Nagasaki Univ   Institute of Tropical Medicine Department of Protozoology Journal Club Recommendation

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Manuscript recommendation

Flueck C, Bartfai R, Volz J, Niederwieser I, Salcedo-Amaya AM, Alako BT, Ehlgen F, Ralph SA, Cowman AF, Bozdech Z, Stunnenberg HG, Voss TS. Plasmodium falciparum heterochromatin protein 1 marks genomic loci linked to phenotypic variation of exported virulence factors. PLoS Pathog. 2009 Sep;5(9):e1000569.

Hohmann-Marriott MF, Sousa AA, Azari AA, Glushakova S, Zhang G, Zimmerberg J, Leapman RD. Nanoscale 3D cellular imaging by axial scanning transmission electron tomography. Nat Methods. 2009 Aug 30. [Epub]

Tripathi AK, Sha W, Shulaev V, Stins MF, Sullivan DJ Jr. Plasmodium falciparum infected erythrocytes induce NF-{kappa}B regulated inflammatory pathways in human cerebral endothelium. Blood. 2009 Aug 27. [Epub]

Howitt CA, Wilinski D, Llinas M, Templeton TJ, Dzikowski R, Deitsch KW. Clonally variant gene families in P. falciparum share a common activation factor. Mol Microbiol. 2009 Aug 24. [Epub]

Tamez PA, Lu H, Fernandez-Pol S, Haldar K, Wickrema A. Stage-specific susceptibility of human erythroblasts to Plasmodium falciparum malaria infection. Blood. 2009 Aug 25. [Epub]

Gordon JL, Buguliskis JS, Buske PJ, Sibley LD. Actin-like protein 1 (ALP1) is a component of dynamic, high molecular weight complexes in Toxoplasma gondii. Cell Motil Cytoskeleton. 2009 Aug 21. [Epub]

Cohen M, Hurtado-Ziola N, Varki A. ABO blood group glycans modulate sialic acid recognition on erythrocytes. Blood. 2009 Aug 24. [Epub]

Ganter M, Schuler H, Matuschewski K. Vital role for the Plasmodium actin capping protein (CP) beta-subunit in motility of malaria sporozoites. Mol Microbiol. 2009 Aug 4. [Epub]

Reese ML, Boothroyd JC. A Helical Membrane-Binding Domain Targets the Toxoplasma ROP2 Family to the Parasitophorous Vacuole. Traffic. 2009 Jun 22. [Epub]

Kebaier C, Vanderberg JP. Initiation of Plasmodium sporozoite motility by albumin is associated with induction of intracellular signaling. Int J Parasitol. 2009 Aug 1. [Epub]

Koncarevic S, Rohrbach P, Deponte M, Krohne G, Helena Prieto J, Yates J 3rd, Rahlfs S, Becker K. The malarial parasite Plasmodium falciparum imports the human protein peroxiredoxin 2 for peroxide detoxification. Proc Natl Acad Sci U S A. 2009 Aug 3. [Epub]

Plassmeyer ML, Reiter K, Shimp RL, Kotova S, Smith PD, Hurt DE, House B, Zou X, Zhang Y, Hickman M, Uchime O, Herrera R, Nguyen V, Glen J, Lebowitz J, Jin AJ, Miller LH, Macdonald NJ, Wu Y, Narum DL. The structure of the Plasmodium falciparum circumsporozoite protein, a leading malaria vaccine candidate. J Biol Chem. 2009 Jul 24. [Epub]

Malhotra I, Dent A, Mungai P, Wamachi A, Ouma JH, Narum DL, Muchiri E, Tisch DJ, King CL. Can prenatal malaria exposure produce an immune tolerant phenotype? A prospective birth cohort study in Kenya. PLoS Med. 2009 Jul;6(7):e1000116. + Hviid L. Unraveling the impact of malaria exposure before birth. PLoS Med. 2009 Jul;6(7):e1000117.

Dondorp AM, Nosten F, Yi P, Das D, Phyo AP, Tarning J, Lwin KM, Ariey F, Hanpithakpong W, Lee SJ, Ringwald P, Silamut K, Imwong M, Chotivanich K, Lim P, Herdman T, An SS, Yeung S, Singhasivanon P, Day NP, Lindegardh N, Socheat D, White NJ. Artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med. 2009 Jul 30;361(5):455-67.

Triglia T, Tham WH, Hodder A, Cowman AF. Reticulocyte binding protein homologues are key adhesins during erythrocyte invasion by Plasmodium falciparum. Cell Microbiol. 2009 Jul 13. [Epub]

Blume M, Rodriguez-Contreras D, Landfear S, Fleige T, Soldati-Favre D, Lucius R, Gupta N. Host-derived glucose and its transporter in the obligate intracellular pathogen Toxoplasma gondii are dispensable by glutaminolysis. Proc Natl Acad Sci U S A. 2009 Jul 17. [Epub]

Kulkarni H, Marconi VC, He W, Landrum ML, Okulicz JF, Delmar J, Kazandjian D, Castiblanco J, Ahuja SS, Wright EJ, Weiss RA, Clark RA, Dolan MJ, Ahuja SK. The Duffy-null state is associated with a survival advantage in leukopenic HIV-infected persons of African ancestry. Blood. 2009 Jul 20. [Epub]

Vanbuskirk KM, O'Neill MT, De La Vega P, Maier AG, Krzych U, Williams J, Dowler MG, Sacci JB Jr, Kangwanrangsan N, Tsuboi T, Kneteman NM, Heppner DG Jr, Murdock BA, Mikolajczak SA, Aly AS, Cowman AF, Kappe SH. Preerythrocytic, live-attenuated Plasmodium falciparum vaccine candidates by design. Proc Natl Acad Sci U S A. 2009 Jul 22. [Epub]

Weiss GE, Crompton PD, Li S, Walsh LA, Moir S, Traore B, Kayentao K, Ongoiba A, Doumbo OK, Pierce SK. Atypical Memory B Cells Are Greatly Expanded in Individuals Living in a Malaria-Endemic Area. J Immunol. 2009 Jul 10. [Epub]

Hodder AN, Malby RL, Clarke OB, Fairlie WD, Colman PM, Crabb BS, Smith BJ. Structural insights into the protease-like antigen Plasmodium falciparum SERA5 and its non-canonical active-site serine. J Mol Biol. 2009 Jul 8. [Epub]

Lozovsky ER, Chookajorn T, Brown KM, Imwong M, Shaw PJ, Kamchonwongpaisan S, Neafsey DE, Weinreich DM, Hartl DL. Stepwise acquisition of pyrimethamine resistance in the malaria parasite. Proc Natl Acad Sci U S A. 2009 Jul 8. [Epub]

John B, Harris TH, Tait ED, Wilson EH, Gregg B, Ng LG, Mrass P, Roos DS, Dzierszinski F, Weninger W, Hunter CA. Dynamic Imaging of CD8(+) T cells and dendritic cells during infection with Toxoplasma gondii. PLoS Pathog. 2009 Jul;5(7):e1000505.

Olivieri A, Camarda G, Bertuccini L, van de Vegte-Bolmer M, Luty AJ, Sauerwein R, Alano P. The Plasmodium falciparum protein Pfg27 is dispensable for gametocyte and gamete production, but contributes to cell integrity during gametocytogenesis. Mol Microbiol. 2009 Jun 30. [Epub]

Cole-Tobian JL, Michon P, Biasor M, Richards JS, Beeson JG, Mueller I, King CL. Strain-Specific Duffy Binding Protein Antibodies Correlate with Protection Against Infection with Homologous Compared to Heterologous Plasmodium vivax Strains in Papua New Guinean Children. Infect Immun. 2009 Jun 29. [Epub]

Bullen HE, Tonkin CJ, O'Donnell RA, Tham WH, Papenfuss AT, Gould S, Cowman AF, Crabb BS, Gilson PR. A novel family Of apicomplexan glideosome associated proteins With an inner-membrane anchoring role. J Biol Chem. 2009 Jun 26. [Epub]

Tung J, Primus A, Bouley AJ, Severson TF, Alberts SC, Wray GA. Evolution of a malaria resistance gene in wild primates. Nature. 2009 Jun 24. [Epub]

Falk N, Kaestli M, Qi W, Ott M, Baea K, Cortes A, Beck HP. Analysis of Plasmodium falciparum var Genes Expressed in Children from Papua New Guinea. J Infect Dis. 2009 Jun 1. [Epub]

Mayor A, Rovira-Vallbona E, Srivastava A, Sharma SK, Pati SS, Puyol L, Quinto L, Bassat Q, Machevo S, Mandomando I, Chauhan VS, Alonso PL, Chitnis CE. Functional and immunological characterization of a Duffy Binding-Like alpha domain from Plasmodium falciparum-erythrocyte membrane protein-1 that mediates rosetting. Infect Immun. 2009 Jun 22. [Epub]

de Koning-Ward TF, Gilson PR, Boddey JA, Rug M, Smith BJ, Papenfuss AT, Sanders PR, Lundie RJ, Maier AG, Cowman AF, Crabb BS. A newly discovered protein export machine in malaria parasites. Nature. 2009 Jun 18;459(7249):945-9. + Reiff SB, Striepen B. Malaria: The gatekeeper revealed. Nature. 2009 Jun 18;459(7249):918-9.

Ollomo B, Durand P, Prugnolle F, Douzery E, Arnathau C, Nkoghe D, Leroy E, Renaud F. A new malaria agent in African hominids. PLoS Pathog. 2009 May;5(5):e1000446.

Jallow M, Teo YY, Small KS, et al; Wellcome Trust Case Control Consortium; Malaria Genomic Epidemiology Network. Genome-wide and fine-resolution association analysis of malaria in West Africa. Nat Genet. 2009 May 24. [Epub]

Hegge S, Kudryashev M, Smith A, Frischknecht F. Automated classification of Plasmodium sporozoite movement patterns reveals a shift towards productive motility during salivary gland infection. Biotechnol J. 2009 May 19. [Epub]

Kishore SP, Perkins SL, Templeton TJ, Deitsch KW. An Unusual Recent Expansion of the C-Terminal Domain of RNA Polymerase II in Primate Malaria Parasites Features a Motif Otherwise Found Only in Mammalian Polymerases. J Mol Evol. 2009 May 16. [Epub]

Ponzi M, Siden-Kiamos I, Bertuccini L, Curra C, Kroeze H, Camarda G, Pace T, Franke-Fayard B, Laurentino EC, Louis C, Waters AP, Janse CJ, Alano P. Egress of Plasmodium berghei gametes from their host erythrocyte is mediated by the MDV-1/PEG3 protein. Cell Microbiol. 2009 Apr 30. [Epub]

Herricks T, Antia M, Rathod PK. Deformability limits of Plasmodium falciparum-infected red blood cells. Cell Microbiol. 2009 Apr 30. [Epub]

Del Carmen MG, Mondragon M, Gonzalez S, Mondragon R. Induction and regulation of conoid extrusion in Toxoplasma gondii. Cell Microbiol. 2009 Mar 16. [Epub]

Tonkin CJ, Carret CK, Duraisingh MT, Voss TS, Ralph SA, Hommel M, Duffy MF, Silva LM, Scherf A, Ivens A, Speed TP, Beeson JG, Cowman AF. Sir2 paralogues cooperate to regulate virulence genes and antigenic variation in Plasmodium falciparum. PLoS Biol. 2009 Apr 14;7(4):e84.

Msellem MI, Martensson A, Rotllant G, Bhattarai A, Stromberg J, Kahigwa E, Garcia M, Petzold M, Olumese P, Ali A, Bjorkman A. Influence of rapid malaria diagnostic tests on treatment and health outcome in fever patients, Zanzibar: a crossover validation study. PLoS Med. 2009 Apr 28;6(4):e1000070. Epub 2009 Apr 28

Desimone TM, Jennings CV, Bei AK, Comeaux C, Coleman BI, Refour P, Triglia T, Stubbs J, Cowman AF, Duraisingh MT. Cooperativity between Plasmodium falciparum adhesive proteins for invasion into erythrocytes. Mol Microbiol. 2009 Apr 14. [Epub]

Kebaier C, Voza T, Vanderberg J. Kinetics of mosquito-injected Plasmodium sporozoites in mice: fewer sporozoites are injected into sporozoite-immunized mice. PLoS Pathog. 2009 Apr;5(4):e1000399.

Duffy MF, Byrne TJ, Carret C, Ivens A, Brown GV. Ectopic recombination of a malaria var gene during mitosis associated with an altered var switch rate. J Mol Biol. 2009 Apr 20. [Epub]

Oleinikov AV, Amos E, Frye IT, Rossnagle E, Mutabingwa TK, Fried M, Duffy PE. High Throughput Functional Assays of the Variant Antigen PfEMP1 Reveal a Single Domain in the 3D7 Plasmodium falciparum Genome that Binds ICAM1 with High Affinity and Is Targeted by Naturally Acquired Neutralizing Antibodies. PLoS Pathog. 2009 Apr;5(4):e1000386.

Combe A, Giovannini D, Carvalho TG, Spath S, Boisson B, Loussert C, Thiberge S, Lacroix C, Gueirard P, Menard R. Clonal conditional mutagenesis in malaria parasites. Cell Host Microbe. 2009 Apr 23;5(4):386-96.

Starnes GL, Coincon M, Sygusch J, Sibley LD. Aldolase Is Essential for Energy Production and Bridging Adhesin-Actin Cytoskeletal Interactions during Parasite Invasion of Host Cells. Cell Host Microbe. 2009 Apr 23;5(4):353-64.

Baum J, Papenfuss AT, Mair GR, Janse CJ, Vlachou D, Waters AP, Cowman AF, Crabb BS, de Koning-Ward TF. Molecular genetics and comparative genomics reveal RNAi is not functional in malaria parasites. Nucleic Acids Res. 2009 Apr 20. [Epub]

Bougdour A, Maubon D, Baldacci P, Ortet P, Bastien O, Bouillon A, Barale JC, Pelloux H, Menard R, Hakimi MA. Drug inhibition of HDAC3 and epigenetic control of differentiation in Apicomplexa parasites. J Exp Med. 2009 Apr 13;206(4):953-66.

Mullapudi N, Joseph S, Kissinger JC. Identification and functional characterization of cis-regulatory elements in the apicomplexan parasite Toxoplasma gondii. Genome Biol. 2009 Apr 7;10(4):R34.

Alkhalil A, Pillai AD, Bokhari AA, Vaidya AB, Desai SA. Complex inheritance of the plasmodial surface anion channel in a Plasmodium falciparum genetic cross. Mol Microbiol. 2009 Mar 6. [Epub]

Ranjan R, Ahmed A, Gourinath S, Sharma P. Dissection of mechanisms involved in the regulation of plasmodium falciparum calcium dependent protein kinase 4 (PfCDPK4). J Biol Chem. 2009 Mar 23. [Epub]

Simon N, Scholz SM, Moreira CK, Templeton TJ, Kuehn A, Dude MA, Pradel G. Sexual stage adhesion proteins form multi-protein complexes in the malaria parasite plasmodium falciparum. J Biol Chem. 2009 Mar 20. [Epub]

Putaporntip C, Hongsrimuang T, Seethamchai S, Kobasa T, Limkittikul K, Cui L, Jongwutiwes S. Differential Prevalence of Plasmodium Infections and Cryptic Plasmodium knowlesi Malaria in Humans in Thailand. J Infect Dis. 2009 Apr 15;199(8):1143-1150. + Collins WE, Barnwell JW. Plasmodium knowlesi: Finally Being Recognized. J Infect Dis. 2009 Apr 15;199(8):1107-8. + Lee KS, Cox-Singh J, Brooke G, Matusop A, Singh B. Plasmodium knowlesi from archival blood films: Further evidence that human infections are widely distributed and not newly emergent in Malaysian Borneo. Int J Parasitol. 2009 Apr 6. [Epub + Galinski MR, Barnwell JW. Monkey malaria kills four humans. Trends Parasitol. 2009 Apr 2. [Epub]

Larkin D, de Laat B, Jenkins PV, Bunn J, Craig AG, Terraube V, Preston RJ, Donkor C, Grau GE, van Mourik JA, O'Donnell JS. Severe Plasmodium falciparum malaria is associated with circulating ultra-large von Willebrand multimers and ADAMTS13 inhibition. PLoS Pathog. 2009 Mar;5(3):e1000349. + de Mast Q, Groot E, Asih PB, Syafruddin D, Oosting M, Sebastian S, Ferwerda B, Netea MG, de Groot PG, van der Ven AJ, Fijnheer R. ADAMTS13 deficiency with elevated levels of ultra-large and active von Willebrand factor in P. falciparum and P. vivax malaria. Am J Trop Med Hyg. 2009 Mar;80(3):492-8.

Gonzalez V, Combe A, David V, Malmquist NA, Delorme V, Leroy C, Blazquez S, Menard R, Tardieux I. Host cell entry by apicomplexa parasites requires actin polymerization in the host cell. Cell Host Microbe. 2009 Mar 19;5(3):259-72.

Mayer DC, Cofie J, Jiang L, Hartl DL, Tracy E, Kabat J, Mendoza LH, Miller LH. Glycophorin B is the erythrocyte receptor of Plasmodium falciparum erythrocyte-binding ligand, EBL-1. Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5348-52.

Perez-Toledo K, Rojas-Meza AP, Mancio-Silva L, Hernandez-Cuevas NA, Delgadillo DM, Vargas M, Martinez-Calvillo S, Scherf A, Hernandez-Rivas R. Plasmodium falciparum heterochromatin protein 1 binds to tri-methylated histone 3 lysine 9 and is linked to mutually exclusive expression of var genes. Nucleic Acids Res. 2009 Mar 6. [Epub]

Agop-Nersesian C, Naissant B, Ben Rached F, Rauch M, Kretzschmar A, Thiberge S, Menard R, Ferguson DJ, Meissner M, Langsley G. Rab11A-controlled assembly of the inner membrane complex is required for completion of apicomplexan cytokinesis. PLoS Pathog. 2009 Jan;5(1):e1000270.

Rank G, Sutton R, Marshall V, Lundie RJ, Caddy J, Romeo T, Fernandez K, McCormack MP, Cooke BM, Foote SJ, Crabb BS, Curtis DJ, Hilton DJ, Kile BT, Jane SM. Novel roles for erythroid Ankyrin-1 revealed through an ENU-induced null mouse mutant. Blood. 2009 Jan 28. [Epub ahead of print]

McGowan S, Porter CJ, Lowther J, Stack CM, Golding SJ, Skinner-Adams TS, Trenholme KR, Teuscher F, Donnelly SM, Grembecka J, Mucha A, Kafarski P, Degori R, Buckle AM, Gardiner DL, Whisstock JC, Dalton JP. Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase. Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2537-42.

McMorran BJ, Marshall VM, de Graaf C, Drysdale KE, Shabbar M, Smyth GK, Corbin JE, Alexander WS, Foote SJ. Platelets kill intraerythrocytic malarial parasites and mediate survival to infection. Science. 2009 Feb 6;323(5915):797-800.

Qiu W, Wernimont A, Tang K, Taylor S, Lunin V, Schapira M, Fentress S, Hui R, Sibley LD. Novel structural and regulatory features of rhoptry secretory kinases in Toxoplasma gondii. EMBO J. 2009 Feb 5. [Epub ahead of print]

Putrianti ED, Silvie O, Kordes M, Borrmann S, Matuschewski K. Vaccine-Like Immunity against Malaria by Repeated Causal-Prophylactic Treatment of Liver-Stage Plasmodium Parasites. J Infect Dis. 2009 Feb 9. [Epub ahead of print]

Maier AG, Baum J, Smith B, Conway DJ, Cowman AF. Polymorphisms in the erythrocyte binding antigens-140 and 181 affect function and binding but not receptor specificity in Plasmodium falciparum. Infect Immun. 2009 Feb 9. [Epub ahead of print]

Lal K, Prieto JH, Bromley E, Sanderson SJ, Yates JR 3rd, Wastling JM, Tomley FM, Sinden RE. Characterisation of Plasmodium invasive organelles; an ookinete microneme proteome. Proteomics. 2009 Feb 10;9(5):1142-1151.

Sisowath C, Petersen I, Veiga MI, Martensson A, Premji Z, Bjorkman A, Fidock DA, Gil JP. In Vivo Selection of Plasmodium falciparum Parasites Carrying the Chloroquine-Susceptible pfcrt K76 Allele after Treatment with Artemether-Lumefantrine in Africa. J Infect Dis. 2009 Mar 1;199(5):750-757.

Koussis K, Withers-Martinez C, Yeoh S, Child M, Hackett F, Knuepfer E, Juliano L, Woehlbier U, Bujard H, Blackman MJ. A multifunctional serine protease primes the malaria parasite for red blood cell invasion. EMBO J. 2009 Feb 12. [Epub ahead of print]

Kumar KA, Baxter P, Tarun AS, Kappe SH, Nussenzweig V. Conserved protective mechanisms in radiation and genetically attenuated uis3(-) and uis4(-) plasmodium sporozoites. PLoS ONE. 2009;4(2):e4480.

Dharia NV, Sidhu AB, Cassera MB, Westenberger SJ, Bopp SE, Eastman RT, Plouffe D, Batalov S, Park DJ, Volkman SK, Wirth DF, Zhou Y, Fidock DA, Winzeler EA. Use of high-density tiling microarrays to globally identify mutations and elucidate mechanisms of drug resistance in Plasmodium falciparum. Genome Biol. 2009 Feb 13;10(2):R21.

Lopez-Rubio JJ, Mancio-Silva L, Scherf A. Genome-wide analysis of heterochromatin associates clonally variant gene regulation with perinuclear repressive centers in malaria parasites. Cell Host Microbe. 2009 Feb 19;5(2):179-90.

Olszewski KL, Morrisey JM, Wilinski D, Burns JM, Vaidya AB, Rabinowitz JD, Llinas M. Host-parasite interactions revealed by Plasmodium falciparum metabolomics. Cell Host Microbe. 2009 Feb 19;5(2):191-9.

Fox BA, Ristuccia JG, Gigley JP, Bzik DJ. Efficient gene replacements in Toxoplasma gondii strains deficient for nonhomologous end-joining. Eukaryot Cell. 2009 Feb 13. [Epub ahead of print]

Agbor-Enoh S, Seudieu C, Davidson E, Dritschilo A, Jung M. A novel inhibitor of Plasmodium histone deacetylase that cures P. berghei-infected mice. Antimicrob Agents Chemother. 2009 Feb 17. [Epub ahead of print]

Niang M, Yan Yam X, Preiser PR. The Plasmodium falciparum STEVOR multigene family mediates antigenic variation of the infected erythrocyte. PLoS Pathog. 2009 Feb;5(2):e1000307.

Carrara VI, Zwang J, Ashley EA, Price RN, Stepniewska K, Barends M, Brockman A, Anderson T, McGready R, Phaiphun L, Proux S, van Vugt M, Hutagalung R, Lwin KM, Phyo AP, Preechapornkul P, Imwong M, Pukrittayakamee S, Singhasivanon P, White NJ, Nosten F. Changes in the treatment responses to artesunate-mefloquine on the northwestern border of Thailand during 13 years of continuous deployment. PLoS ONE. 2009;4(2):e4551.

Russo I, Oksman A, Goldberg DE. Fatty acid acylation regulates trafficking of the unusual P. falciparum calpain to the nucleolus. Mol Microbiol. 2009 Feb 23. [Epub ahead of print]

Besteiro S, Michelin A, Poncet J, Dubremetz JF, Lebrun M. Export of a Toxoplasma gondii Rhoptry Neck Protein Complex at the Host Cell Membrane to Form the Moving Junction during Invasion. PLoS Pathog. 2009 Feb;5(2):e1000309.

Collins CR, Withers-Martinez C, Hackett F, Blackman MJ. An Inhibitory Antibody Blocks Interactions between Components of the Malarial Invasion Machinery. PLoS Pathog. 2009 Jan;5(1):e1000273. Epub 2009 Jan 23.

Goldszmid RS, Coppens I, Lev A, Caspar P, Mellman I, Sher A. Host ER-parasitophorous vacuole interaction provides a route of entry for antigen cross-presentation in Toxoplasma gondii-infected dendritic cells. J Exp Med. 2009 Jan 19. [Epub ahead of print]

Ghosh AK, Devenport M, Jethwaney D, Kalume DE, Pandey A, Anderson VE, Sultan AA, Kumar N, Jacobs-Lorena M. Malaria parasite invasion of the mosquito salivary gland requires interaction between the plasmodium TRAP and the anopheles saglin proteins. PLoS Pathog. 2009 Jan;5(1):e1000265. Epub 2009 Jan 16.

Srinivasan P, Coppens I, Jacobs-Lorena M. Distinct roles of Plasmodium rhomboid 1 in parasite development and malaria pathogenesis. PLoS Pathog. 2009 Jan;5(1):e1000262. Epub 2009 Jan 16.

Straub KW, Cheng SJ, Sohn CS, Bradley PJ. Novel components of the Apicomplexan moving junction reveal conserved and coccidia-restricted elements. Cell Microbiol. 2008 Dec 30. [Epub ahead of print]

Bejon P, Lusingu J, Olotu A, Leach A, Lievens M, Vekemans J, Mshamu S, Lang T, Gould J, Dubois MC, Demoitie MA, Stallaert JF, Vansadia P, Carter T, Njuguna P, Awuondo KO, Malabeja A, Abdul O, Gesase S, Mturi N, Drakeley CJ, Savarese B, Villafana T, Ballou WR, Cohen J, Riley EM, Lemnge MM, Marsh K, von Seidlein L. Efficacy of RTS,S/AS01E vaccine against malaria in children 5 to 17 months of age. N Engl J Med. 2008 Dec 11;359(24):2521-32. Epub 2008 Dec 8. Collins WE, Barnwell JW. A hopeful beginning for malaria vaccines. N Engl J Med. 2008 Dec 11;359(24):2599-601. Epub 2008 Dec 8. No abstract available.

Noedl H, Se Y, Schaecher K, Smith BL, Socheat D, Fukuda MM; Artemisinin Resistance in Cambodia 1 (ARC1) Study Consortium. Evidence of artemisinin-resistant malaria in western Cambodia. N Engl J Med. 2008 Dec 11;359(24):2619-20. Epub 2008 Dec 8. (this is worth to read, but not for journal club)

Yu M, Kumar TR, Nkrumah LJ, Coppi A, Retzlaff S, Li CD, Kelly BJ, Moura PA, Lakshmanan V, Freundlich JS, Valderramos JC, Vilcheze C, Siedner M, Tsai JH, Falkard B, Sidhu AB, Purcell LA, Gratraud P, Kremer L, Waters AP, Schiehser G, Jacobus DP, Janse CJ, Ager A, Jacobs WR Jr, Sacchettini JC, Heussler V, Sinnis P, Fidock DA. The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites. Cell Host Microbe. 2008 Dec 11;4(6):567-78. Spalding MD, Prigge ST. Malaria pulls a FASt one. Cell Host Microbe. 2008 Dec 11;4(6):509-11.

Epp C, Li F, Howitt CA, Chookajorn T, Deitsch KW. Chromatin associated sense and antisense noncoding RNAs are transcribed from the var gene family of virulence genes of the malaria parasite Plasmodium falciparum. RNA. 2009 Jan;15(1):116-27.

Gehde N, Hinrichs C, Montilla I, Charpian S, Lingelbach K, Przyborski JM. Protein unfolding is an essential requirement for transport across the parasitophorous vacuolar membrane of Plasmodium falciparum. Mol Microbiol. 2008 Nov 24. [Epub]

Boddey JA, Moritz RL, Simpson RJ, Cowman AF. Role of the Plasmodium Export Element in trafficking parasite proteins to the infected erythrocyte. Traffic. 2008 Dec 4. [Epub]

Handayani S, Chiu DT, Tjitra E, Kuo JS, Lampah D, Kenangalem E, Renia L, Snounou G, Price RN, Anstey NM, Russell B. High Deformability of Plasmodium vivax-Infected Red Blood Cells under Microfluidic Conditions. J Infect Dis. 2008 Dec 17. [Epub]

Foth BJ, Zhang N, Mok S, Preiser PR, Bozdech Z. Quantitative protein expression profiling reveals extensive post-transcriptional regulation and post-translational modifications in schizont-stage malaria parasites. Genome Biol. 2008 Dec 17;9(12):R177. [Epub]

Brick K, Watanabe J, Pizzi E. Core promoters are predicted by their distinct physicochemical properties in the genome of Plasmodium falciparum. Genome Biol. 2008 Dec 18;9(12):R178. [Epub]

Kafsack BF, Pena JD, Coppens I, Ravindran S, Boothroyd JC, Carruthers VB. Rapid Membrane Disruption by a Perforin-Like Protein Facilitates Parasite Exit from Host Cells. Science. 2008 Dec 18. [Epub]

Ganesan K, Ponmee N, Jiang L, Fowble JW, White J, Kamchonwongpaisan S, Yuthavong Y, Wilairat P, Rathod PK. A Genetically Hard-Wired Metabolic Transcriptome in Plasmodium falciparum Fails to Mount Protective Responses to Lethal Antifolates. PLoS Pathog. 2008 Nov;4(11):e1000214.

Teng R, Junankar PR, Bubb WA, Rae C, Mercier P, Kirk K. Metabolite profiling of the intraerythrocytic malaria parasite Plasmodium falciparum by (1)H NMR spectroscopy. NMR Biomed. 2008 Nov 19. [Epub]

Stoller P, Marti D, Schmuckli-Maurer J, Dobbelaere D, Frenz M. Multiphoton imaging of ultrashort pulse laser ablation in the intracellular parasite Theileria. J Biomed Opt. 2008 July/August;13(4):044021

Sautel CF, Ortet P, Saksouk N, Kieffer S, Garin J, Bastien O, Hakimi MA. The histone methylase KMTox interacts with the redox-sensor peroxiredoxin-1 and targets genes involved in Toxoplasma gondii antioxidant defences. Mol Microbiol. 2008 Nov 5. [Epub ]

Glushakova S, Mazar J, Hohmann-Marriott MF, Hama E, Zimmerberg J. Irreversible effect of cysteine protease inhibitors on the release of malaria parasites from infected erythrocytes. Cell Microbiol. 2008 Oct 22. [Epub]

Steinbuechel M, Matuschewski K. Role for the Plasmodium sporozoite-specific transmembrane protein S6 in parasite motility and efficient malaria transmission. Cell Microbiol. 2008 Oct 30. [Epub ]

Okamoto N, Spurck TP, Goodman CD, McFadden GI. The apicoplast and mitochondrion in gametocytogenesis of Plasmodium falciparum. Eukaryot Cell. 2008 Nov 7. [Epub]

Zhao Z, Fux B, Goodwin M, Dunay IR, Strong D, Miller BC, Cadwell K, Delgado MA, Ponpuak M, Green KG, Schmidt RE, Mizushima N, Deretic V, Sibley LD, Virgin HW. Autophagosome-independent essential function for the autophagy protein Atg5 in cellular immunity to intracellular pathogens. Cell Host Microbe. 2008 Nov 13;4(5):458-69. + Whitmarsh RJ, Hunter CA. Digest this! A role for autophagy in controlling pathogens. Cell Host Microbe. 2008 Nov 13;4(5):413-4.

Baum J, Chen L, Healer J, Lopaticki S, Boyle M, Triglia T, Ehlgen F, Ralph SA, Beeson JG, Cowman AF. Reticulocyte-binding protein homologue 5 - An essential adhesin involved in invasion of human erythrocytes by Plasmodium falciparum. Int J Parasitol. 2008 Oct 25. [Epub ] + Rodriguez M, Lustigman S, Montero E, Oksov Y, Lobo CA. PfRH5: a novel reticulocyte-binding family homolog of plasmodium falciparum that binds to the erythrocyte, and an investigation of its receptor. PLoS ONE. 2008 Oct 1;3(10):e3300.

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Daher W, Oria G, Fauquenoy S, Cailliau K, Browaeys E, Tomavo S, Khalife J. A Toxoplasma gondii Leucine Rich Repeat Protein binds Phosphatase type 1 protein and negatively regulates its activity. Eukaryot Cell. 2007 Jul 27; [Epub]

Kyes SA, Kraemer SM, Smith JD. Antigenic Variation in Plasmodium falciparum: Gene Organization and Regulation of the var Multigene Family. Eukaryot Cell. 2007 Jul 20; [Epub]

Frankland S, Elliott SR, Yosaatmadja F, Beeson JG, Rogerson SJ, Adisa A, Tilley L. Serum lipoproteins promote efficient presentation of the malaria virulence protein, PfEMP1, at the erythrocyte surface. Eukaryot Cell. 2007 Jul 20; [Epub]

Dorin-Semblat D, Quashie N, Halbert J, Sicard A, Doerig C, Peat E, Ranford-Cartwright L, Doerig C. Functional characterization of both MAP kinases of the human malaria parasite Plasmodium falciparum by reverse genetics. Mol Microbiol. 2007 Jul 26; [Epub]

Villard V, Agak GW, Frank G, Jafarshad A, Servis C, Nebie I, Sirima SB, Felger I, Arevalo-Herrera M, Herrera S, Heitz F, Backer V, Druilhe P, Kajava AV, Corradin G. Rapid Identification of Malaria Vaccine Candidates Based on alpha-Helical Coiled Coil Protein Motif. PLoS ONE. 2007 Jul 25;2:e645.

Khan A, Fux B, Su C, Dubey JP, Darde ML, Ajioka JW, Rosenthal BM, Sibley LD. Recent transcontinental sweep of Toxoplasma gondii driven by a single monomorphic chromosome. Proc Natl Acad Sci U S A. 2007 Sep 5; [Epub]

Antia M, Herricks T, Rathod PK. Microfluidic Modeling of Cell-Cell Interactions in Malaria Pathogenesis. PLoS Pathog. 2007 Jul 20;3(7):e99 [Epub]

Tarun AS, Dumpit RF, Camargo N, Labaied M, Liu P, Takagi A, Wang R, Kappe SH. Protracted Sterile Protection with Plasmodium yoelii Pre-erythrocytic Genetically Attenuated Parasite Malaria Vaccines Is Independent of Significant Liver-Stage Persistence and Is Mediated by CD8+ T Cells. J Infect Dis. 2007 Aug 15;196(4):608-16.   + Jobe O, Lumsden J, Mueller AK, Williams J, Silva-Rivera H, Kappe SH, Schwenk RJ, Matuschewski K, Krzych U. Genetically Attenuated Plasmodium berghei Liver Stages Induce Sterile Protracted Protection that Is Mediated by Major Histocompatibility Complex Class I-Dependent Interferon- gamma -Producing CD8+ T Cells.  J Infect Dis. 2007 Aug 15;196(4):599-607

Montgomery J, Mphande FA, Berriman M, Pain A, Rogerson SJ, Taylor TE, Molyneux ME, Craig A.  Differential var gene expression in the organs of patients dying of falciparum malaria. Mol Microbiol. 2007 Jun 6; [Epub]

Usynin I, Klotz C, Frevert U. Malaria circumsporozoite protein inhibits the respiratory burst in Kupffer cells. Cell Microbiol. 2007 Jun 15; [Epub]

Jenkins N, Wu Y, Chakravorty S, Kai O, Marsh K, Craig A. Plasmodium falciparum Intercellular Adhesion Molecule-1-Based Cytoadherence-Related Signaling in Human Endothelial Cells. J Infect Dis. 2007 Jul 15;196(2):321-327.

Subramanian S, Sijwali PS, Rosenthal PJ. Falcipain cysteine proteases require bipartite motifs for trafficking to the plasmodium falciparum food vacuole. J Biol Chem. 2007 Jun 12; [Epub]

Sazawal S, Black RE, Ramsan M, Chwaya HM, Dutta A, Dhingra U, Stoltzfus RJ, Othman MK, Kabole FM.  Effect of zinc supplementation on mortality in children aged 1-48 months: a community-based randomised placebo-controlled trial. Lancet. 2007 Mar 17;369(9565):927-34.   + Questions Muller O, Garenne M, Becher H, Sie A, Kouyate B., Verhoef H.  and reply Black RE, Sazawal S, Dhingra U, Dutta A.  Lancet. 2007 Jun 30;369(9580):2155-7.

Cyrklaff M, Kudryashev M, Leis A, Leonard K, Baumeister W, Menard R, Meissner M, Frischknecht F. Cryoelectron tomography reveals periodic material at the inner side of subpellicular microtubules in apicomplexan parasites. J Exp Med. 2007 Jun 11;204(6):1281-7.

Beeson JG, Andrews KT, Boyle M, Duffy MF, Choong EK, Byrne TJ, Chesson JM, Lawson AM, Chai W. Structural basis for binding of Plasmodium falciparum erythrocyte membrane protein 1 to chondroitin sulfate and placental tissue and the influence of protein polymorphisms on binding specificity. J Biol Chem. 2007 Jun 11; [Epub]

Chene A, Donati D, Guerreiro-Cacais AO, Levitsky V, Chen Q, Falk KI, Orem J, Kironde F, Wahlgren M, Bejarano MT. A Molecular Link between Malaria and Epstein-Barr Virus Reactivation. PLoS Pathog. 2007 Jun 8;3(6):e80 [Epub]

Gissot M, Kelly KA, Ajioka JW, Greally JM, Kim K. Epigenomic Modifications Predict Active Promoters and Gene Structure in Toxoplasma gondii. PLoS Pathog. 2007 Jun 8;3(6):e77 [Epub]

Saxena AK, Wu Y, Garboczi DN. Plasmodium P25 and P28 surface proteins: potential transmission-blocking vaccines. Eukaryot Cell. 2007 Jun 8; [Epub]

Lavazec C, Sanyal S, Templeton TJ. Expression switching in the stevor and Pfmc-2TM superfamilies in Plasmodium falciparum. Mol Microbiol. 2007 Jun;64(6):1621-34.

Parsons M, Karnataki A, Feagin JE, Derocher A. Protein trafficking to the apicoplast: deciphering the apicomplexan solution to secondary endosymbiosis.  Eukaryot Cell. 2007 May 18; [Epub]

Mueller AK, Deckert M, Heiss K, Goetz K, Matuschewski K, Schluter D. Genetically Attenuated Plasmodium berghei Liver Stages Persist and Elicit Sterile Protection Primarily via CD8 T Cells. Am J Pathol.2007 May 18; [Epub]

Painter HJ, Morrisey JM, Mather MW, Vaidya AB. Specific role of mitochondrial electron transport in blood-stage Plasmodium falciparum. Nature. 2007 Mar 1;446(7131):88-91.

Nguyen HD, Yoshihama M, Kenmochi N. The Evolution of Spliceosomal Introns in Alveolates. Mol Biol Evol. 2007 Mar 1; [Epub]

Promeneur D, Liu Y, Maciel J, Agre P, King LS, Kumar N..  Aquaglyceroporin PbAQP during intraerythrocytic development of the malaria parasite Plasmodium berghei. Proc Natl Acad Sci U S A. 2007 Feb 6; [Epub]

Kyes S, Christodoulou Z, Pinches R, Kriek N, Horrocks P, Newbold C.  Plasmodium falciparum var gene expression is developmentally controlled at the level of RNA polymerase II-mediated transcription initiation.  Mol Microbiol. 2007 Jan 22; [Epub]

Chookajorn T, Dzikowski R, Frank M, Li F, Jiwani AZ, Hartl DL, Deitsch KW. Epigenetic memory at malaria virulence genes. Proc Natl Acad Sci U S A. 2007 Jan 5; [Epub]

Joergensen L, Vestergaard LS, Turner L, Magistrado P, Lusingu JP, Lemnge M, Theander TG, Jensen AT. 3D7-Derived Plasmodium falciparum Erythrocyte Membrane Protein 1 Is a Frequent Target of Naturally Acquired Antibodies Recognizing Protein Domains in a Particular Pattern Independent of Malaria Transmission Intensity. J Immunol. 2007 Jan 1;178(1):428-35.

Parroche P, Lauw FN, Goutagny N, Latz E, Monks BG, Visintin A, Halmen KA, Lamphier M, Olivier M, Bartholomeu DC, Gazzinelli RT, Golenbock DT.  Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9. Proc Natl Acad Sci U S A. 2007 Jan 29; [Epub]

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