長崎大学 熱帯医学研究所 病原体解析部門 原虫学分野 矢幡

 

  矢幡 一英, PhD
  助教
鳥取大学農学部農林総合科学科卒業, 1999. [Link]
広島大学大学院理学研究科修士課程修了, 2001. [Link]
大阪大学大学院薬学研究科生命情報環境科学専攻博士課程修了, 2007. [Link]
長崎大学熱帯医学研究所原虫学分野 助教, 2007-現在.
住所   郵便番号852‐8523
長崎市坂本1丁目12‐4
電話/FAX (095)-819-7838 / (095)-819-7805
電子メール  
学術的興味 マラリア
手技手法   細胞生物学・分子生物学
研究テーマ :: 業績

   
研究テーマ

マラリア原虫のエピジェネティクス、トランスフェクション
 

業績

原著論文
Abkallo HM, Martinelli A, Inoue M, Ramaprasad A, Xangsayarath P, Gitaka J, Tang J, Yahata K, Zoungrana A, Mitaka H, Acharjee A, Datta PP, Hunt P, Carter R, Kaneko O, Mustonen V, Illingworth CJR, Pain A, Culleton R. Rapid identification of genes controlling virulence and immunity in malaria parasites. PLoS Pathog 13(7):e1006447 (2017/07) [Abstract].

Gitaka JN, Takeda M, Kimura M, Idris ZM, Chan CW, Kongere J, Yahata K, Muregi FW, Ichinose Y, Kaneko A, Kaneko O. Selections, frameshift mutations, and copy number variation detected on the surf 4.1 gene in the western Kenyan Plasmodium falciparum population. Malar J 16(1):98 (2017/03) [Abstract]

Lucky AB, Sakaguchi M, Katakai Y, Kawai S, Yahata K, Templeton TJ, Kaneko O. Plasmodium knowlesi Skeleton-Binding Protein 1 Localizes to the 'Sinton and Mulligan' Stipplings in the Cytoplasm of Monkey and Human Erythrocytes. PLoS One 11(10):e0164272. (2016/10) [Abstract]

Ebine K, Hirai M, Sakaguchi M, Yahata K, Kaneko O, Saito-Nakano Y. Plasmodium Rab5b is secreted to the cytoplasmic face of the tubovesicular network in infected red blood cells together with N-acylated adenylate kinase 2. Malar J 15(1):323 (2016/06) [Abstract]

Pandey K, Ferreira PE, Ishikawa T, Nagai T, Kaneko O, Yahata K. Ca2+ monitoring in Plasmodium falciparum using the yellow cameleon-Nano biosensor. Sci Rep 6:23454 (2016/03) [Abstract] [Sci Repおすすめコンテンツ選出]

Mutungi JK, Yahata K, Sakaguchi M, Kaneko O. Isolation of invasive Plasmodium yoelii merozoites with a long half-life to evaluate invasion dynamics and potential invasion inhibitors. Mol Biochem Parasitol 204(1):26-33 (2015/12) [Abstract]

Kagaya W, Miyazaki S, Yahata K, Ohta N, Kaneko O. The cytoplasmic region of Plasmodium falciparum SURFIN4.2 is required for transport from Maurer's clefts to the red blood cell surface. Trop Med Health 43(4):265-272 (2015/12)

Kato K, Yahata K, Gopal Dhoubhadel B, Fujii Y, Tachibana H. Novel hemagglutinating, hemolytic and cytotoxic activities of the intermediate subunit of Entamoeba histolytica lectin. Sci Rep 5:13901 (2015/09). [Abstract]

Asada M, Yahata K, Hakimi H, Yokoyama N, Igarashi I, Kaneko O, Suarez CE, Kawazu SI. Transfection of Babesia bovis by double selection with WR99210 and Blasticidin-S and its application for functional analysis of thioredoxin peroxidase-1. PLoS One 10(5):e0125993 (2015/05) [Abstract]

Mutungi JK, Yahata K, Sakaguchi M, Kaneko O. Expression and localisation of rhoptry neck protein 5 in merozoites and sporozoites of Plasmodium yoelii. Parasitol Int 63(6):794-801 (2014/12) [Abstract]

Zhu XT, Yahata K, Alexandre JSF, Tsuboi T, Kaneko O. The N-terminal segment of Plasmodium falciparum SURFIN4.1 is required for its trafficking to the red blood cell cytosol through the endoplasmic reticulum. Parasito Int 62(2):215-29.(2013/04) [Abstract]

Sakura T, Yahata K, Kaneko O. The upstream sequence segment of the C-terminal cysteine-rich domain is required for microneme trafficking of Plasmodium falciparum erythrocyte binding antigen 175. Parasito Int 62(2):157-64.(2013/04) [Abstract]

Yahata K, Treeck M, Culleton R, Gilberger TW, Kaneko O. Time-lapse imaging of red blood cell invasion by the rodent malaria parasite Plasmodium yoelii. PLoS ONE 7(12):e50780 (2012) [Abstract])

Asada M, Goto Y, Yahata K, Yokoyama N, Kawai S, Inoue N, Kaneko O, Kawazu S-I. Gliding motility of Babesia bovis merozoites visualized by time-lapse video microscopy. PLoS ONE 7(4):e35227 (2012). [Abstract]

Kaewthamasorn M, Yahata K, Alexandre JSF, Xangsayarath P, Nakazawa S, Torii M, Sattabongkot J, Udomsangpetch R, Kaneko O. Stable allele frequency distribution of the polymorphic region of SURFIN4.2 in Plasmodium falciparum isolates from Thailand.Parasitol Int 61(2):317-23 (2012/06) [Abstract]

Alexandre JSF, Kaewthamasorn M, Yahata K, Nakazawa S, Kaneko O. Positive selection on the Plasmodium falciparum clag2 gene encoding a component of the erythrocyte-binding rhoptry protein complex. Trop Med Health 39(3):77-82 (2011).[Abstract]

Alexandre JSF, Yahata K, Kawai S, Torii M, Kaneko O. PEXEL-independent trafficking of Plasmodium falciparum SURFIN4.2 to the parasite-infected red blood cell and Maurer's clefts. Parasitol Int 60:313-20 (2011) [Abstract]

Maeshima K, Iino H, Hihara S, Funakoshi T, Watanabe A, Nishimura M, Nakatomi R, Yahata K, Imamoto F, Hashikawa T, Yokota H, Imamoto N. Nuclear pore formation but not nuclear growth is governed by cyclin-dependent kinases (Cdks) during interphase. Nat Struct Mol Biol. 2010 Sep;17(9):1065-71. [Abstract]

Goshima N, Kawamura Y, Fukumoto A, Miura A, Honma R, Satoh R, Wakamatsu A, Yamamoto J, Kimura K, Nishikawa T, Andoh T, Iida Y, Ishikawa K, Ito E, Kagawa N, Kaminaga C, Kanehori K, Kawakami B, Kenmochi K, Kimura R, Kobayashi M, Kuroita T, Kuwayama H, Maruyama Y, Matsuo K, Minami K, Mitsubori M, Mori M, Morishita R, Murase A, Nishikawa A, Nishikawa S, Okamoto T, Sakagami N, Sakamoto Y, Sasaki Y, Seki T, Sono S, Sugiyama A, Sumiya T, Takayama T, Takayama Y, Takeda H, Togashi T, Yahata K, Yamada H, Yanagisawa Y, Endo Y, Imamoto F, Kisu Y, Tanaka S, Isogai T, Imai J, Watanabe S, Nomura N. Human protein factory for converting the transcriptome into an in vitro-expressed proteome. Nat Methods. 2008 Dec;5(12):1011-7. [Abstract]

Wendt KS, Yoshida K, Itoh T, Bando M, Koch B, Schirghuber E, Tsutsumi S, Nagae G, Ishihara K, Mishiro T, Yahata K, Imamoto F, Aburatani H, Nakao M, Imamoto N, Maeshima K, Shirahige K, Peters JM. Cohesin mediates transcriptional insulation by CCCTC-binding factor. Nature. 2008;451(7180):796-801. [Abstract]

Yahata K, Maeshima K, Sone T, Ando T, Okabe M, Imamoto N, Imamoto F. cHS4 insulator-mediated alleviation of promoter interference during cell-based expression of tandemly associated transgenes. J. Mol. Biol. 2007;374(3):580-90. [Abstract]

Funakoshi T, Maeshima K, Yahata K, Sugano S, Imamoto F, Imamoto N. Two distinct human POM121 genes: Requirement for the formation of nuclear pore complexes. FEBS Lett. 2007;581(25):4910-6. [Abstract]

Maeshima K, Yahata K, Sasaki Y, Nakatomi R, Tachibana T, Hashikawa T, Imamoto F, Imamoto N. Cell cycle-dependent dynamics of nuclear pores: pore-free islands and lamins. J. Cell Science. 2006;119:4442-51 [Abstract]

Sasaki Y, Sone T, Yahata K, Kishine H, Hotta J, Chesnut JD, Honda T, Imamoto F. Multi-gene Gateway clone design for expression of multiple heterologous genes in living cells: Eukaryotic clones containing two and three ORF multi-gene cassettes expressed from a single promoter. J. Biotechnol. 2005; Available online June 24, 2005. [Abstract]

Sone T, Yahata K, Sasaki Y, Hotta J, Kishine H, Chesnut JD, Imamoto F. Multi-gene Gateway clone design for expression of multiple heterologous genes in living cells: Modular construction of multiple cDNA expression elements using recombinant cloning. J. Biotechnol. 2005; Available online June 24, 2005. [Abstract]

Yahata K, Kishine H, Sone T, Sasaki Y, Hotta J, Chesnut JD, Okabe M, Imamoto F. Multi-gene Gateway clone design for expression of multiple heterologous genes in living cells: Conditional gene expression at near physiological levels. J. Biotechnol. 2005;118:123-134. [Abstract]

Sasaki Y, Sone T, Yoshida S, Yahata K, Hotta J, Chesnut JD, Honda T, Imamoto F. Evidence for high specificity and efficiency of multiple recombination signals in mixed DNA cloning by the Multisite Gateway system. J. Biotechnol. 2004;107:233-243. [Abstract]

日本語総説

矢幡一英、曽根岳史、今本文男 『タンパク質精製と取り扱いのコツ:タンパク質発現系-Gateway System-』実験医学別冊 144-147 (2007). 羊土社

前島一博、矢幡一英、今本文男、今本尚子 『インスレーター/バウンダリー配列を用いた複数の導入遺伝子を安定的に発現させるシステム』バイオテクノロジージャーナル 7(5); 557-563 (2007). 羊土社

今本文男、曽根岳史、矢幡一英、佐々木ゆかり、高木昌俊、前島一博、今本尚子 『生細胞への複数種cDNAの共導入と発現量の制御』 蛋白質核酸酵素 50(13):1637-1648 (2005) 共立出版社 [No Abstract]


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