Department of Immunogenetics
This department is focusing on the pathogenic genetic factors of the host and the parasite in the most important tropical infectious diseases by using immunology and genetics.
Research activities:
To clarify the molecular mechanisms in the protective and/ or pathogenic host response to human pathogens such as Dengue Virus, Malaria, Trypanosoma cruzi and Schistosoma, the following research projects are going on in our laboratory.
Members
- Professor Kenji Hirayama
- Associate Professor Nobu Ohwatari
- Senior Assistant Professor(Project) Mihoko Kikuchi
- Assistant Professor Nguyen Huy Tien
- Assistant Professor Shuaibu Mohammed Nasir
- Assistant Junko Hayashima
- Assistant Syuji Miyazaki
- COE Technician Kuniko Shimoda
- Graduate Student Tran Thi Ngoc Ha
- Graduate Student Del Puerto rodas Ramona Florencia
- Graduate Student Daniel Boamah
- Graduate Student(COE researcher) Cherif Mahamoud Sama
- Graduate Student(COE researcher) Lam Quoc Bao
- Graduate Student Omar Ahamed Din Hassan
- Graduate Student Mbanefo Evaristus Chibunna
- Graduate Student Yukimi Katagami
- Graduate Student Dang My Nhi
To the Site of our department»
Activities
Malaria
- Genetic susceptibility to severe forms of malaria (cerebral malaria, severe anemia) is analyzed by case-control study in South East Asia, South Pacific and West Africa.
Schistosomiasis
- Immunological regulation of the pathogenic anti egg response in the resistant and susceptible persons, to post-schistosomal liver fibrosis in China and Philippines.
Chagas disease
- Genetic susceptibility to different clinical types of chronia Chagas disease, namely, indeterminate, cardiac, and digestive forms, is analyzed by case control study in Bolivia where Chagas disease is still highly endemic.
- Host and Parasite factors influencing on the reactivity to the chemotherapy in the paediatric patients with chronic Chagas Disease.
- Genetic analysis of Trypanosomes in Latin Americas by using local isolates and molecular biology.
Dengu fever:Pasteurlnstitute HCMC(Vietnam)
- Pathogenesis of the DHF (Dengue Hemorragic Fever)
Host factors will be detected by the Popula-tional genetic analysis of the patients with DHF and non DHF.
Collaborations:
The research here is performed based on the well arranged collaborative projects with the following facilities.
１．Malaria: Thammasat University (Thailand), Noguchi Memorial Medical Research Institute (Ghana), Karolinska Institute (Sweden), Kenya Medical Research Institute (KEMRI).
２．Schistosmiasis: Jiangxi Provincial Institute of Parasitic Diseases (China), Jiangsu Provincial Institute of Parasitic Disease (China), Univ. Philippines and RITM (Philippines).
３．Chagas Disease: Center of Tropical Medicine, Sirani Clinic, and Hospital Japones (Bolivia), IICS University of Asuncion (Paraguay).
