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Department of Pediatric Infectious Diseases

Department of Pediatric Infectious Diseases

The Department of Pediatric Infectious Diseases is a recently expanded department under the Clinical Research Division at Institute of Tropical Medicine. We work on a wide range of infectious diseases with special attention on severe pediatric infectious diseases including pneumonia, diarrhea, dengue and malaria. Our research interests include integration of clinical, environmental and social issues at international, national and local levels.

Members

  • Professor Masahiro Hashizume
  • Professor Laymyint Yoshida
  • Assistant Professor Chris Fook Sheng Ng
  • Assistant Professor Yoonhee Kim
  • Assistant Professor Michiko Toizumi
  • Assistant Professor Noriko Kitamura
  • Assistant Professor Chihiro Iwasaki
  • Assistant Professor Mizuki Takegata
  • Assistant Professor Le Nhat Minh
  • Assistant Setsuko Hirakura
  • Assistant Nozomi Oka
  • Assistant Kaori Yoshida
  • Graduate student Keisuke Yoshihara
  • Graduate student Eriko Ikeda
  • Graduate student Naohiko Matsushita
  • Graduate student Saki Tanaka
  • Graduate student Atsushi Fujioka
  • Visiting Researcher Chisato Imai

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Activities

Pediatric Respiratory Infections

Cohort studies on Pediatric Infectious Diseases in Vietnam

We receive funding from the Japan Initiative for Global Research Network on Infectious Diseases (JGRID), Japan Agency for Medical Research and Development (AMED) to conduct a large population based cohort study on Pediatric Infectious Diseases in Nha Trang, central Vietnam since 2006. We are focusing on severe common pediatric infectious diseases (SPID) such as acute respiratory infection (ARI), diarrhea and dengue which are the major causes of under 5 mortality.
Pediatric ARI surveillance: A population based hospitalized Pediatric ARI surveillance at Khanh Hoa General Hospital, Nha-Trang, Vietnam was established to determine incidence, etiology and risk factors for pediatric ARI/pneumonia since 2007. We also investigate the emergence of new viruses and its molecular and clinical importance.
Birth cohort study: We are also conducting a birth cohort study on 2000 new born babies in Nha Trang, Vietnam since 2009. This study was conducted to study congenital infection and host genetic factors on physical-neurological development of the child and development of SPID. We are also studying congenital rubella infection and its complication in Vietnam.
Pneumococcal conjugate vaccine (PCV) reduced dosing trial: We received a multimillion dollar grant from Bill and Melinda Gates Foundation to conduct a PCV reduce dosing trial in Vietnam. We believe that the study outcome will change global PCV vaccination strategy to improve the availability of PCV and other vaccines in developing countries.

Health impacts of global environmental change

Our research interests extend over a range of issues in environmental epidemiology. The current research topics, which we work in collaboration with both the international and Japanese colleagues, focus on the health impacts of atmospheric environmental changes including global climate change and transboundary and local air pollution. Ongoing projects include:

  1. Effects of flooding and weather on diarrhoea, acute respiratory infections and other infectious diseases.
  2. Ocean-atmosphere interaction phenomena including the Indian Ocean Dipole and its association with malaria and cholera in the Eastern and Southern Africa.
  3. Health effects of local and transboundary air pollution in Japan and in the East and Southeast Asia.
  4. Mortality risk of temperature extremes in tropical climate where we estimate excess mortality associated with exposure to temperature extremes and the extended period of heat in tropical countries.
  5. Respiratory health effects of the different chemical composition of airborne particulate matter and the sources.
  6. Heat effect on mortality in Japan.
  7. Associations between weather factors and suicide in multiple countries in Asia, Europe, and America.

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