業績など
原著論文
【マラリア原虫の赤血球侵入・感染赤血球の接着現象の分子機構】
 Zhu X, He Y, Liang Y, Kaneko O, Cui L, Cao Y. Tryptophan-rich domains of Plasmodium falciparum SURFIN4.2 and Plasmodium vivax PvSTP2 interact with membrane skeleton of red blood cell. Malar J 16(1):121 (2017/03) [Abstract].
Li J, Pattaradilokrat S, Zhu F, Jiang H, Liu S, Hong L, Fu Y, Koo L, Xu W, Pan W, Carlton JM, Kaneko O, Carter R, Wootton JC, Su XZ. Linkage maps from multiple genetic crosses and loci linked to growth-related virulent phenotype in Plasmodium yoelii. Proc Natl Acad Sci USA 108(31):E374-82 (2011/08) [Abstract].
Alexandre JSF, Yahata K, Kawai S, Torii M, Kaneko O. PEXEL-independent trafficking of Plasmodium falciparum SURFIN4.2 to the parasite-infected red blood cell and Maurer's clefts. Parasitol Int 60:313-20 (2011/09) [Abstract]
Otsuki H, Kaneko O, Thongkukiatkul A, Tachibana M, Iriko H, Takeo S, Tsuboi T, Torii M. Single amino acid substitution in Plasmodium yoelii erythrocyte ligand determines its localization and controls parasite virulence. Proc Natl Acad Sci USA 106(17):7167-72 (2009/04) [Abstract]
Iriko H, Jin L, Kaneko O, Takeo S, Han E-T, Tachibana M, Otsuki H, Torii M, Tsuboi T, A small-scale systematic analysis of alternative splicing in Plasmodium falciparum. Parasitol Int 58:196-9 (2009/06) [Abstract]
Cao J, Kaneko O, Thongkukiatkul A, Tachibana M,
Otsuki H, Gao Q, Tsuboi T, Torii M. Rhoptry neck protein RON2 forms a complex with microneme protein AMA1 in Plasmodium falciparum merozoites. Parasitol Int 58:29-35 (2009/03) [Abstract]
Mphande FA, Ribacke U, Kaneko O, Kironde F, Winter G, Wahlgren M. SURFIN4.1, a schizont-merozoite associated protein in the SURFIN family of Plasmodium falciparum. Malaria J 7:116 (2008/07) [Abstract] [Open Access]
Iriko H, Kaneko O, Otsuki H, Tsuboi T, Su XZ, Tanabe K, Torii M.
Diversity and evolution of the rhoph1/clag multigene family
of Plasmodium falciparum. Mol
Biochem Parasitol 158(1):11-21 (2008/03) [Abstract]
Cortés A, Carret
C, Kaneko O, Yim-Lim BYS, Ivens A, Holder AA.
Epigenetic silencing of Plasmodium falciparum genes linked to
erythrocyte invasion. PLoS Pathog 3:e107 (2007/08) [Abstract] [Open Access]
Moll K, Chene A,
Ribacke U, Kaneko O, Nilsson S, Winter G, Haeggstrom M, Pan W,
Berzins K, Wahlgren M, Chen Q. A novel DBL-domain of the P. falciparum 332
molecule involved in erythrocyte adhesion. PLoS ONE 2:e477
(2007/05) [Abstract] [Open Access]
Ghoneim A, Kaneko O, Tsuboi T, Torii M. The Plasmodium falciparum RhopH2 promoter and first 24 amino acids are sufficient to target
proteins to the rhoptries. Parasitol Int 56(1):31-43 (2007/03) [Abstract]
Kaneko O, Yim-Lim
BYS, Iriko H, Ling IT, Otsuki H, Grainger M, Tsuboi T, Adams JH,
Mattei D, Holder AA, Torii M. Apical
expression of three RhopH1/Clag proteins as components of the Plasmodium falciparum RhopH complex. Mol
Biochem Parasitol 143(1):20-28 (2005/09).
[Abstract]
Winter G, Kawai
S, Haeggstrom M, Kaneko O, von Euler A,
Kawazu S, Palm D, Fernandez V, Wahlgren M. SURFIN is a
polymorphic antigen expressed on Plasmodium falciparum merozoites and infected erythrocytes. J
Exp Med 201(11):1853-63 (2005/06). [Abstract]
Rungruang T, Kaneko O, Murakami Y, Tsuboi T, Hamamoto H, Akimitsu N, Sekimizu K, Kinoshita T, Torii M. Erythrocyte
surface glycosylphosphatidyl inositol anchored receptor for the
malaria parasite. Mol
Biochem Parasitol 140(1):13-21 (2005/03). [Abstract]
Preiser P, Renia L, Singh N, Balu B, Jarra W, Voza T, Kaneko O, Blair P, Torii M, Landau I, Adams JH. Antibodies against MAEBL
ligand domains M1 and M2 inhibit sporozoite development in vitro. Infect Immun 72(6):3604–8
(2004/06) [Abstract] [Full Text]
Ling IT, Florens L, Dluzewski AR, Kaneko O, Grainger M, Yim- Lim BYS, Tsuboi T, Hopkins
JM, Johnson JR 3rd, Torii M, Bannister LH, Yates JR, Holder AA and Mattei D. The Plasmodium falciparum clag9 gene encodes a rhoptry protein that is transferred to the host erythrocyte upon invasion. Mol Microbiol 52(1):107-18 (2004/04) [Abstract]
Mayer DC, Mu JB, Kaneko O, Duan J, Su XZ, Miller LH. Polymorphism in the Plasmodium falciparum erythrocyte-binding ligand JESEBL/EBA-181
alters its receptor specificity. Proc Natl Acad Sci USA. 101(8): 2518-23 (2004/02) [Abstract] [Full Text] [PMC
Citation]
Ling IT, Kaneko O, Narum D, Tsuboi T, Howell S , Taylor HM, Scott-Finnigan TJ, Torii M, Holder AA. Characterisation of the rhoph2 gene of Plasmodium falciparum and Plasmodium yoelii. Mol Biochem Parasitol 127(1):47-57
(2003/03). [Abstract]
Michon P, Stevens JR, Kaneko O, Adams JH, Evolutionary relationships of conserved cysteine-rich
motifs in adhesive molecules of malaria parasites. Mol Biol Evol 19(7):1128-42 (2002/07). [Abstract] [Full Text] [PMC
Citation]
Kaneko O, Mu J, Tsuboi T, Su X, Torii M. Gene structure and expression of a Plasmodium falciparum 220-kilodalton protein homologous to the Plasmodium vivax reticulocyte
binding proteins. Mol Biochem Parasitol 121(2):275-8 (2002/05). [No
Abstract] [PMC
Citation]
Kaneko O, Tsuboi T, Ling IT, Howell S, Shirano M, Tachibana M, Cao YM,
Holder AA, Torii M. The high molecular mass rhoptry protein, RhopH1, is encoded by members of the clag multigene family in Plasmodium falciparum and Plasmodium yoelii.
Mol Biochem Parasitol 118(2):223-31 (2001/12).
[Abstract]
[PMC
Citation]
Mayer DCG, Kaneko O, Hudson-Taylor DE, Reid ME, Miller LH. Characterization of a Plasmodium falciparum
erythrocyte binding protein paralogous to EBA-175. Proc Natl Acad Sci USA. 98(9): 5222-7 (2001/04).
[Abstract]
[Full
Text]
[PMC
Citation]
Shirano M, Tsuboi T, Kaneko O, Tachibana M, Adams JH, Torii M. Conserved Regions of the Plasmodium yoelii Rhoptry Protein RhopH3 Revealed by Comparison with the P. falciparum
Homologue. Mol Biochem Parasitol 112(2): 297-9
(2001/02).
[No Abstract]
Kaneko O, Fidock DA, Schwartz OM, Miller LH. Disruption of the C-terminal region of EBA-175 in the Dd2/Nm clone of Plasmodium falciparum
does not affect erythrocyte invasion. Mol Biochem Parasitol 110(1): 135-146 (2000/09).
[Abstract]
[PMC
Citation]
Kaneko O,
Soubes SC, Miller LH"Plasmodium falciparum: Invasion of Aotus
monkey red blood cells and adaptation to Aotus monkeys" Exp Parasitol 93(2):
116-119 (1999/10).
[No Abstract] [PMC Citation]
Soubes SC, Reid ME, Kaneko O, Miller LH
"Search for the Sialic Acid-Independent Receptor on Red Blood Cells for
Invasion by Plasmodium falciparum" Vox Sang 76(2):
107-114 (1999).
[Abstract]
【マラリア原虫の分子疫学】
Nundu SS, Culleton R, Simpson SV, Arima H, Chitama BYA, Muyembe JJ, Ahuka S, Kaneko O, Mita T, Yamamoto T. Identification of polymorphisms in genes associated with drug resistance in Plasmodium falciparum isolates from school-age children in Kinshasa, Democratic Republic of Congo . Parasitol Int (in press)
Osborne A, Manko E, Takeda M, Kaneko A, Kagaya W, Chan C, Ngara M, Kongere J, Kita K, Campino S, Kaneko O, Gitaka J, Clark TG. Characterizing the genomic variation and population dynamics of Plasmodium falciparum malaria parasites in and around Lake Victoria, Kenya. Sci Rep 11:19809. (2021/10) [PubMed] doi: 10.1038/s41598-021-99192-1
Miao M, Wang Z, Yang Z, Yuan L, Parker DM, Putaporntip C, Jongwutiwes S, Xangsayarath P, Pongvongsa T, Moji H, Dinh Tuong T, Abe T, Nakazawa S, Kyaw MP, Yan G, Sirichaisinthop J, Sattabongkot J, Mu J, Su XZ, Kaneko O, Cui L. Genetic Diversity and Lack of Artemisinin Selection Signature on the Plasmodium falciparum ATP6 in the Greater Mekong Subregion. PLoS ONE 8(3):e59192.(2013) [Abstract]
Alexandre JSF, Xangsayarath P, Kaewthamasorn, Yahata K, Sattabongkot J, Udomsangpetch R, Kaneko O. Stable allele frequency distribution of the Plasmodium falciparum clag genes encoding components of the high molecular weight rhoptry protein complex. Trop Med Health 40(3):71-7 (2012/09) [Abstract]
Xangsayarath P, Kaewthamasorn K, Yahata K, Nakazawa S, Sattabongkot J, Udomsangpetch R, Kaneko O. Positive diversifying selection on the Plasmodium falciparum surf4.1 gene in Thailand. Trop Med Health 40(3):79-89 (2012/09) [Abstract]
Kaewthamasorn M, Yahata K, Alexandre JSF, Xangsayarath P, Nakazawa S, Torii M, Sattabongkot J, Udomsangpetch R, Kaneko O. Stable allele frequency distribution of the polymorphic region of SURFIN4.2 in Plasmodium falciparum isolates from Thailand. Parasitol Int 61(2):317-23 (2012/06) [Abstract]
Tang J, Dai Y, Zhang H, Culleton Rl, Liu Y, Zhao S, Wang X, Guan X, Kaneko O, Zhu Y. Positive diversifying selection on Plasmodium vivax RON2 protein. Parasitology 139(6):709-15 (2012/05) [Abstract]
Sungkapong T, Culleton R, Yahata K, Tachibana M, Ruengveerayuth R, Udomsangpetch R, Torii M, Tsuboi T, Sattabongkot J, Kaneko O, Chotivanich K. Humoral immune responses to Plasmodium vivax subtelomeric transmembrane proteins in Thailand.Southeast Asian J Trop Med Public Health 42(6):1313-21 (2011/11) [Abstract]
Alexandre JSF, Kaewthamasorn M, Yahata K, Nakazawa S, Kaneko O. Positive selection on the Plasmodium falciparum clag2 gene encoding a component of the erythrocyte-binding rhoptry protein complex. Trop Med Health 39(3):77-82 (2011). [Abstract]
Tanabe K, Sakihama N, Nakamura Y, Kaneko O, Kimura M, Ferreira MU, Hirayama K
"Selection and genetic drift of polymorphisms within the merozoite surface protein-1 gene of Plasmodium falciparum"
Gene 241(2): 325-331 (2000/01)
[Abstract]
[PMC Citation]
Ferreira MU, Liu Q, Kaneko O, Kimura M, Tanabe K, Kimura EAS, Kazin AM, Isomura S, Kawamoto F "Allelic diversity at the merozoite surface protein-1 locus
of Plasmodium falciparum in clinical isolates from the southwestern Brazilian Amazon." Am J Trop Med Hyg 59(3): 474-480 (1998/09)[Abstract]
[PMC Citation]
Ferreira MU, Liu Q, Zhou M, Kimura M, Kaneko O, Thien
HV, Isomura S, Tanabe K, Kawamoto F "Stable patterns of allelic diversity at the Merozoite surface
protein-1 locus of Plasmodium falciparum in Clinical isolates from
southern Vietnam" J Eukaryot Microbiol 45(1): 131-136 (1998/02)
[Abstract]
[PMC Citation]
Kaneko O,
Kimura M, Kawamoto F, Ferreira MU, Tanabe K "Plasmodium falciparum: Allelic variation in the merozoite
surface protein 1 gene in wild isolates from Southern Vietnam"
Exp Parasitol 86(1): 45-57
(1997/05) [Abstract]
[PMC
Citation]
Kaneko O, Jongwutiwes S, Kimura M, Kanbara H, Ishii A, Tanabe K "Plasmodium falciparum: variation in block 4 of the
precursor to the major merozoite surface proteins in natural populations."
Exp Parasitol
84(1): 92-95 (1996/10) [No Abstract]
[PMC
Citation]
Kimura M,
Kaneko O, Inoue A, Ishii A, Tanabe K "Amplification by polymerase chain reaction of Plasmodium
falciparum DNA from Giemsa-stained thin blood smears." Mol Biochem Parasitol 70(1-2): 193-197
(1995/03) [No Abstract]
[PMC Citation]
【その他のマラリアに関する研究】
Christensen P, Racklyeft A, Ward KE, Matheson J, Suwanarusk R, Chua ACY, Kaneko O, Aung HL, Renia L, Amanzougaghene, Magneron V, Lemaitre J, Le Grand R, Kyle D, Bifani P, Cook GM, Snounou G, Russell B. Improving in vitro continuous cultivation of Plasmodium cynomolgi, a model for P. vivax. Parasitol Int 102589. (2022/04) [PubMed] doi: 10.1016/j.parint.2022.102589
Nugraheni YR, Arnuphapprasert A, Nguyen TT, Narapakdeesakul D, Nguyen HLA, Poofery J, Kaneko O, Asada M, Kaewthamasorn M. Myzorhynchus series of Anopheles mosquitoes as potential vectors of Plasmodium bubalis in Thailand. Sci Rep 5747. (2022/04) [PubMed] doi: 10.1038/s41598-022-09686-9
Sulistyowaty MI, Uyen NH, Suganuma K, Chitama BYA, Yahata K, Kaneko O, Sugimoto S, Yamano Y, Kawakami S, Otsuka H, Matsunami K. Six new phenylpropanoid derivatives from chemically converted extract of Alpinia galanga (L.) and anti-parasitic activities. Molecules 26(6):1756 (2021/03) [PubMed] doi: 10.3390/molecules26061756
Teklemichael AA, Mizukami S, Toume K, Mosaddeque F, Kamel MG, Kaneko O, Komatsu K, Karbwang J, Huy NT, Hirayama K. Anti-malarial activity of traditional Kampo medicine Coptis rhizome extract and its major active compounds. Malar J 19: 204 (2020/06) [PubMed] doi: 10.1186/s12936-020-03273-x
Subudhi A, O'Donnel A, Ramaprasad A, Abkallo H, Kaushik A, Ansari H, Mohamed A, Rached F, Kaneko O, Culleton R, Reece S, Pain A. Malaria parasites regulate intra-erythrocytic development duration via serpentine receptor 10 to coordinate with host rhythms. Nat Commun 11:2763 (2020/06) [PubMed] doi: 10.1038/s41467-020-16593-y
Muh F, Nyunt MH, Han JH, Firdaus ER, Hoque MR, Lee SK, Kim N, Park JH, Moon RW, Lau YL, Kaneko O, Han ET. Cross-species reactivity of antibodies against Plasmodium vivax blood-stage antigens to P. knowlesi. PLoS Negl Trop Dis 14(6):e0008323 (2020/06) [PubMed] doi: 10.1371/journal.pntd.0008323
Kawai S, Annoura T, Araki T, Shiogama Y, Shogo S, Sato MO, Kaneko O, Yasutomi Y, Chigusa Y. Development of an effective alternative model for in vivo hypnozoite-induced relapse infections: a Japanese macaque (Macaca fuscata) model experimentally infected with Plasmodium cynomolgi. Parasitol Int 76:102096 (2020/06) [PubMed] doi: 10.1016/j.parint.2020.102096
Kandel RC, Shrestha M, Sadaula A, Khatri-Chhetri M, Maharjan J, Solanki GS, Chalise MK, Asada M, Kaneko O, Poudel RC, Pandey K. First report of the malaria parasite in water buffalo in Nepal. Vet Parasitol Reg Stud Reports 18:100348 (2019/12) [PubMed] doi: 10.1016/j.vprsr.2019.100348
Morita M, Hayashi K, Sato A, Hiramoto A, Kaneko O, Isogawa R, Kurosaki Y, Miyoshi S, Chang KS, Wataya Y, Kim HS. Genomic and biological features of Plasmodium falciparum resistance against antimalarial endoperoxide N-89. Gene 716:144016 (2019/10) [PubMed]
Hakimi H, Sarani A, Takeda M, Kaneko O, Asada M. Epidemiology, risk factors, and co-infection of vector-borne pathogens in goats from Sistan and Baluchestan province, Iran. PLOS ONE 14(6):e0218609 (2019/06) [PubMed]
Ishikawa T,Mizuta S, Kaneko O, Yahata K. Fragment molecular orbital study of the interaction between sarco/endoplasmic reticulum Ca2+-ATPase and its inhibitor thapsigargin toward anti-malarial development. J Phys Chem B122(33):7970-7977 (2018/08) [Abstract]
Muh F, Ahmed MA, Han JH, Nyunt MH, Lee SK, Lau YL, Kaneko O, Han ET. Cross-species analysis of apical asparagine-rich protein of Plasmodium vivax and Plasmodium knowlesi. Sci Rep 8(1):5781 (2018/04) [Abstract]
Mosaddeque F, Mizukami S, Kamel MG, Teklemichael AA, Dat TV, Mizuta S, Toan DV, Ahmed AM, Vuong NL, Elhady MT, Giang HTN, Dang TN, Fukuda M, Huynh LK, Tanaka Y, Egan TJ, Kaneko O, Huy NT, Hirayama K. Prediction model for anti-1 malarial activities of hemozoin inhibitors using physicochemical properties. Antimicrob Agents Chemother 62(5):e02424-17 (2018/04) [Abstract]
Kijogia C, Kimura D, Bao LQ, Nakamura R, Chadeka EA, Cheruiyot NB, Bahati F, Yahata K, Kaneko O, Njenga SM, Ichinose Y, Hamano S, Yui K. Modulation of immune responses by Plasmodium falciparum infection in asymptomatic children living in the endemic region of Mbita, western Kenya. Parasitol Int S1383-5769(17):30518-4 (2018/06) [Abstract]
Ebine K, Hirai M, Sakaguchi M, Yahata K, Kaneko O, Saito-Nakano Y. Plasmodium Rab5b is secreted to the cytoplasmic face of the tubovesicular network in infected red blood cells together with N-acylated adenylate kinase 2. Malar J 15(1):323 (2016/06) [Abstract]
Tachibana M, Suwanabun N, Kaneko O, Iriko H, Otsuki H, Sattabongkot J, Kaneko A, Herrera S, Torii M, Tsuboi T. Plasmodium vivax gametocyte proteins, Pvs48/45 and Pvs47, induce transmission-reducing antibodies by DNA immunization. Vaccine 33(16):1901-8 (2015/04) [Abstract]
Abkallo HM, Liu W, Hokama S, Ferreira PE, Nakazawa S, Maeno Y, Quang NT, Kobayashi N, Kaneko O, Huffman MA, Kawai S, Marchand RP, Carter R, Hahn BH, Culleton R. DNA from pre-erythrocytic stage malaria parasites is detectable by PCR in the faeces and blood of hosts. Int J Parasitol 44(7):467-73 (2014/06) [Abstract]
Pattaradilokrat S, Li J, Wu J, Qi Y, Eastman RT, Zilversmit M, Nair SC, Huaman MC, Quinones M, Jiang H, Li N, Zhu J, Zhao K, Kaneko O, Long CA, Su XZ. Plasmodium genetic loci linked to host cytokine and chemokine responses. Genes Immun 15(3):145-52 (2014/04-05) [Abstract]
Zhao H, Konishi A, Fujita Y, Yagi M, Ohata K, Aoshi T, Itagaki S, Sato S, Narita H, Abdelgelil NH, Inoue M, Culleton R, Kaneko O, Nakagawa A, Horii T, Akira S, Ishii KJ, Coban C. Lipocalin 2 bolsters innate and adaptive immune responses to blood-stage malaria infection by reinforcing host iron metabolism. Cell Host Microbe 12(5), 705-16 (2012/11). [Abstract]
Morita M, Sanai H, Hiramoto A, Sato A, Hiraoka O, Sakura T, Kaneko O, Masuyama A, Nojima M, Wataya Y, Kim H-S Plasmodium falciparum endoplasmic reticulum-resident calcium binding protein is a possible target of synthetic antimalarial endoperoxides, N-89 and N-251. J Proteome Res 11(12):5704-11 (2012) [Abstract]
Tachibana S, Sullivan SA, Kawai S, Nakamura S, Kim HR, Goto N, Arisue N, Palacpac NMQ, Honma H, Yagi M, Tougan T, Katakai Y, Kaneko O, Mita T, Kita K, Yasutomi Y, Sutton PL, Shakhbatyan R, Horii T, Yasunaga T, Barnwell JW, Escalante AA, Carlton JM, Tanabe K. Plasmodium cynomolgi genome sequences provide insight into Plasmodium vivax and the monkey malaria clade. Nat Genet 44(9):1051-5 (2012). [Abstract]
Inoue M, Jianxia T, Miyakoda M, Kaneko O, Yui K, Culleton R. The species specificity of immunity generated by live whole organism immunization with erythrocytic and pre-erythrocytic stages of rodent malaria parasites and implications for vaccine development Int J Parasitol 42(9):859-70 (2012). [Abstract]
Tachibana M, Sato C, Otsuki H, Sattabongkot J, Kaneko O, Torii M, Tsuboi T. Plasmodium vivax gametocyte protein Pvs230 is a transmission-blocking vaccine candidate. Vaccine 30(10):1807-12 (2012/02). [Abstract]
Tsumori Y, Ndounga M, Sunahara T, Hayashida N, Inoue M, Nakazawa S, Casimiro P, Isozumi R, Uemura H, Tanabe K, Kaneko O, Culleton R. Plasmodium falciparum: Differential selection of drug resistance alleles in contiguous urban and peri-urban areas of Brazzaville, Republic of Congo. PLoS ONE 6(8), e23430 (2011/08).
[Abstract]
Wang Y, Kaneko O, Sattabongkot J, Chen J-H, Lu F, Chai J-Y, Takeo S, Tsuboi T, Ayala FJ, Chen Y, Lim CS, Han ET Genetic Polymorphism of Plasmodium vivax msp1p, a Paralog of Merozoite Surface Protein 1, from Worldwide Isolates. Am J Trop Med Hyg 84(2), 292-297 (2011/02).
Tsuboi T, Takeo S, Iriko H, Jin L, Tsuchimochi M, Matsuda S, Han E-T, Otsuki H, Kaneko O, Sattabongkot J, Udomsangpetch R, Sawasaki T, Torii M, Endo Y. The wheat germ cell-free based production of malaria proteins for discovery of novel vaccine candidates. Infect Immun 76(4):1702-1708 (2008). [Abstract]
Kaneko O, Templeton TJ, Iriko H, Tachibana M, Otsuki H, Takeo S, Sattabongkot J, Torii M, Tsuboi T. The Plasmodium vivax homolog of the ookinete adhesive micronemal protein, CTRP Parasitol Int55:227-231 (2006). [Abstract]
Tsuboi T, Kaneko O, Cao YM, Tachibana M, Yakushijin Y, Nagao T, Kanbara H, Torii M. A rapid genotyping method for the vivax malaria transmission-blocking vaccine candidates, Pvs25 and Pvs28. Parasitol Int 53(3):211–6 (2004/09). [Abstract]
Tsuboi T, Kaneko O, Eitoku C, Suwanabun N, Sattabongkot J, Vinetz JM, Torii M "Gene structure and ookinete expression of the chitinase genes of Plasmodium vivax and Plasmodium yoelii"Mol Biochem Parasitol 130(1):51-4 (2003/03). [No Abstract]
Tachibana M, Tsuboi T, Kaneko O, Khuntirat B, Torii M "Two types of Plasmodium ovale defined by SSU rRNA have distinct sequences for ookinete surface proteins." Mol Biochem Parasitol 122(2):223-6 (2002/07) [No Abstract]
Tachibana M, Tsuboi T, Templeton TJ, Kaneko O, Torii M "Presence of three distince ookinete surface protein genes, Pos25, Pos28-1, and Pos28-2 in Plasmodium ovale."Mol Biochem Parasitol 113(2):341-4 (2001/04) [No Abstract]
 Nagao E, Kaneko O, Dvorak JA "Plasmodium falciparum-Infected Erythrocytes: Qualitative and Quantitative Analyses of Parasite-Induced Knobs by Atomic Force Microscopy" J Struct Biol 130(1): 34-44 (2000/05) [Abstract] [PMC Citation] |
Kaneko A, Bergqvist Y, Takechi M, Kalkoa M, Kaneko O, Kobayakawa T, Ishizaki T, Bjorkman
A
"Intrinsic Efficacy of Proguanil Against Falciparum and Vivax Malaria Independent of the Metabolite
Cycloguanil" J Infect Dis 179(4): 974-979 (1999/04). [Abstract][Reprint]
Kaneko A, Kaneko O, Taleo G, Bjorkman A, Kobayakawa T
"High frequencies of CYP2C19 mutations and poor metabolismof proguanil in Vanuatu." The Lancet 349(9056): 921-922 (1997/03) [No Abstract]
Kimura M, Kaneko O, Liu Q, Zhou M, Kawamoto F, Wataya S, Otani
S, Yamaguchi Y, Tanabe K
"Identification of the four species of human malaria parasites
by nested PCR that targets various sequences in the small subunit rRNA gene"
Parasitol Int 46(2): 91-95 (1997/07)
[Abstract]
Kawamoto F, Miyake H, Kaneko O, Kimura M, Nguyen TD, Nguyen TD, Liu Q, Zhou M, Le DD, Kawai S, Isomura S, Wataya
Y
"Sequence variation in the 18S rRNA gene, a target for PCR-based
malaria diagnosis, in Plasmodium ovale from southern Vietnam."
J Clin Microbiol 34(9): 2287-2289
(1996/09).
[Abstract]
[Reprint]
[PMC
Citation]
【その他の研究】
Hakimi H, Templeton TJ, Sakaguchi M, Yamagishi J, Miyazaki S, Yahata K, Uchihashi T, Kawazu S-I, Kaneko O, Asada M. Novel Babesia bovis exported proteins that modify properties of infected red blood cells. PLoS Pathog 16(10): e1008917 (2020/10) [PubMed] doi: 10.1371/journal.ppat.1008917
Hakimi H, Sarani A, Takeda M, Kaneko O, Asada M. Epidemiology, risk factors, and co-infection of vector-borne pathogens in goats from Sistan and Baluchestan province, Iran. PLOS ONE 14(6):e0218609 (2019/06) [PubMed]
Hakimi H, Ishizaki T, Kegawa Y, Kaneko O, Kawazu S, Asada M. Genome editing of Babesia bovis using the CRISPR/Cas9 system. mSphere 4(3):e00109-19 (2019/06) [PubMed]
Asada M, Yahata K, Hakimi H, Yokoyama N, Igarashi I, Kaneko O, Suarez CE, Kawazu SI. Transfection of Babesia bovis by double selection with WR99210 and Blasticidin-S and its application for functional analysis of thioredoxin peroxidase-1. PLOS ONE 10(5):e0125993 (2015/05) [Abstract]
Mossaad E, Asada M, Nakatani D, Inoue N, Yokoyama N, Kaneko O, Kawazu SI. Calcium ions are involved in egress of Babesia bovis merozoites from bovine erythrocytes. J Vet Med Sci. 2014 Oct 7. [Epub ahead of print] [Abstract]
Asada M, Goto Y, Yahata K, Yokoyama N, Kawai S, Inoue N, Kaneko O, Kawazu S-I. Gliding motility of Babesia bovis merozoites visualized by time-lapse video microscopy.PLoS ONE 7(4):e352272012 (2012) [Abstract]
Pandey K, Pandey BD, Mallik AK, Acharya J, Kato K, Kaneko O, Ferreira PE. A new molecular surveillance system for leishmaniasis. Am J Trop Med Hyg 90(6):1082-6 (2014/06) [Abstract]
Pandey BD, Pun SB, Kaneko O, Pandey K, Hirayama K. Expansion of Visceral Leishmaniasis to Western Hilly Part of Nepal. Am J Trop Med Hyg 84(1):107-8 (2011/01). [Abstract]
Pandey K, Pandey BD, Mallik AK, Kaneko O, Uemura H, Kanbara H, Yanagi T, Hirayama K. Diagnosis of visceral leishmaniasis by polymerase chain reaction of DNA extracted from Giemsa’s solution-stained slides. Parasitol Res107(3):727-30 (2010/08) [Abstract]
Pandey BD, Pandey K, Kaneko O, Yanagi T, Hirayama K. Relapse of visceral leishmaniasis after miltefosine treatment in a Nepalese Patient. Am J Trop Med Hyg 80(4):580-2 (2009/04) [Abstract]
Pandey K, Pant S, Kanbara H, Shuaibu MN, MallikAK, Pandey BD, Kaneko O, Yanagi T. Molecular detection of Leishmania parasites from whole bodies of sandflies collected in Nepal.
Parasitol Res 103(2):293-7 (2008). [Abstract]
Katakura K, Fujise H, Takeda K,
Kaneko O, Torii M, Suzuki M, Chang KP, Hashiguchi Y "Overexpression of
LaMDR2, a novel multidrug resistance ATP-binding cassette transporter, causes
5-fluorouracil resistance in Leishmania amazonensis." FEBS
Let 561(1-3):207-12. (2004/03).
[Abstract]
総説
Culleton R, Kaneko O. Erythrocyte binding ligands in malaria parasites: Intracellular trafficking and parasite virulence. Acta Tropica 114(3):131-7 (2010/06) [Abstract]
Udomsangpetch R, Kaneko O, Chotivanich K, Sattabongkot J.
Cultivation of Plasmodium vivax. Trends Parasitol 24(2):85-8. (2008/02) [Abstract]
Kaneko O. Erythrocyte invasion: vocabulary and grammar
of the Plasmodium rhoptry. Parasitol Int 56(4):255-62 (2007/12). [Abstract]
Adams JH, Kaneko O, Blair PL, Peterson DS. An Expanding ebl Family of Plasmodium falciparum. Trends Parasitol 17(6): 297-9 (2001/06). [No Abstract] [PMC Citation]
Tsuboi T, Tachibana M, Kaneko O,
Torii M "Transmission-blocking vaccine of vivax malaria."
Parasitol Int 52(1):1-11
(2003/03).
[Abstract]
Tanabe K, Sakihama N, Kaneko O, Saito-Ito A, Kimura M
"A PCR method for molecular epidemiology of Plasmodium falciparum Msp-1." Tokai J Exp Clin Med 23(6): 375-81 (1998/12).
[Abstract]
Ferreira MU, Kaneko O, Kimura M, Liu Q, Kawamoto F, Tanabe K
"Allelic diversity at the merozoite surface protein-1 locus in natural Plasmodium falciparum populations: a brief overview." Mem Inst Oswaldo Cruz, Rio de Janeiro, 93(5): 631-638 (1998/02).
[Abstract]
[Reprint]
[PMC
Citation]
著書（和文）
金子修. マラリア原虫への遺伝子導入. マラリア学ラボマニュアル
田辺・脇・小島・北編: 217-227 菜根出版, 東京 (2000).
日本語総説
金子修 『マラリア原虫の赤血球認識と侵入の駆動力』 実験医学 27(10): 117-122 (2009/06). [Abstract]
坪井敬文、竹尾暁、入子英幸、金子修、鳥居本美、遠藤弥重太 『コムギ胚芽無細胞タンパク質合成法：マラリアワクチン研究への応用』 愛媛医学 26(1): 8-11 (2007/03).
金子修、大槻均、入子英幸、坪井敬文、鳥居本美 『マラリア原虫の赤血球侵入に関わる多重遺伝子族』 愛媛医学 22(2): 102-9 (2003/06) [PDF file, 6MB]
その他（Proceedingsなど）
Kaneko O, Rungruang T, Tsuboi T, Torii M
"Review: Identification
of
Plasmodium yoelii rhoph2 gene."
Proceedings
of the 9th Korea-Japan Parasitologists' Seminar
2003.Oct.28-30:
p20-26
(2003). [PDF]
Tsuboi T, Cao YM, Rungruang T, Otsuki H, Iriko H, Kaneko O,
Sattabongkot J, Torii M
"Recent progress on
transmission-blocking vaccine development of vivax malaria."
Proceedings
of the 8th Korea-Japan Parasitologists' Seminar
2002.Oct.5-7 (Maebashi, Japan): p66-73
Kaneko O, Tsuboi T, Rungruang T, Torii M
"Characterization of
the high molecular mass rhoptry protein, RhopH, complex, in
Plasmodium yoelii."
Proceedings
of the 7th Korea-Japan Parasitologists' Seminar
2001.Oct.23-25: p76-85
(2001). [PDF]
学会活動/社会活動など
1994年− |
日本寄生虫学会 会員（2005年4月より評議員） |
1996年11月29日 |
日本熱帯医学会 会員（2009年1月より評議員, 2009年1月-2011年12月:監事） |
2003年10月− |
American Society of Tropical Medicine and Hygiene 終世会員 |
2012年4月− |
日米医学協力研究会・寄生虫疾患専門部会 研究協力者 |
2009年4月− |
分子寄生虫・マラリア研究フォーラム 世話人 |
2012年2月- |
感染症若手フォーラム 実行委員 |
2013年8月- |
NIAID/ICEMR program SAG member (科学諮問委員) |
過去の活動 |
|
2004年8月−2006年8月 |
分子寄生虫学ワークショップ 世話人 |
2002年4月−2007年3月 |
日米医学協力研究会・寄生虫疾患専門部会 共同研究員 |
2003年6月−2009年12月 |
共立出版社「蛋白質核酸酵素」Affiliate |
2006年9月−2009年11月 |
ATCC/MR4 SAC member (科学諮問委員) |
2006年2月−2011年2月 |
感染症沖縄フォーラム 実行委員 |
2009年8月−2011年7月 |
文部科学省学術調査官（科学研究費補助金担当）（非常勤） |
2007年4月−2012年3月 |
日米医学協力研究会・寄生虫疾患専門部会 分担研究員
|
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