, Kaneko O, Thongkukiatkul A, Tachibana M, Otsuki H, Gao Q, Tsuboi T, Torii M. Rhoptry neck protein RON2 forms a complex with microneme protein AMA1 in Plasmodium falciparum merozoites. Parasitol Int 58:29-35 (2009/03) [Abstract]

Mphande FA, Ribacke U, Kaneko O, Kironde F, Winter G, Wahlgren M. SURFIN4.1, a schizont-merozoite associated protein in the SURFIN family of Plasmodium falciparum. Malaria J 7:116 (2008/07) [Abstract] [Open Access]

Iriko H, Kaneko O, Otsuki H, Tsuboi T, Su XZ, Tanabe K, Torii M.  Diversity and evolution of the rhoph1/clag multigene family of Plasmodium falciparum. Mol Biochem Parasitol 158(1):11-21 (2008/03) [Abstract]

Cortés A, Carret C, Kaneko O, Yim-Lim BYS, Ivens A, Holder AA.  Epigenetic silencing of Plasmodium falciparum genes linked to erythrocyte invasion. PLoS Pathog 3:e107 (2007/08) [Abstract] [Open Access]

Moll K, Chene A, Ribacke U, Kaneko O, Nilsson S, Winter G, Haeggstrom M, Pan W, Berzins K, Wahlgren M, Chen Q. A novel DBL-domain of the P. falciparum 332 molecule involved in erythrocyte adhesion. PLoS ONE 2:e477 (2007/05) [Abstract] [Open Access]

Ghoneim A, Kaneko O, Tsuboi T, Torii M.  The Plasmodium falciparum RhopH2 promoter and first 24 amino acids are sufficient to target proteins to the rhoptries. Parasitol Int 56(1):31-43 (2007/03) [Abstract]

Kaneko O, Yim-Lim BYS, Iriko H, Ling IT, Otsuki H, Grainger M, Tsuboi T, Adams JH, Mattei D, Holder AA, Torii M. Apical expression of three RhopH1/Clag proteins as components of the Plasmodium falciparum RhopH complex. Mol Biochem Parasitol 143(1):20-28 (2005/09).
[Abstract]

Winter G, Kawai S, Haeggstrom M, Kaneko O, von Euler A, Kawazu S, Palm D, Fernandez V, Wahlgren M. SURFIN is a polymorphic antigen expressed on Plasmodium falciparum merozoites and infected erythrocytes. J Exp Med 201(11):1853-63 (2005/06). [Abstract]

Rungruang T, Kaneko O, Murakami Y, Tsuboi T, Hamamoto H, Akimitsu N, Sekimizu K, Kinoshita T, Torii M. Erythrocyte surface glycosylphosphatidyl inositol anchored receptor for the malaria parasite. Mol Biochem Parasitol 140(1):13-21 (2005/03). [Abstract]

Preiser P, Renia L, Singh N, Balu B, Jarra W, Voza T, Kaneko O, Blair P, Torii M, Landau I, Adams JH. Antibodies against MAEBL ligand domains M1 and M2 inhibit sporozoite development in vitro.  Infect Immun 72(6):3604–8 (2004/06) [Abstract] [Full Text]

Ling IT, Florens L, Dluzewski AR, Kaneko O, Grainger M, Yim- Lim BYS, Tsuboi T, Hopkins JM, Johnson JR 3rd, Torii M, Bannister LH, Yates JR, Holder AA and Mattei D. The Plasmodium falciparum clag9 gene encodes a rhoptry protein that is transferred to the host erythrocyte upon invasion. Mol Microbiol 52(1):107-18 (2004/04) [Abstract]

Mayer DC, Mu JB, Kaneko O, Duan J, Su XZ, Miller LH. Polymorphism in the Plasmodium falciparum erythrocyte-binding ligand JESEBL/EBA-181 alters its receptor specificity. Proc Natl Acad Sci USA. 101(8): 2518-23 (2004/02) [Abstract] [Full Text] [PMC Citation]

Ling IT, Kaneko O, Narum D, Tsuboi T, Howell S , Taylor HM, Scott-Finnigan TJ, Torii M, Holder AA. Characterisation of the rhoph2 gene of Plasmodium falciparum and Plasmodium yoelii. Mol Biochem Parasitol 127(1):47-57 (2003/03). [Abstract]

Michon P, Stevens JR, Kaneko O, Adams JH, Evolutionary relationships of conserved cysteine-rich motifs in adhesive molecules of malaria parasites. Mol Biol Evol 19(7):1128-42 (2002/07). [Abstract] [Full Text] [PMC Citation]

Kaneko O, Mu J, Tsuboi T, Su X, Torii M. Gene structure and expression of a Plasmodium falciparum 220-kilodalton protein homologous to the Plasmodium vivax reticulocyte binding proteins. Mol Biochem Parasitol 121(2):275-8 (2002/05). [No Abstract] [PMC Citation]

Kaneko O, Tsuboi T, Ling IT, Howell S, Shirano M, Tachibana M, Cao YM, Holder AA, Torii M. The high molecular mass rhoptry protein, RhopH1, is encoded by members of the clag multigene family in Plasmodium falciparum and Plasmodium yoelii. Mol Biochem Parasitol 118(2):223-31 (2001/12). [Abstract] [PMC Citation]

Mayer DCG, Kaneko O, Hudson-Taylor DE, Reid ME, Miller LH. Characterization of a Plasmodium falciparum erythrocyte binding protein paralogous to EBA-175. Proc Natl Acad Sci USA98(9): 5222-7 (2001/04). [Abstract] [Full Text] [PMC Citation]

Shirano M, Tsuboi T, Kaneko O, Tachibana M, Adams JH, Torii M. Conserved Regions of the Plasmodium yoelii Rhoptry Protein RhopH3 Revealed by Comparison with the P. falciparum Homologue. Mol Biochem Parasitol 112(2): 297-9 (2001/02).  [No Abstract]

Kaneko O, Fidock DA, Schwartz OM, Miller LH. Disruption of the C-terminal region of EBA-175 in the Dd2/Nm clone of Plasmodium falciparum does not affect erythrocyte invasion. Mol Biochem Parasitol 110(1): 135-146 (2000/09). [Abstract] [PMC Citation]

Kaneko O, Soubes SC, Miller LH"Plasmodium falciparum: Invasion of Aotus monkey red blood cells and adaptation to Aotus monkeys"  Exp Parasitol 93(2): 116-119 (1999/10). [No Abstract] [PMC Citation]

Soubes SC, Reid ME, Kaneko O, Miller LH "Search for the Sialic Acid-Independent Receptor on Red Blood Cells for Invasion by Plasmodium falciparum" Vox Sang 76(2): 107-114 (1999). [Abstract]

【マラリア原虫の分子疫学】

Miao M, Wang Z, Yang Z, Yuan L, Parker DM, Putaporntip C, Jongwutiwes S, Xangsayarath P, Pongvongsa T, Moji H, Dinh Tuong T, Abe T, Nakazawa S, Kyaw MP, Yan G, Sirichaisinthop J, Sattabongkot J, Mu J, Su XZ, Kaneko O, Cui L. Genetic Diversity and Lack of Artemisinin Selection Signature on the Plasmodium falciparum ATP6 in the Greater Mekong Subregion. PLoS ONE 8(3):e59192.(2013) [Abstract]

Alexandre JSF, Xangsayarath P, Kaewthamasorn, Yahata K, Sattabongkot J, Udomsangpetch R, Kaneko O. Stable allele frequency distribution of the Plasmodium falciparum clag genes encoding components of the high molecular weight rhoptry protein complex. Trop Med Health 40(3):71-7 (2012/09) [Abstract]

Xangsayarath P, Kaewthamasorn K, Yahata K, Nakazawa S, Sattabongkot J, Udomsangpetch R, Kaneko O. Positive diversifying selection on the Plasmodium falciparum surf4.1 gene in Thailand. Trop Med Health 40(3):79-89 (2012/09) [Abstract]

Kaewthamasorn M, Yahata K, Alexandre JSF, Xangsayarath P, Nakazawa S, Torii M, Sattabongkot J, Udomsangpetch R, Kaneko O. Stable allele frequency distribution of the polymorphic region of SURFIN4.2 in Plasmodium falciparum isolates from Thailand. Parasitol Int 61(2):317-23 (2012/06) [Abstract]

Tang J, Dai Y, Zhang H, Culleton Rl, Liu Y, Zhao S, Wang X, Guan X, Kaneko O, Zhu Y. Positive diversifying selection on Plasmodium vivax RON2 protein. Parasitology 139(6):709-15 (2012/05) [Abstract]

Sungkapong T, Culleton R, Yahata K, Tachibana M, Ruengveerayuth R, Udomsangpetch R, Torii M, Tsuboi T, Sattabongkot J, Kaneko O, Chotivanich K. Humoral immune responses to Plasmodium vivax subtelomeric transmembrane proteins in Thailand.Southeast Asian J Trop Med Public Health 42(6):1313-21 (2011/11) [Abstract]

Alexandre JSF, Kaewthamasorn M, Yahata K, Nakazawa S, Kaneko O. Positive selection on the Plasmodium falciparum clag2 gene encoding a component of the erythrocyte-binding rhoptry protein complex. Trop Med Health 39(3):77-82 (2011). [Abstract]

Tanabe K, Sakihama N, Nakamura Y, Kaneko O, Kimura M, Ferreira MU, Hirayama K "Selection and genetic drift of polymorphisms within the merozoite surface protein-1 gene of Plasmodium falciparum" Gene 241(2): 325-331 (2000/01) [Abstract] [PMC Citation]

Ferreira MU, Liu Q, Kaneko O, Kimura M, Tanabe K, Kimura EAS, Kazin AM, Isomura S, Kawamoto F "Allelic diversity at the merozoite surface protein-1 locus of Plasmodium falciparum in clinical isolates from the southwestern Brazilian Amazon." Am J Trop Med Hyg 59(3): 474-480 (1998/09)[Abstract] [PMC Citation]

Ferreira MU, Liu Q, Zhou M, Kimura M, Kaneko O, Thien HV, Isomura S, Tanabe K, Kawamoto F "Stable patterns of allelic diversity at the Merozoite surface protein-1 locus of Plasmodium falciparum in Clinical isolates from southern Vietnam" J Eukaryot Microbiol 45(1): 131-136 (1998/02) [Abstract] [PMC Citation]

Kaneko O, Kimura M, Kawamoto F, Ferreira MU, Tanabe K "Plasmodium falciparum: Allelic variation in the merozoite surface protein 1 gene in wild isolates from Southern Vietnam" Exp Parasitol 86(1): 45-57 (1997/05) [Abstract] [PMC Citation]

Kaneko O, Jongwutiwes S, Kimura M, Kanbara H, Ishii A, Tanabe K "Plasmodium falciparum: variation in block 4 of the precursor to the major merozoite surface proteins in natural populations." Exp Parasitol 84(1): 92-95 (1996/10) [No Abstract] [PMC Citation]

Kimura M, Kaneko O, Inoue A, Ishii A, Tanabe K "Amplification by polymerase chain reaction of Plasmodium falciparum DNA from Giemsa-stained thin blood smears." Mol Biochem Parasitol 70(1-2): 193-197 (1995/03) [No Abstract] [PMC Citation]

【その他のマラリアに関する研究】

Rapid Identification of Genes Controlling Virulence and Immunity in Malaria Parasites.

Ebine K, Hirai M, Sakaguchi M, Yahata K, Kaneko O, Saito-Nakano Y. Plasmodium Rab5b is secreted to the cytoplasmic face of the tubovesicular network in infected red blood cells together with N-acylated adenylate kinase 2. Malar J 15(1):323 (2016/06) [Abstract]

Sakaguchi M, Miyazaki N, Fujioka H, Kaneko O, Murata K. Three-dimensional analysis of morphological changes in the malaria parasite infected red blood cell by serial block-face scanning electron microscopy. J Struct Biol 193(3):162-71 (2016/03) [Abstract]

Tachibana M, Suwanabun N, Kaneko O, Iriko H, Otsuki H, Sattabongkot J, Kaneko A, Herrera S, Torii M, Tsuboi T. Plasmodium vivax gametocyte proteins, Pvs48/45 and Pvs47, induce transmission-reducing antibodies by DNA immunization. Vaccine 33(16):1901-8 (2015/04) [Abstract]

Abkallo HM, Liu W, Hokama S, Ferreira PE, Nakazawa S, Maeno Y, Quang NT, Kobayashi N, Kaneko O, Huffman MA, Kawai S, Marchand RP, Carter R, Hahn BH, Culleton R. DNA from pre-erythrocytic stage malaria parasites is detectable by PCR in the faeces and blood of hosts. Int J Parasitol 44(7):467-73 (2014/06) [Abstract]

Pattaradilokrat S, Li J, Wu J, Qi Y, Eastman RT, Zilversmit M, Nair SC, Huaman MC, Quinones M, Jiang H, Li N, Zhu J, Zhao K, Kaneko O, Long CA, Su XZ. Plasmodium genetic loci linked to host cytokine and chemokine responses. Genes Immun 15(3):145-52 (2014/04-05) [Abstract]

Zhao H, Konishi A, Fujita Y, Yagi M, Ohata K, Aoshi T, Itagaki S, Sato S, Narita H, Abdelgelil NH, Inoue M, Culleton R, Kaneko O, Nakagawa A, Horii T, Akira S, Ishii KJ, Coban C. Lipocalin 2 bolsters innate and adaptive immune responses to blood-stage malaria infection by reinforcing host iron metabolism. Cell Host Microbe 12(5), 705-16 (2012/11). [Abstract]

Morita M, Sanai H, Hiramoto A, Sato A, Hiraoka O, Sakura T, Kaneko O, Masuyama A, Nojima M, Wataya Y, Kim H-S Plasmodium falciparum endoplasmic reticulum-resident calcium binding protein is a possible target of synthetic antimalarial endoperoxides, N-89 and N-251. J Proteome Res 11(12):5704-11 (2012) [Abstract]

Tachibana S, Sullivan SA, Kawai S, Nakamura S, Kim HR, Goto N, Arisue N, Palacpac NMQ, Honma H, Yagi M, Tougan T, Katakai Y, Kaneko O, Mita T, Kita K, Yasutomi Y, Sutton PL, Shakhbatyan R, Horii T, Yasunaga T, Barnwell JW, Escalante AA, Carlton JM, Tanabe K. Plasmodium cynomolgi genome sequences provide insight into Plasmodium vivax and the monkey malaria clade. Nat Genet 44(9):1051-5 (2012). [Abstract]

Inoue M, Jianxia T, Miyakoda M, Kaneko O, Yui K, Culleton R. The species specificity of immunity generated by live whole organism immunization with erythrocytic and pre-erythrocytic stages of rodent malaria parasites and implications for vaccine development Int J Parasitol 42(9):859-70 (2012). [Abstract]

Tachibana M, Sato C, Otsuki H, Sattabongkot J, Kaneko O, Torii M, Tsuboi T. Plasmodium vivax gametocyte protein Pvs230 is a transmission-blocking vaccine candidate. Vaccine 30(10):1807-12 (2012/02). [Abstract]

Tsumori Y, Ndounga M, Sunahara T, Hayashida N, Inoue M, Nakazawa S, Casimiro P, Isozumi R, Uemura H, Tanabe K, Kaneko O, Culleton R. Plasmodium falciparum: Differential selection of drug resistance alleles in contiguous urban and peri-urban areas of Brazzaville, Republic of Congo. PLoS ONE 6(8), e23430 (2011/08). [Abstract]

Wang Y, Kaneko O, Sattabongkot J, Chen J-H, Lu F, Chai J-Y, Takeo S, Tsuboi T, Ayala FJ, Chen Y, Lim CS, Han ET Genetic Polymorphism of Plasmodium vivax msp1p, a Paralog of Merozoite Surface Protein 1, from Worldwide Isolates. Am J Trop Med Hyg 84(2), 292-297 (2011/02).

Tsuboi T, Takeo S, Iriko H, Jin L, Tsuchimochi M, Matsuda S, Han E-T, Otsuki H, Kaneko O, Sattabongkot J, Udomsangpetch R, Sawasaki T, Torii M, Endo Y. The wheat germ cell-free based production of malaria proteins for discovery of novel vaccine candidates. Infect Immun 76(4):1702-1708 (2008). [Abstract]

Kaneko O, Templeton TJ, Iriko H, Tachibana M, Otsuki H, Takeo S, Sattabongkot J, Torii M, Tsuboi T.  The Plasmodium vivax homolog of the ookinete adhesive micronemal protein, CTRP Parasitol Int55:227-231 (2006). [Abstract]

Tsuboi T, Kaneko O, Cao YM, Tachibana M, Yakushijin Y, Nagao T, Kanbara H, Torii M.  A rapid genotyping method for the vivax malaria transmission-blocking vaccine candidates, Pvs25 and Pvs28.  Parasitol Int 53(3):211–6 (2004/09). [Abstract]

Tsuboi T, Kaneko O, Eitoku C, Suwanabun N, Sattabongkot J, Vinetz JM, Torii M "Gene structure and ookinete expression of the chitinase genes of Plasmodium vivax and Plasmodium yoelii"Mol Biochem Parasitol 130(1):51-4 (2003/03). [No Abstract]

Tachibana M, Tsuboi T, Kaneko O, Khuntirat B, Torii M "Two types of Plasmodium ovale defined by SSU rRNA have distinct sequences for ookinete surface proteins." Mol Biochem Parasitol 122(2):223-6 (2002/07) [No Abstract]

Tachibana M, Tsuboi T, Templeton TJ, Kaneko O, Torii M "Presence of three distince ookinete surface protein genes, Pos25, Pos28-1, and Pos28-2 in Plasmodium ovale."Mol Biochem Parasitol 113(2):341-4 (2001/04) [No Abstract]

Nagao E, Kaneko O, Dvorak JA "Plasmodium falciparum-Infected Erythrocytes: Qualitative and Quantitative Analyses of Parasite-Induced Knobs by Atomic Force Microscopy" J Struct Biol 130(1): 34-44 (2000/05) [Abstract] [PMC Citation]
Kaneko A, Bergqvist Y, Takechi M, Kalkoa M, Kaneko O, Kobayakawa T, Ishizaki T, Bjorkman A "Intrinsic Efficacy of Proguanil Against Falciparum and Vivax Malaria Independent of the Metabolite Cycloguanil" J Infect Dis 179(4): 974-979 (1999/04). [Abstract][Reprint]

Kaneko A, Kaneko O, Taleo G, Bjorkman A, Kobayakawa T "High frequencies of CYP2C19 mutations and poor metabolismof proguanil in Vanuatu." The Lancet 349(9056): 921-922 (1997/03) [No Abstract]

Kimura M, Kaneko O, Liu Q, Zhou M, Kawamoto F, Wataya S, Otani S, Yamaguchi Y, Tanabe K "Identification of the four species of human malaria parasites by nested PCR that targets various sequences in the small subunit rRNA gene" Parasitol Int 46(2): 91-95 (1997/07) [Abstract]

Kawamoto F, Miyake H, Kaneko O, Kimura M, Nguyen TD, Nguyen TD, Liu Q, Zhou M, Le DD, Kawai S, Isomura S, Wataya Y "Sequence variation in the 18S rRNA gene, a target for PCR-based malaria diagnosis, in Plasmodium ovale from southern Vietnam." J Clin Microbiol 34(9): 2287-2289 (1996/09). [Abstract] [Reprint] [PMC Citation]


【その他の研究】

Hakimi H, Yamagishi J, Kegawa Y, Kaneko O, Kawazu SI, Asada M. Establishment of transient and stable transfection systems for Babesia ovata. Parasit Vectors 9:171 (2016/03)

Asada M, Yahata K, Hakimi H, Yokoyama N, Igarashi I, Kaneko O, Suarez CE, Kawazu SI. Transfection of Babesia bovis by double selection with WR99210 and Blasticidin-S and its application for functional analysis of thioredoxin peroxidase-1. PLoS One 10(5):e0125993 (2015/05) [Abstract]

Mossaad E, Asada M, Nakatani D, Inoue N, Yokoyama N, Kaneko O, Kawazu SI. Calcium ions are involved in egress of Babesia bovis merozoites from bovine erythrocytes. J Vet Med Sci. 2014 Oct 7. [Epub ahead of print] [Abstract]

Asada M, Goto Y, Yahata K, Yokoyama N, Kawai S, Inoue N, Kaneko O, Kawazu S-I. Gliding motility of Babesia bovis merozoites visualized by time-lapse video microscopy.PLoS ONE 7(4):e352272012 (2012) [Abstract]

Pandey K, Pandey BD, Mallik AK, Acharya J, Kato K, Kaneko O, Ferreira PE. A new molecular surveillance system for leishmaniasis. Am J Trop Med Hyg  90(6):1082-6 (2014/06) [Abstract]

Pandey BD, Pun SB, Kaneko O, Pandey K, Hirayama K. Expansion of Visceral Leishmaniasis to Western Hilly Part of Nepal. Am J Trop Med Hyg 84(1):107-8 (2011/01). [Abstract]

Pandey K, Pandey BD, Mallik AK, Kaneko O, Uemura H, Kanbara H, Yanagi T, Hirayama K. Diagnosis of visceral leishmaniasis by polymerase chain reaction of DNA extracted from Giemsa’s solution-stained slides. Parasitol Res107(3):727-30 (2010/08) [Abstract]

Pandey BD, Pandey K, Kaneko O, Yanagi T, Hirayama K. Relapse of visceral leishmaniasis following miltefosine treatment in a Nepalese Patient. Am J Trop Med Hyg 80(4):580-2 (2009/04) [Abstract]

Pandey K, Pant S, Kanbara H, Shuaibu MN, MallikAK, Pandey BD, Kaneko O, Yanagi T.  Molecular detection of Leishmania parasites from whole bodies of sandflies collected in Nepal. Parasitol Res 103(2):293-7 (2008). [Abstract]

Katakura K, Fujise H, Takeda K, Kaneko O, Torii M, Suzuki M, Chang KP, Hashiguchi Y "Overexpression of LaMDR2, a novel multidrug resistance ATP-binding cassette transporter, causes 5-fluorouracil resistance in Leishmania amazonensis." FEBS Let 561(1-3):207-12. (2004/03). [Abstract]

総説

Culleton R, Kaneko O. Erythrocyte binding ligands in malaria parasites: Intracellular trafficking and parasite virulence. Acta Tropica 114(3):131-7 (2010/06) [Abstract]

Udomsangpetch R, Kaneko O, Chotivanich K, Sattabongkot J. Cultivation of Plasmodium vivax. Trends Parasitol 24(2):85-8. (2008/02) [Abstract]

Kaneko O.  Erythrocyte invasion: vocabulary and grammar of the Plasmodium rhoptry. Parasitol Int 56(4):255-62 (2007/12). [Abstract]

Adams JH, Kaneko O, Blair PL, Peterson DS. An Expanding ebl Family of Plasmodium falciparum. Trends Parasitol 17(6): 297-9 (2001/06).  [No Abstract] [PMC Citation]

Tsuboi T, Tachibana M, Kaneko O, Torii M "Transmission-blocking vaccine of vivax malaria." Parasitol Int 52(1):1-11 (2003/03). [Abstract]

Tanabe K, Sakihama N, Kaneko O, Saito-Ito A, Kimura M "A PCR method for molecular epidemiology of Plasmodium falciparum Msp-1." Tokai J Exp Clin Med 23(6): 375-81 (1998/12). [Abstract]

Ferreira MU, Kaneko O, Kimura M, Liu Q, Kawamoto F, Tanabe K "Allelic diversity at the merozoite surface protein-1 locus in natural Plasmodium falciparum populations: a brief overview." Mem Inst Oswaldo Cruz, Rio de Janeiro, 93(5): 631-638 (1998/02). [Abstract] [Reprint] [PMC Citation]

著書(和文)

金子修. マラリア原虫への遺伝子導入. マラリア学ラボマニュアル 田辺・脇・小島・北編: 217-227 菜根出版, 東京 (2000).

日本語総説

金子修 『マラリア原虫の赤血球認識と侵入の駆動力』 実験医学 27(10): 117-122 (2009/06). [Abstract]

坪井敬文、竹尾暁、入子英幸、金子修、鳥居本美、遠藤弥重太 『コムギ胚芽無細胞タンパク質合成法:マラリアワクチン研究への応用』 愛媛医学 26(1): 8-11 (2007/03).

金子修、大槻均、入子英幸、坪井敬文、鳥居本美 『マラリア原虫の赤血球侵入に関わる多重遺伝子族』 愛媛医学 22(2): 102-9 (2003/06) [PDF file, 6MB]

その他(Proceedingsなど)

Kaneko O, Rungruang T, Tsuboi T, Torii M "Review: Identification of Plasmodium yoelii rhoph2 gene." Proceedings of the 9th Korea-Japan Parasitologists' Seminar 2003.Oct.28-30: p20-26 (2003). [PDF]

Tsuboi T, Cao YM, Rungruang T, Otsuki H, Iriko H, Kaneko O, Sattabongkot J, Torii M "Recent progress on transmission-blocking vaccine development of vivax malaria." Proceedings of the 8th Korea-Japan Parasitologists' Seminar 2002.Oct.5-7 (Maebashi, Japan): p66-73

Kaneko O, Tsuboi T, Rungruang T, Torii M "Characterization of the high molecular mass rhoptry protein, RhopH, complex, in Plasmodium yoelii." Proceedings of the 7th Korea-Japan Parasitologists' Seminar 2001.Oct.23-25: p76-85 (2001). [PDF]

学会活動/社会活動など

1994年−
日本寄生虫学会 会員(2005年4月より評議員)
1996年11月29日
日本熱帯医学会 会員(2009年1月より評議員, 2009年1月-2011年12月:監事)
2003年10月−
American Society of Tropical Medicine and Hygiene 終世会員
2012年4月−
日米医学協力研究会・寄生虫疾患専門部会 研究協力者
2009年4月−
分子寄生虫・マラリア研究フォーラム 世話人
2012年2月-
感染症若手フォーラム 実行委員
2013年8月-
NIAID/ICEMR program SAG member (科学諮問委員)
 過去の活動
2004年8月−2006年8月
分子寄生虫学ワークショップ 世話人
2002年4月−2007年3月
日米医学協力研究会・寄生虫疾患専門部会 共同研究員
2003年6月−2009年12月
共立出版社「蛋白質核酸酵素」Affiliate
2006年9月−2009年11月
ATCC/MR4 SAC member (科学諮問委員)
2006年2月−2011年2月
感染症沖縄フォーラム 実行委員
2009年8月−2011年7月
文部科学省学術調査官(科学研究費補助金担当)(非常勤)
2007年4月−2012年3月
日米医学協力研究会・寄生虫疾患専門部会 分担研究員

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