Assistant Professor

Futoshi KURIBAYASHI, MD, PhD


Tel：095-849-7849

Fax：095-849-7848

E-mail：kurikuri@net.nagasaki-u.ac.jp

1991

Graduated Nagasaki University School of Medicine

1991

Medical Doctor

1991

University of Tokyo, Postgraduate School of Medicine

1993

Research Associate: Dept. Bacterial defense, Institute of Medical Science, University of Tokyo

1994

Researcher: The Central Laboratory of the Netherlands Red Cross Blood Transfusion Service and the Laboratory for Experimental and Clinical Immunology of the University of Amsterdam, Holland

1995

Research Associate: Dept. Biochemistry, Kyushu University School of Medicine

1999

Research Associate: Dept. Molecular and Structural Biology, Graduate School of Medical Sciences, Kyushu University

2002

Researcher: Department of Veterinary Biosciences, The Ohio State University, US

2004

Research Associate: Dept. Molecular and Structural Biology, Graduate School of Medical Sciences, Kyushu University

2005

PhD degree

2005

Assistant professor: Department of Host-defense Biochemistry, Institute of Tropical Medicine, Nagasaki University

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The regulation of the phagocyte NADPH oxidase and its role in innate immunity

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Diagnosis of patients with Immunodeficiencies, such as Chronic Granulomatous Disease

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The Japanese Biochemical Society

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Japanese Society for Bacteriology

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Japanese Society for Bio-Defense Research

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The Molecular Biology Society of Japan

1.

Yan Ge, Kiyotaka Yoshiie, Futoshi Kuribayashi, Mingqun Lin, and Yasuko Rikihisa.
Anaplasma phagocytophilum inhibits human neutrophil apoptosis via upregulation of bfl-1, maintenance of mitochondrial membrane potential and prevention of caspase 3 activation.
Cellular Microbiology. 7, 29-38, 2005

2.

Tetsuro Ago, Futoshi Kuribayashi, Hidekazu Hiroaki, Ryu Takeya, Takashi Ito, Daisuke Kohda, and Hideki Sumimoto.
Protein phosphorylation directs PX domain from SH3 domain towards phosphoinositides.
Proc. Natl. Acad. Sci. USA. 100, 4474-4479, 2003

3.

Kaoru Azumi, Futoshi Kuribayashi, Shiro Kanegasaki, and Hideyoshi Yokosawa.
Zymosan induces production of superoxide anions by hemocytes of the solitary ascidian Halocynthia roretzi.
Comp Biochem Physiol C Toxicol Pharmacol. 133, 567-574, 2002

4.

Futoshi Kuribayashi, Hiroyuki Nunoi, Kaori Wakamatsu, Shohko Tsunawaki, Kazuki Sato, Takashi Ito, and Hideki Sumimoto.
The adaptor protein p40(phox) as a positive regulator of the superoxide-producing phagocyte oxidase.
EMBO J. 21, 6312-2630, 2002

5.

Tetsuro Ago, Ryu Takeya, Hidekazu Hiroaki, Futoshi Kuribayashi, Takashi Ito, Daisuke Kohda, and Hideki Sumimoto.
The PX domain as a novel phosphoinositide- binding module.
Biochem Biophys Res Commun. 287, 733-738, 2002

6.

Akira Yamauchi, Lixin Yu, Andy J. G. Potgens, Futoshi Kuribayashi, Hiroyuki Nunoi, Shiro Kanegasaki, Dirk Roos, Harry L. Malech, Mary C. Dinauer, and Michio Nakamura.
Location of the epitope for 7D5, a monoclonal antibody raised against human flavocytochrome b558, to the extracellular peptide portion of primate gp91phox.
Microbiol Immunol. 45, 249-257, 2001

7.

Dongchon Kang, Kenichi Miyako, Futoshi Kuribayashi, Eiji Hasegawa, Athushi Mitsumoto, Tetsuo Nagano, and Koichiro Takeshige.
Changes of energy matabolism induced by 1-Methyl-4-Phenylpyridinium (MPP+) - related compounds in rat pheochromocytoma PC12 cells.
Arch. Biochem. Biophys. 337, 75-80, 1997

8.

Dirk Roos, Martin de Boer, Futoshi Kuribayashi, Christof Meischl, Ron S. Weening, Anthony W. Segal, Anders Ahlin, Katalin Nemet, Johann PeterHossle, Ewa Bernatoeska-Matuszkiewicz, and Helen Middleton-Price.
Mutations in the X-linked and autosomal recessive forms of chronic granulomatous disease.
Blood 87, 1663-1681, 1996

9.

Colin D. Poter, Futoshi Kuribayashi, Mohamed H. Parkar, Dirk Roos, and Christine Kinnon.
Detection of gp91-phox precursor protein in B-cell lines from patients with X-linked chronic granulomatous disease as an indicator mutations impairing cytochrome b558 biosyntesis.
Biochem. J. 315, 571-575, 1996

10.

Futoshi Kuribayashi, Martin de Boer, Jeanette H. Leusen, Arthur J. Verhoeven, and Dirk Roos.
A novel polymorphism in the coding region of CYBB, the human gp91-phox gene.
Human genetics 97, 611-613, 1996

11.

Futoshi Kuribayashi, Shoichi Suzuki, Michio Nakamura, Tdashi Matsumoto, and Yoshiro Tsuji.
Human peripheral eosinophils have a specific mechanism to express gp91-phox, the large subunit of cytochrome b558.
Biochem. Biophys. Res. Commun. 209, 146-152, 1995

12.

Sonoko Kobayashi, Shinobu Imajoh-Ohmi, Futoshi Kuribayashi, Hiroyuki Nunoi, Michio Nakamura, and Shiro Kanegasaki.
Characterization of the superoxide-generating system in human peripheral lymphocytes and lymphoid cell lines.
J. Biochem. 117, 758-765, 1995

13.

Futoshi Kuribayashi, Athushi Kumatori, Shoichi Suzuki, Michio Nakamura, Tadashi Matsumoto, and Yoshiro Tsuji.
A novel type of X-linked chronic granulomatous disease with normal NADPH oxidase activity in eosinophil.
Eur. J. Clin. Invest. 25, A24, 1995

14.

Hidehiko Kikuchi, Taku Fujinawa, Futoshi Kuribayashi, Akira Nakanishi, Shinobu Imajoh-Ohmi, Miki Goto, and Shiro Kanegasaki.
Induction of essential components of the superoxide generating system in human monoblastic leukemia U937 cells.
J. Biochem. 116, 742-746, 1994