Research Associate

Yoshito FUJII, MP, PhD

1993

Graduated Nagasaki University School of Pharmaceutical Science

1995

Master degree: Nagasaki University Graduate School of Pharmaceutical Science.

1997

Pharmacist license.

2003

PhD degree: Nagasaki University Graduate School of Medical Science.

2003
-2004

Researcher: Herman B Wells Center for Pediatric Research, Indiana University

2005-

Research Associate: Institute of Tropical Medicine, Nagasaki University

1)

The regulation of the phagocyte NADPH oxidase and its role in innate immunity

2)

Phagocytosis

3)

Intracellular Pathogens

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Gunasekara D, Fujii Y, Rusvai E, Yoshiie^, Ohashi Nakamaura M .
Human onocytic THP-1 cells upregulate superoxide-generating activity and mRNAs for its components in response to heat-stable and heat-unstable factors of medium conditioned by Ehrlichia chaffeensis-infected cells. Acta Med Nagasaki 49: 39-44, 2004 (acceptedApril 20).

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Fujii Y, Kumatori A, Nakamura M.
SATB1 makes a complex with p300 and represses gp91(phox) promoter activity. Microbiol Immunol. 2003;47(10):803-11.

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Takata-Yahiro M, Fujii Y, Nodarse JF, Islam MR, Oda S, Zhang QM, Yonei S, Nakamura M.
A novel GT-mismatch binding protein that recognizes strict DNA sequences with high affinity. Tohoku J Exp Med. 2003 Aug;200(4):211-229.

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Islam MR, Fan C, Fujii Y, Hao LJ, Suzuki S, Kumatori A, Yang D, Rusvai E, Suzuki N, Kikuchi H, Nakamura M.
PU.1 Is Dominant and HAF-1 Supplementary for Activation of the gp91(phox) Promoter in Human Monocytic PLB-985 Cells. J Biochem (Tokyo). 2002 Apr;131(4):533-40.

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Hao LJ, Yang D, Fujii Y, Yamauchi A, Suzuki N, Kikuchi H, Kaneda Y, Nakamura M.
Phorbol ester-potentiated liposomal transfection to monocytic PLB-985 cells. J Biochem (Tokyo). 2000 Dec;128(6):989-98.

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Yang D, Suzuki S, Hao LJ, Fujii Y, Yamauchi A, Yamamoto M, Nakamura M, Kumatori A. 
Eosinophil-specific regulation of gp91(phox) gene expression by transcription factors GATA-1 and GATA-2. J Biol Chem. 2000 Mar 31;275(13):9425-32.

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Suzuki S, Kumatori A, Haagen IA, Fujii Y, Sadat MA, Jun HL, Tsuji Y, Roos D, Nakamura M. 
PU.1 as an essential activator for the expression of gp91(phox) gene in human peripheral neutrophils, monocytes, and B lymphocytes. Proc Natl Acad Sci U S A. 1998 May 26;95(11):6085-90.