Hitoshi Kawada

E-Mail: vergiss[at]nagasaki-u.ac.jp

Associate Professor

Field:

Position:

Research:

Achievements:

Japan, Southeast Asia, Africa
Ecology, behavior, control method, and insecticide resistance of vector mosquitoes

1. Kawada, H., C. Kitamura (1983): The reproductive behavior of the brown marmorated stink bug, Halyomorpha mista Uhler (Heteroptera: Pentatomidae) I. Observation of mating behavior and multiple copulation. Appl. Ent. Zool. 18: 234-242. PDF

2. Kawada, H. and C. Kitamura (1983): Bionomics of the brown marmorated stink bug, Halyomorpha mista. Jap. J. appl. Ent. Zool. 27: 304-306. PDF

3. Hatakoshi, M., H. Kawada, S. Nishida, H. Kishida and I. Nakayama (1987): Laboratory evaluation of 2-[1-methyl-2- (4-phenoxy-phenoxy) ethoxy] pyridine against larvae of  mosquitoes and housefly. Jpn. J. Sanit. Zool. 38: 271-274. PDF

4. Kawada, H., K. Dohara, G. Shinjo (1987): Evaluation of larvicidal potency of insect growth regulator, 2-[1-methyl-2-(4-phenoxy-phenoxy) ethoxy] pyridine, against the housefly, Musca domestica. Jpn. J. Sanit. Zool. 38: 317-322. PDF

5. Tsuda, S., T. Ohtsubo, H. Kawada, Y. Manabe, N. Kishibuchi, G. Shinjo and K. Tsuji (1987): A way of action of the fenitrothion microcapsule as a residual cockroach control formulation. J. Pestic. Sci. 12: 23-27. PDF

6. Ohtsubo, T., S. Tsuda, H. Kawada, Y. Manabe, N. Kishibuchi, G. Shinjo and K. Tsuji (1987): Formulation factors of the fenitrothion microcapsule influencing the residual efficacy against the german cockroach. J. Pestic. Sci. 12: 43-47. PDF

7. Kawada, H., K. Dohara, G. Shinjo (1987): Laboratory and field evaluation of an insect growth regulator, 4-phenoxyphenyl (RS)-2-(2-pyridyloxy) propyl ether, as a mosquito larvicide. Jpn. J. Sanit. Zool. 39: 339-346. PDF

8. Kawada, H., I. Kojima, G. Shinjo (1989): Laboratory evaluation of a new insect growth regulator pyriproxyfen, as a cockroach control agent. Jpn. J. Sanit. Zool. 40: 195-201. PDF

9. Suzuki, H., T. Okazawa, N. Kere and H. Kawada (1989): Field evaluation of a new insect growth regulator, pyriproxyfen, against Anopheles farauti, the main vector of malaria in the Solomon Islands. Jpn. J. Sanit. Zool., 40: 253-257. PDF

10. Kawada, H., M. Makita, S. Tsuda, T. Ohtsubo, G. Shinjo, K. Tsuji (1990): Efficacy and the way of action of fenitrothion microcapsules for cockroach control. Jpn. J. Environ. Entomol. Zool. 2: 6-13. PDF

11. Okazawa, T., B. Bakote'e, H. Suzuki, H. Kawada and N. Kere (1991): Field evaluation of an insect growth regulator, pyriproxyfen, against Anopheles punctulatus on north Guadalcanal, Solomon Islands. J. Am. Mosq. Control Assoc.7: 604-607. PDF

12. Kawada, H., S. Senbo, Y. Abe (1992): Effects of pyriproxyfen on the reproduction of the housefly, Musca domestica, and the German cockroach, Blattella germanica. Jpn. J. Sanit. Zool. 43: 169-175. PDF

13. Kawada, H., C. Kitamura (1992): The Tachinid fly, Bogosia sp. (Diptera: Tachinidae), as a parasitoid of the brown marmorated stink bug, Halyomorpha mista UHLER (Heteroptera: Pentatomidae). Jpn. J. Environ. Entomol. Zool. 4: 65-70. PDF

14. Senbo, S., S. Aki, H. Kawada, T. Itoh and Y. Abe (1992): The influence of smoke density on knockdown efficacy of mosquito coil against adults of Culex pipiens pallens. Jpn. J. Sanit. Zool. 43: 71-76. PDF

15. Kawada, H., T. Ohtsubo, S. Tsuda, Y. Abe, K. Tsuji (1993): Insecticidal characteristics of cyphenothrin microcapsule for cockroach control. Jpn. J. Environ. Entomol. Zool. 5: 65-72. PDF

16. Kawada, H., Y. Shono, T. Itoh, Y. Abe (1993): Laboratory evaluation of and insect growth regulators against several species of Anopheline mosquitoes. Jpn. J. Sanit. Zool. 44: 349-353. PDF

17. Kawada, H., M. Ogawa, T. Itoh, Y. Abe, K. Tsuji (1994): Laboratory evaluation of fenitrothion microcapsules as a new residual spraying formulation for mosquito control. J. Am. Mosq. Control Assoc. 10: 385-389. PDF

18. Itoh, T., H. Kawada , Y. Abe, Y. Eshita, Y. Rongsriyam and A. Igarashi (1994): Utilization of blood-fed females of Aedes aegypti as a   vehicle for the transfer of the insect growth regulator pyriproxyfen to larval habitats. J. Am. Mosq. Control Assoc. 10: 344-347. PDF

19. Kawada, H., T. Kohama and Y. Abe (1994): Larvicidal activity of a water-soluble granular formulation of the insect growth regulator, pyriproxyfen, against Culex mosquitoes. Jpn. J. Envitron. Entomol. Zool. 6: 68-77. PDF

20. Kawada, H., M. Ogawa, T. Itoh, Y. Abe (1995): Biological and physicochemical properties of fenitrothion microcapsules as a residual spraying formulation for mosquito control. J. Am. Mosq. Control Assoc. 11: 441-447. PDF

21. Kawada, H. (1995): Studies on the modes of action of microencapsulated insecticides. Jpn. J. Environ. Zool. Entomol. 7:37-48. PDF

22. Kawada, H., M. Hirano (1996): Insecticidal effects of an insect growth regulator, pyriproxyfen on the cat flea, Ctenocephalides felis (Bouche) as a residual spraying formulation. J. Med. Entomol. 33: 819-822. PDF

23. Hatakoshi, S., H. Kishida, H. Kawada, H. Ouchi, N. Isobe and T. Hagino (1997): Pyriproxyfen a new insect growth regulator. Sumitomokagaku 1997-I: 4-20. PDF

24. Hirano, M., M. Hatakoshi, H. Kawada, Y. Takimoto (1998): Pyriproxyfen and other juvenile hormone analogues. Rev. Toxicol. 2: 357-394. PDF

25. Satho, T., Y. Tsuda, P. Somboon, H. Kawada and M. Takagi (2003): Difference in the larval susceptibility to pyriproxyfen in nine colonies of six vector mosquito species. Med. Entomol. Zool. 54: 155-160. PDF

26. Kawada, H., Y. Maekawa, Y. Tsuda. M. Takagi (2004): Laboratory and field evaluation of spatial repellency with metofluthrin impregnated paper strip against mosquitoes in Lombok Island, Indonesia. J. Am. Mosq. Control Assoc. 20: 292-298. PDF

27. Kawada, H., Y. Maekawa, Y. Tsuda, M. Takagi (2004): Trial of spatial repellency of metofluthrin impregnated paper strip against Anopheles and Culex in shelters without walls in Lombok, Indonesia. J. Am. Mosq. Control Assoc. 20: 434-437. PDF

28. Kawada, H., Takagi (2004): Photoelectric sensing device for recording mosquito host-seeking behavior in the laboratory. J. Med. Entomol. 41: 873-881. PDF

29. Argueta, T. B. O., H. Kawada and M. Takagi (2004): Spatial repellency of metofluthrin-impregnated multilayer paper strip against Aedes albopictus in the outdoor conditions, Nagasaki, Japan. Med. Entomol. Zool. 55: 211-216. PDF

30. Argueta, T. B. O., H. Kawada, M. Sugano, S. Kubota, Y. Shono, K. Tsushima and M. Takagi (2004): Comparative insecticidal efficacy of a new pyrethroid, metofluthrin, against colonies of Asian Culex quinquefasciatus and Culex pipiens pallens. Med. Entomol. Zool. 55: 289-294. PDF

31. Kawada, H., Ng. T. Yen, Ng. T. Hoa, Tr. M. Sang, Ng. V. Dan, M. Takagi (2005): Field evaluation of spatial repellency of metofluthrin impregnated resin strips against mosquitoes in Hai Phong city, Vietnam. Am. J. Trop. Med. Hyg. 73:350-353. PDF

32. Kawada H., Y. Maekawa, M. Takagi (2005): Field trial of the spatial repellency of metofluthrin-impregnated plastic strip against mosquitoes in shelters without walls (Beruga) in Lombok, Indonesia. J. Vector Ecol. 30: 181-185.  PDF

33. Kawada, H., H. Tatsuta, K. Arikawa , M. Takagi (2005): Comparative study on the relationship between photoperiodic host-seeking behavioral patterns and the eye parameters of mosquitoes. J. Insect Physiol. 52: 67-75.  PDF

34. Wang, S.-Q., T. V. Phong, N. Tuno, H. Kawada and M.Takagi (2005): Sensitivity of the larvivorous copepod species, Mesocyclops pehpeiensis and Megacyclops viridis (Cyclopoida:Cyclopidae) to the insect growth regulator, pyriproxyfen. J. Am. Mosq. Control Assoc. 21: 483-488. PDF

35. Kawada, H., S. Takemura, K. Arikawa, M. Takagi (2005): Comparative study on nocturnal behavior of Aedes aegypti and Aedes albopictus. J. Med. Entomol. 42: 312-318. PDF

36. Kawada, H., S. Saita, K. Shimabukuro, M. Hirano, M. Koga, T. Iwashita, M. Takagi (2006): Effectiveness in controlling mosquitoes with EcoBio-Block® S - a novel integrated water purifying concrete block formulation combined with the insect growth regulator pyriproxyfen. J. Am. Mosq. Control Assoc. 22: 451-456. PDF

37. Kawada, H., T. Iwasaki, L. L. Loan, T. K. Tien, Ng. T. N. Mai, Y. Shono, Y. Katayama, M. Takagi (2006): Field evaluation of spatial repellency of metofluthrin-impregnated latticework plastic strips against Aedes aegypti (L.) and analysis of environmental factors affecting its efficacy in My Tho city, Tien Giang, Vietnam. Am. J. Trop. Med. Hyg. 75: 1153-1157. PDF

38. Temu, E. A., I. Kimani, N. Tuno, H. Kawada, J. N. Minjas, M. Takagi (2006): Monitoring chloroquine resistance using Plasmodium falciparum parasites isolated from wild mosquitoes in TanzaniaAm. J. Trop.Med. Hyg. 75: 1182-1187. PDF

39. Kawada, H., S. Honda, M. Takagi (2007): Comparative laboratory study on the reaction of Aedes aegypti and Aedes albopictus to different attractive cues in a mosquito trap. J. Med. Entomol. 44: 427-432. PDF

40. Temu, E. A., J. N. Minjas, N. Tuno, H. Kawada, M. Takagi (2007): Identification of four members of the Anopheles funestus (Diptera: Culicidae) group and their role in Plasmodium falciparum transmission in Bagamoyo coastal Tanzania. Acta Trop.102: 119-125. PDF

41. Sugiura, M., Y. Horibe, H. Kawada, M. Takagi (2008): Insect spiracle as the main penetration route of pyrethroids. Pestic. Biochem. Physiol. 91: 135-140. PDF

42. Kawada, H., E. A. Temu, J. N. Minjas, O. Matsumoto, T. Iwasaki, M. Takagi (2008): Field evaluation of spatial repellency of metofluthrin-impregnated latticework plastic strips against mosquitoes of Anopheles gambiae group in Bagamoyo, coastal Tanzania. J. Am. Mosq. Control Assoc. 24: 404-409. PDF

43. Phong, T. V., N. Tuno, H. Kawada, and M. Takagi (2008): Comparative evaluation of fecundity and survivorship of six copepod (Copepoda: Cyclpidae) species, in relation to selection of candidate biological control agents against Aedes aegypti. J. Am. Mosq. Control Assoc. 24: 61-69. PDF

44. Kawada, H., Y. Higa, T. Y. Nguyen, H. S. Tran, T. H. Nguyen, and M. Takagi (2009): Nationwide investigation on the pyrethroid susceptibility of mosquito larvae collected from used tires in Vietnam. PLoS Negl.Trop.Dis. 3: e391. PDF

45. Kawada, H., Y. Higa, O. Komagata, S. Kasai, T. Tomita, N. T. Yen, L. L. Loan, R. A. P. Sánchez and M. Takagi (2009): Widespread distribution of a newly found point mutation in voltage-gated sodium channel in pyrethroid-resistant Aedes aegypti populations in Vietnam. PLoS Negl.Trop.Dis. 3: e0000527. PDF

46. Tsuzuki, A., T. Huynh, T. Tsunoda, L. L. Luu, H. Kawada, and M. Takagi (2009): Effect of existing practices on reducing Aedes aegypti pre-adults in key breeding containers in Ho Chi Minh City, Vietnam. Am. J. Trop. Med. Hyg. 80: 752-757. PDF

47. Kawada, H. (2009) : An Inconvenient Truth of Pyrethroid - Does it have a promising future? -. In J Clark, J. R. Bloomquist, H. Kawada [ed.] Advances in Human Vector Control (ACS Symposium Book 1014) American Chemical Society, New York. PDF

48. Kawada, H. and M. Takagi (2009): Photoperiodic host-seeking behavioral pattern of mosquitoes of medical importance. In R. P. Maes [ed.] Insect Physiology: New Research. Nova Science Publishers. New York.

49. Kawada, H., Y. Maekawa, M. Abe, K. Ohashi, and M. Takagi (2010): Spatial distribution and pyrethroid susceptibility of mosquito larvae collected from catch basins in parks in Nagasaki city, Nagasaki, Japan. Jpn. J. Infect. Dis. 63: 19-24. PDF

50. Higa, Y., Y. T. Nguyen, H. Kawada, S. H. Tran, H. T. Nguyen and M. Takagi (2010): Geographic distribution of Aedes aegypti and Aedes albopictus collected from used tires in Vietnam. J. Am. Mosq. Control Assoc. 26: 1-9. PDF

51. Ohba S, H. Kawada, O.G. Dida, D. Juma, G. Sonye, N. Minakawa, M. Takagi (2010):  Predators of Anopheles gambiae s.l. (Diptera: Culicidae) larvae in wetlands, western Kenya: Confirmation by PCR method. J. Med. Entomol. 47: 783-787. PDF

52. Kawada, H., G. O. Dida, K. Ohashi, O. Komagata, S. Kasai, T. Tomita, G. Sonye, Y. Maekawa, C. Mwatele, S. M. Njenga, C. Mwandawiro, N. Minakawa, and M. Takagi (2011): Multimodal pyrethroid resistance in malaria vectors Anopheles gambiae s.s., Anopheles arabiensis, and Anopheles funestus s.s. in western Kenya. PLoS One 6: e22574. PDF

53. Kawada, H., K. Futami, O. Komagata, S. Kasai, T. Tomita, G. Sonye, C. Mwatele, S. M. Njenga, C. Mwandawiro, N. Minakawa, and M. Takagi (2011): Distribution of a knockdown resistance mutation (L1014S) in Anopheles gambiae s.s. and Anopheles arabiensis in Western and Southern Kenya. PLoS One 6: e24323. PDF

54. Sugiura, M, Y. Horibe, H. Kawada, and M. Takagi (2011): Effect of different droplet size on the knockdown efficacy of directly sprayed insecticides. Pest Manag. Sci. 67: 1115-1123. PDF

55. Ohba, S., T.T. T. Huynh, H. Kawada, L. L. Le, H. T. Ngoc, S. L. Hoang, Y. Higa, M. Takagi (2011): Heteropteran insects as mosquito predators in water jars in southern Vietnam. J. Vector Ecol. 36: 170-174. PDF

56. Tsuzuki, A., B. Khamlome, H. Kawada, H. Eto, S. Phompida and M Takagi (2011): The efficacy and physical condition of Olyset insecticide-treated nets after 5 years use in rural Lao PDR. Southeast Asian J. Trop. Med. Pub. Hlth 42: 268-273. PDF

57. Kawada, H (2012): New Mosquito Control Techniques as Countermeasures Against Insecticide Resistance. In F Perveen [ed.] Insecticides - Advances in Integrated Pest Management. InTech. PDF

58. Kawada, H., G. O. Dida, K. Ohashi, G. Sonye, S. M. Njenga, C. Mwandawiro, N. Minakawa, and M. Takagi (2012): Preliminary evaluation of the insecticide-impregnated ceiling nets with coarse mesh size as a barrier against the invasion of malaria vectors. Jpn. J. Infect. Dis. 65: 243-246. PDF

59. Kawada, H., G. O. Dida, G. Sonye, S. M. Njenga, C. Mwandawiro, N. Minakawa (2012): Reconsideration of Anopheles rivulorum as a Vector of Plasmodium falciparum in Western Kenya: some evidence from biting time, blood preference, sporozoite positive rate, and pyrethroid resistance. Parasit. Vect. 5: 230. PDF@

60. Tsunoda, T., H. Kawada, T.T.T. Huynh, L.L. Luu, S.H. Le, H.N. Tran, H.T.Q. Vu, H.M. Le, F. Hasebe, A. Tsuzuki and M. Takagi (2013): Field trial on a novel control method for the dengue vector, Aedes aegypti by the systematic use of Olyset® Net and pyriproxyfen in Southern Vietnam. Parasit. Vect. 6: 6. PDF

61. Itokawa, K., O. Komagata, S. Kasai, H. Kawada, C. Mwatele, G. O. Dida, S. M. Njenga, C. Mwandawiro and T. Tomita (2013): Global spread and genetic variants of the two CYP9M10 haplotype forms associated with insecticide resistance in Culex quinquefasciatus Say. Heredity 111:216-226. PDF

62. Ohba, S., K. Ohashi, E. Pujiyati, Y. Higa, H. Kawada, N. Mito and M. Takagi (2013): The Effect of pyriproxyfen as a gpopulation growth regulatorh against Aedes albopictus under semi-field conditions. PLoS One 8: e67045. PDF

63. Pujiyati, E., H. Kawada, T. Sunahara, S. Kasai and N. Minakawa (2013): Pyrethroid resistance status of Aedes albopictus (Skuse) collected in Nagasaki City, Japan. Jpn. J. Environ. Entomol. Zool. 24: 143-153. PDF

64. Kawada, H., K. Ohashi, G. O. Dida, G. Sonye, S. M. Njenga, C. Mwandawiro and N. Minakawa (2014): Insecticidal and repellent activities of pyrethroids to the three major pyrethroid-resistant malaria vectors in western Kenya. Parasit. Vect. 7:208. PDF

65. Kawada, H. (2014): Trials for the possible new controlling techniques as countermeasures against insecticide resistant vector mosquitoes. Med. Entomol. Zool. 65: 45-59. PDF

66. Kawada, H., S. Z. M. Oo, S. Thaung, E. Kawashima, Y. N. M. Maung, H. M. Thu, K. Z. Thant and N. Minakawa (2014): Co-occurrence of the point mutations in voltage-gated sodium channel in pyrethroid resistant Aedes aegypti populations in Myanmar. PLoS Neg. Trop. Dis. 8: e3032. PDF @

67. Kawada, H., K. Ohashi, G. O. Dida, G. Sonye, S. M. Njenga, C. Mwandawiro and N. Minakawa (2014): Preventive effect of permethrin-impregnated long-lasting insecticidal nets on the blood feeding of three major pyrethroid-resistant malaria vectors in western Kenya. Parasit. Vect. 7: 383. PDF 

68. Kawada, H., G. O. Dida, K. Ohashi, E. Kawashima, G. Sonye, S. M. Njenga, C. Mwandawiro and N. Minakawa (2014):  A small-scale field trial of pyriproxyfen-impregnated bed nets against pyrethroid-resistant Anopheles gambiae s.s. in western Kenya. PLoS One 9:e111195. PDF

69. Ohashi, K., Y. Tsuda, D. Kasai, H. Kawada and M. Takagi (2014): Hybridization between sympatric populations of Culex pipiens pallens and Culex pipiens f. molestus (Diptera: Culicidae) in Nagasaki, Japan. Med. Entomol. Zool. 65:67-72. PDF

70. Tsurukawa, C. and H. Kawada (2014): Experiment on mosquito blood feeding using the artificial feeding device. Med. Entomol. Zool. 65: 151-155. PDF

71. Ohba, S., T. T. H. Trang, H. Kawada, L. L. Loan, H. T. Ngoc, S. L. Hoang and M. Takagi (2015): The effect of Olyset® Net to the mosquito larvae and their Heteroptera predators in water jars in southern Vietnam. Jpn. J. Infect. Dis. 69: 262-265. PDF

72. Kawada, H., Y. Higa, K. Futami, Y. Muranami, E. Kawashima, J.H.N. Osei, K.Y. Sakyi, S. Dadzie, D.K. de Souza, M. Appawu, N. Ohta, T. Suzuki, N. Minakawa (2016): Discovery of point mutations in the voltage-gated sodium channel from African Aedes aegypti populations: Potential phylogenetic reasons for gene introgression. PLoS Negl. Trop. Dis. 10: e0004780. PDF

73. Sumita, Y., H. Kawada, and N. Minakawa (2016): Mode of entry of the vaporized knockdown agent pyrethroid into the body of housefly, Musca domestica (Diptera: Muscidae). Appl. Entomol. Zool. 51: 653-659. PDF

74. Kawada, H. (2017): Possible New Controlling Measures for the Pyrethroid-Resistant Malalia Vectors. Ann. Community Med. Pract. 3: 1019. PDF

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