Publications

 



2020 (to March)


  1. 1.J Tang, TJ Templeton, J Cao, R Culleton The consequences of mixed-species malaria parasite co-infections in mice and mosquitoes for disease severity, parasite fitness, and transmission success Frontiers in Immunology 10, 3072


2019


  1. 2.A Ramaprasad, AK Subudhi, R Culleton, A Pain A fast and cost-effective microsampling protocol incorporating reduced animal usage for time-series transcriptomics in rodent malaria parasites Malaria Journal 18 (1), 26


  1. 3.Amit Subudhi, Aidan John O'Donnell, Abhinay Ramaprasad, Hussein M Abkallo, Abhinav Kaushik, Hifzur Rahman Ansari, Alyaa M Abdel-Haleem, Fathia Ben Rached, Osamu Kaneko, Richard Culleton, Sarah E Reece, Arnab Pain Disruption of the coordination between host circadian rhythms and malaria parasite development alters the duration of the intraerythrocytic cycle bioRxiv, 791046


  1. 4.LU Feng, HE Xin-Long, C Richard, CAO Jun A brief history of artemisinin: Modes of action and mechanisms of resistance Chinese journal of natural medicines 17 (5), 331-336


  1. 5.Tobias Mourier, Denise Anete Madureira de Alvarenga, Abhinav Kaushik, Anielle de Pina-Costa, Francisco J Guzmán-Vega, Olga Douvropoulou, Qingtian Guan, Sarah Forrester, Filipe Vieira Santos de Abreu, Cesare Bianco Júnior, Julio Cesar de Souza Junior, Zelinda Maria Braga Hirano, Alcides Pissinatti, Silvia Bahadian Moreira, Maria de Fátima Ferreira-da-Cruz, Ricardo Lourenço de Oliveira, Stefan T Arold, Daniel C Jeffares, Patrícia Brasil, Cristiana Ferreira Alves de Brito, Richard Culleton, Claudio Tadeu Daniel-Ribeiro, Arnab PainThe genome of the zoonotic malaria parasite Plasmodium simium reveals adaptions to host-switching bioRxiv, 841171


2018


  1. 6.Ernest M, Hunja C, Arakura Y, Haraga Y, Abkallo HM, Zeng W, Jackson DC, Chua B, Culleton R The Toll-Like Receptor 2 agonist PEG-Pam2Cys as an immunochemoprophylactic and immunochemotherapeutic against the liver and transmission stages of malaria parasites International Journal for Parasitology: Drugs and Drug Resistance 8 (3) 451-458 2018


  1. 7.Pongvongsa T, Culleton R, Ha H, Thanh L, Phongmany P, Marchand RP, Kawai S, Moji K, Nakazawa S, Maeno Y, Human infection with Plasmodium knowlesi on the Laos-Vietnam border Tropical Medicine and Health 46:33 2018


  1. 8.Lloyd YM, Esemu LF, Antallan J, Thomas B, Yunga ST, Obase B, Christine N, Leke RGF, Culleton R, Mfuh KO, Taylor DW, Improved sensitivity of PCR-based detection of Plasmodium falciparum in saliva using mitochondrial Cox3 and varATS primers Tropical Medicine and Health 46: 22 2018


  1. 9.Tantiamornkul K, Pumpaibool T, Piriyapongsa J, Culleton R*, Lek-Uthai U*; The prevalence of molecular markers of drug resistance in Plasmodium vivax from the border regions of Thailand in 2008 and 2014 International Journal for Parasitology: Drugs and Drug Resistance 8 (2), 229-237 2018


  1. 10.Alvarenga DA*, Culleton R*, Pina-Costa Ad, Rodrigues D, Junior CB, Silva S, Nunes AJ, J Souza jr JCd, Hirano Z, Moreira ZB, Pissinatti A, Abreu F, Areas AL, Lourenço-de-Oliveira R, Zalis MG, Brasil P, Ferreira-da-Cruz MdF, Daniel-Ribeiro CT, Alves de Brito CF, An assay for the identification of Plasmodium simium infection for diagnosis of zoonotic malaria in the Brazilian Atlantic Forest. Scientific Reports 2018 Jan 8;8(1):86 2018


  1. 11.Moriyasu T, Nakamura R, Deloer S, Senba M, Kubo M, Inoue M, Culleton R* & Hamano S*, Schistosoma mansoni infection suppresses the growth of Plasmodium yoelii parasites in the liver and reduces gametocyte infectivity to mosquitoes PLoS Neglected Tropical Diseases 12 (1) 2018



2017


  1. 12.Lu F, Culleton R, Cao J, Artemisinin-Resistant Plasmodium falciparum in Africa, New England Journal of Medicine 20;377(3):306 2017


  1. 13.Abkallo H, Martinelli A, Inoue M, Ramaprasad A, Xangsayarath P, Gitaka J, Tang J, Yahata K, Zoungrana A, Mitaka H, Hunt P, Carter R, Kaneko O, Mustonen V, Illingworth CJR, Pain A & Culleton R, Rapid Identification of Genes Controlling Virulence and Immunity in Malaria Parasites. PLoS Pathogens, 13(7): e1006447  2017


  1. 14. Brasil P, Zalis M G, de Pina-Costa A, Siqueira A M, Bianco Junior C, Silva S, Areas A L L, Pelajo-Machado M, de Alvarenga D A M, Santelli A C F d S, Albuquerque H G, Cravo P, de Abreu F V S, Peterka C L, Zanini G M, Suarez-Mutis M C, Pissinatti A, Lourenco-de-Oliveira R, Brito C F A d, Ferreira-da-Cruz M d F, Culleton R, Daniel-Ribeiro C T Outbreak of human malaria caused by Plasmodium simium in the Atlantic Forest in Rio de Janeiro: a molecular epidemiological investigation. The Lancet Global Health 5: e1038–46 2017


  1. 15. Feng Lu, Meihua Zhang, Richard L. Culleton, Sui Xu, Jianxia Tang, Huayun Zhou, Guoding Zhu, Yaping Gu, Chao Zhang, Yaobao Liu, Weiming Wang, Yuanyuan Cao, Julin Li, Xinlong He, Jun Cao
    and Qi Gao, Return of chloroquine sensitivity to Africa? Surveillance of African Plasmodium falciparum chloroquine resistance through malaria imported to China Parasites & Vectors 10 (1), 355 2017


  1. 16. Maeno Y, Quang NT, Culleton R,  Kawai S, Masuda G, Hori K, Nakazawa S & Marchand, RP Detection of the Plasmodium falciparum Kelch-13 gene P553L mutation in sporozoites isolated from mosquito salivary glands in Southcentral Vietnam. Parasites and Vectors 10 (1), 308 2017


  1. 17. Lu F, Culleton R, Zhang M, Ramaprasad A, von Seidlein L, Zhou H, Zhu G, Tang J, Liu Y, Wang W, Cao Y, Xu S, Gu Y, Li J, Zhang C, Gao Q, Menard D, Pain A, Yang H, Zhang Q & Cao J., Emergence of Indigenous Artemisinin Resistant Plasmodium falciparum in Africa, New England Journal of Medicine 2017; 376:991-993 2017


  1. 18. Y Maeno, R Culleton, N T Quang, S. Kawai, R P Marchand, S Nakazawa, Plasmodium knowlesi and human malaria parasites in Khan Phu, Vietnam: Gametocyte production in humans and frequent co-infection of mosquitoes. Parasitology 144:4 527-535.  2017



2016


  1. 19. Martinelli A & Culleton R. Non-human Primate Malaria Parasites: Out of the forest and into the laboratory Parasitology Oct 17:1-14. 2016


  1. 20. Mulenge F, Hunja C, Magiri E, Culleton R, Kaneko A and Aman  R. Genetic Diversity And Population Structure Of Plasmodium Falciparum In Lake Victoria Islands, A Region Of Intense Transmission.  American Journal of Tropical Medicine & Hygiene 16-0383  2016


  1. 21. Ansari HA, Templeton JT, Subudhi AK, Ramaprasad A, Tang J, Lu J, Naeem R, Oguike MC, Benavente ED, Clark TG, Sutherland CJ, Barnwell JW, Culleton R, Cao J and Pain A. Genome-scale comparison of expanded gene families in Plasmodium ovale wallikeri and Plasmodium ovale curtisi with Plasmodium malariae and with other Plasmodium species. International Journal for Parasitology 2016 Oct; 46 (11) :685-96 2016


  1. 22. Mita T, Culleton R, Takahashi N, M Nakamura, Tsukahara T, Hunja CW, Win ZZ, Htike WW, Marma AS, Dysoley L, Ndounga M, Dzodzomenyo M, Akhwale WS, Kobayashi J, Uemura H, Kaneko A, Hombhanje F, Ferreira MU, Björkman A, Endo H, Ohashi J. Little polymorphism at the K13 propeller locus in worldwide Plasmodium falciparum populations prior to the introduction of artemisinin combination therapies. Antimicrobial agents and chemotherapy 60 (6), 3340-3347 2016



2015


  1. 23. Maeno Y, Quang N T, Culleton R, Kawai S, Masuda G, Nakazawa S, Marchand R; Humans frequently exposed to a range of non-human primate malaria parasite species through the bites of Anopheles dirus mosquitoes in South-central Vietnam Parasites & Vectors 8:376 2015


  1. 24. Tao ZY, Sui Z, Jun C, Culleton R, Fang Q, Xia H, Gao Q; Vector sequence contamination of the Plasmodium vivax sequence database in PlasmoDB and In silico correction of 26 parasite sequences Parasites & Vectors 2015, 8:318 2015


  1. 25. Cravo P, Napolitano H, Culleton R, How genomics is contributing to the fight against artemisinin-resistant malaria parasites, Acta Tropica, 148 1-7 2015


  1. 26. Cox-Singh J & Culleton R, Plasmodium knowlesi: from severe zoonosis to animal model Trends in Parasitology 31-6, 232–238 2015


  1. 27. Abkallo HM, Tangena JA, Tang J, Kobayashi N, Inoue M, Zoungrana A, Colegrave N, Culleton R, Within-host competition does not select for virulence in malaria parasites; studies with Plasmodium yoelii Plos Pathogens 11(2): e1004628 2015


  1. 28. Murai K, Culleton R, Hisaoka T, Endo H, Mita, T Global distribution of polymorphisms associated with delayed Plasmodium falciparum parasite clearance following artemisinin treatment: genotyping of archive blood samples Parasitology International 64 (2015) 267–273  2015


  1. 29. Culleton RL & Abkallo HM, Malaria parasites genetics: doing something useful. Parasitology International 64 (2015) 244–253 2015



2014


  1. 30. Kawai S, Sato M, Kato-Hayashi S, Kishi H, Huffman M, Maeno Y, Culleton R, Nakazawa S, Detection of Plasmodium knowlesi DNA in the urine and faeces of a Japanese macaque (Macaca fuscata) over the course of an experimentally induced infection Malaria Journal 2014, 13:373  2014


  1. 31. Prajapati, SK, Culleton, R., Singh, OMP, Protein trafficking in Plasmodium falciparum infected red cells and impact of the expansion of exported protein families, Parasitology 141 (12) : 1533-1543 2014


  1. 32. Cordina, C., Culleton, R., Jones, B.L., Smith, C., McConnachie, A., Coyne, M and Alexander, C.L Plasmodium knowlesi: Clinical Presentation and Laboratory Diagnosis of the First Human Case in a Scottish Traveller, Journal of Travel Medicine 21(5):357-60 2014


  1. 33. Abkallo HM, Liu W, Hokama S, Ferreira PE, Nakazawa S, Maeno, Y., Quang, N. T., Kaneko, O., Huffman, M.A., Kawai, S., Marchand, R. P., Carter, R., B.H., Hahn and Culleton, R. DNA from Pre-Erythrocytic Stage Malaria Parasites is Detectable by PCR in the Faeces and Blood of Hosts. International Journal For Parasitology 44 (7) : 467-73 2014


  1. 34. Liu, W., Li, Y., Shaw, K. S., Learn, G. H., Plenderleith, L. J., Malenke, J. A., Sundararaman, S. A., Ramirez, M. A., Crystal, P. A., Smith, A. G., Bibollet-Ruche, F., Ayouba, A., Locatelli, S., Esteban, A., Mouacha, F., Guichet, E., Butel, C., Ahuka-Mundeke, S., Inogwabini, B. I., Ndjango, J. B., Speede, S., Sanz, C. M., Morgan, D. B., Gonder, M. K., Kranzusch, P. J., Walsh, P. D., Georgiev, A. V., Muller, M. N., Piel, A. K., Stewart, F. A., Wilson, M. L., Pusey, A. E., Cui, L., Wang, Z., Farnert, A., Sutherland, C. J., Nolder, D., Hart, J. A., Hart, T. B., Bertolani, P., Gillis, A., Lebreton, M., Tafon, B., Kiyang, J., Djoko, C. F., Schneider, B. S., Wolfe, N. D., Mpoudi-Ngole, E., Delaporte, E., Carter, R., Culleton, R. L., Shaw, G. M., Rayner, J. C., Peeters, M., Hahn, B. H. and Sharp, P. M. African origin of the malaria parasite Plasmodium vivax, Nature Communications 5: 3346 2014


  1. 35. Tao Z, Fang Q, Liu X, Culleton R, Xia H, Gao Q,  Congenital Malaria in China, PLOS Neglected Tropical Diseases 8: e2622. 2014



2013


  1. 36. Shimokawa, C., Culleton, R., Imai, T., Suzue, K., Hirai, M., Taniguchi, T., Kobayashi, S., Hisaeda, H., Hamano, S.: Species-specific immunity induced by infection with Entamoeba histolytica and Entamoeba moshkovskii in mice. PLoS ONE 8(11): e82025 2013


  1. 37. Hunja CW, Unger H, Ferreira P, Lumsden R, Morris S,  Aman R, Alexander C, Mita T, Culleton, R Travelers as sentinels: Assaying the worldwide distribution of polymorphisms associated with artemisinin combination therapy resistance in Plasmodium falciparum using malaria cases imported into Scotland. International Journal for Parasitology 43 (11) : 885-9 2013


  1. 38. Ferreira P E, Culleton R, Gil J P, Meshnick S R, Artemisinin resistance in Plasmodium falciparum: What is it really?  Trends in Parasitology Volume 29, Issue 7, Pages 318–320 2013


  1. 39. Bispo N.A., Culleton R, Silva L.A. and Cravo P., A systematic in silico search for target similarity identifies several approved drugs with potential activity against the Plasmodium falciparum apicoplast, PLoS ONE 8(3): e59288 2013



2012


  1. 40. Zhao H, Konishi A, Fujita Y, Yagi M, Ohata K, Aoshi T, Itagaki S, Sato S, Narita H, Abdelgelil N, Inoue M, Culleton R, Kaneko O, Nakagawa A, Horii T, Akira S, Ishii KJ, Coban C, Lipocalin 2 Bolsters Innate and Adaptive Immune Responses to Blood-Stage Malaria Infection by Reinforcing Host Iron Metabolism, Cell Host & Microbe, Vol. 12, Issue 5, pp. 705-716, 15 November 2012


  1. 41. Yahata K, Treeck M, Culleton R, Gilberger TW, Kaneko O. Time-lapse imaging of red blood cell invasion by the rodent malaria parasite Plasmodium yoelii. PLoS ONE 7(12): e50780 2012


  1. 42. Culleton R & Carter R, African Plasmodium vivax: Distribution and origins  International Journal for Parasitology, 42 (12) 1091–1097, November 2012


  1. 43. Inoue M, Tang, J, Miyakoda M, Kaneko O, Yui K & Culleton R, The species specificity of immunity generated by live whole organism immunization with erythrocytic and pre-erythrocytic stages of rodent malaria parasites and implications for vaccine development. International Journal for Parasitology 42 (9)  859–870 August 2012


  1. 44. Culleton R & Ferreira P, Duffy Phenotype and Plasmodium vivax infections in Humans and Apes, Africa. Emerging Infectious Diseases Vol. 18, No. 10, October 2012


  1. 45. Tang J, Dai Y, Zhang H, Culleton RL, Liu Y, Zhao S, Wang X, Guan X, Kaneko O, Zhu Y. Positive diversifying selection on Plasmodium vivax RON2 protein. Parasitology Feb 10:1-7. 2012


  1. 46. Ferreira P & Culleton R, Dynamics of Plasmodium falciparum selection after artemether-lumefantrine treatment in Africa. Journal of Infectious Diseases Mar 28 2012


  1. 47. Culleton R & Carter R, Genetic Mapping of Virulence in Rodent Malarias, in "Evolution of Virulence in Eukaryotic Microbes", Editors, L. David Sibley, Barbara J. Howlett, and Joseph Heitman, Wiley-         Blackwell 2012 (book chapter)


  1. 48. Stephens R, Culleton R, Lamb T. The contribution of Plasmodium chabaudi to our understanding of malaria  Trends in Parasitology Feb;28(2):73-82 2012



2011


  1. 49. Culleton R, Coban C, Zeyrek FY, Cravo P, Kaneko A, Randrianarivelojosia M, Andrianaranjaka V, Kano S, Farnert A, Arez AP,  Sharp PM, Carter R & Tanabe K, The origins of African Plasmodium vivax; insights from mitochondrial genome sequencing, PLoS ONE 6(12): e29137 2011


  1. 50. Sungkapong T, Culleton R, Yahata K, Tachibana M, Ruengveerayuth R, Udomsangpetch R, Torii M, Tsuboi T, Sattabongkot J, Kaneko O, Chotivanich K. Humoral immune responses to Plasmodium vivax subtelomeric transmembrane proteins in Thailand. The Southeast Asian Journal of Tropical Medicine and Public Health 42(6), 1313  2011


  1. 51. Mita T, Venkatesan M, Ohashi J, Culleton R, Takahashi N, Tsukahara T, Ndounga M, Dysoley L, Endo H, Hombhanje F, Ferreira M, Plowe CV, Tanabe K Limited geographical origin and global spread of sulfadoxine-resistant dhps alleles in Plasmodium falciparum populations Journal of Infectious Diseases (2011) 204 (12): 1980-1988. 2011


  1. 52. Tsumori Y,  Ndounga M, Sunahara T, Hayashida N, Inoue M, Nakazawa S, Casimiro P. N, Isozumi R, Uemura H,  Tanabe K, Kaneko O, Culleton R L Plasmodium falciparum: differential selection of drug resistance alleles in contiguous urban and peri-urban areas of Brazzaville, Republic of Congo PLoS ONE 6(8): e23430 2011


  1. 53. Zhi-Yong Tao , Hua-Yun Zhou , Hui Xia , Sui Xu , Han-Wu Zhu , Richard L. Culleton , Eun-Taek Han , Feng Lu , Qiang Fang , Ya-Ping Gu , Yao-Bao Liu , Guo-Ding Zhu , Wei-Ming Wang , Ju-Lin Li , Jun Cao  and Qi Gao Adaptation of a visualized loop-mediated isothermal amplification technique for field detection of Plasmodium vivax infection Parasites & Vectors 2011, 4:115 2011


  1. 54. Marchand R P, Culleton, R, Maeno, Y, Quang, N T, Nakazawa, S. Co-infections involving Plasmodium knowlesi, P. falciparum and P. vivax are common among malaria infected humans and Anopheles dirus in Khanh Phu, Vietnam Emerging Infectious Diseases, 17:7, 1232:1239 2011


  1. 55. Oguike M, Betson M, Burke M, Nolder D, Stothard R, Kleinschmidt I, Proietti C, Bousema T, Ndounga M, Tanabe K, Ntege E, Culleton R & Sutherland CJ Plasmodium ovale curtisi and Plasmodium ovale wallikeri circulate simultaneously in African communities. International Journal For Parasitology 41. 667-683. 2011


  1. 56. Inoue M & Culleton R. The intradermal route for inoculation of sporozoites of rodent malaria parasites for immunological studies Parasite Immunology. 2011 Jan;33(2):137-142. 2011


  1. 57. Culleton RL, Inoue M, Reece SE, Cheesman S, Carter R. Strain-specific immunity induced by immunization with pre-erythrocytic stages of Plasmodium chabaudi. Parasite Immunology 2011 Jan;33(1):73-8. 2011


  1. 58. Nakazawa S, Culleton R, Maeno Y. In vivo and In vitro gametocyte production of Plasmodium falciparum isolates from Northern Thailand.  International Journal for Parasitology Mar;41(3-4):317-23 2011



Pre-2011 (non-Malaria Unit)


  1. 59. Culleton R, Kaneko O. Erythrocyte binding ligands in malaria parasites: intracellular trafficking and parasite virulence. Acta Tropica Jun;114(3):131-7. 2010


  1. 60. Pattaradilokrat S, Culleton R, Cheesman S, Carter R. Gene encoding erythrocyte binding ligand linked to blood stage multiplication rate phenotype in Plasmodium yoelii yoelii. Proceedings of the National Academy of Sciences of the U.S.A. Apr;106(17):7161-6. 2009


  1. 61. Nakazawa S, Marchand R, Quang N, Culleton R, Manh N, Maeno Y. Anopheles dirus co-infection with human and monkey malaria parasites in Vietnam. International Journal for Parasitology Dec;39(14): 533-7 2009


  1. 62. Mita T, Tanabe K, Takahashi N, Culleton R, Ndounga M, Dzodzomenyo M, Akhwale W S, Kaneko A & Kobayakawa T. Indigenous evolution of Plasmodium falciparum pyrimethamine resistance multiple times in Africa. Journal of Antimicrobial Chemotherapy Feb;63(2):252-5. 2009


  1. 63. Culleton R, Ndounga M, Zeyrek F, Coban C, Casimiro P, Takeo S, Tsuboi T, Yadava A, Carter R & Tanabe K. Evidence for the transmission of Plasmodium vivax in the Republic of the Congo, West Central Africa. Journal of Infectious Diseases. Nov;200(9):1465-9. 2009


  1. 64. Hayakawa T, Culleton R, Otani H, Horii T, Tanabe K. Big bang in the evolution of extant malaria parasites. Molecular Biology and Evolution. Oct;25(10):2233-9. 2008


  1. 65. Culleton R, Mita T, Ndounga M, Unger H, Cravo P, Paganotti G, Takahashi N, Kaneko A, Eto H, Tinto H, Karema C, D'Alessandro U, do Rosario V, Kobayakawa T, Ntoumi F, Carter R, Tanabe K. Failure to detect Plasmodium vivax in West and Central Africa by PCR species typing. Malaria Journal; 7:174. 2008


  1. 66. Tanabe K, Escalante A, Sakihama N, Honda M, Arisue N, Horii T, Culleton R , Hayakawa T, Hashimoto T, Longacre S, Pathirana S, Handunnetti S, Kishino H. Recent independent evolution of msp1 polymorphism in Plasmodium vivax and related simian malaria parasites. Molecular and  Biochemical Parasitology. Nov;156(1):74-9 2007


  1. 67. Hunt P, Afonso A, Creasey A, Culleton R, Sidhu A, Logan J, McNae I, do Rosario V, Fidock D, Carter R & Cravo P. Gene encoding a deubiquitinating enzyme is mutated in artesunate- and chloroquine-resistant rodent malaria parasites. Molecular Microbiology Jul;65(1):27-40 2007


  1. 68. Cravo P CR, Culleton R, Afonso A, Ferreira I, do Rosario V. Mechanisms of drug resistance in malaria: current and new challenges. Anti-infective Agents in Medicinal Chemistry. 2006;5 (January):63-73. 2006


  1. 69. Martinelli A, Cheesman S, Hunt P, Culleton R, Raza A, Mackinnon M & Carter R.A genetic approach to the de novo identification of targets of strain specific immunity in Plasmodium chabaudi. Proceedings of the National Academy of Sciences of the U.S.A. Jan;102(3):814-9. 2005


  1. 70. Culleton R, Martinelli A, Hunt P, Carter R. Linkage group selection: rapid gene discovery in malaria parasites. Genome Research Jan;15(1):92-7. 2005


  1. 71. de Roode J, Culleton R, Cheesman S, Carter R, Read A. Host heterogeneity is a determinant of competitive exclusion or coexistence in genetically diverse malaria infections. Proceedings of the Royal Society B Biological Sciences May;271(1543):1073-80 2004


  1. 72. de Roode J, Culleton R, Bell A, Read A. Competitive release of drug resistance following drug treatment of mixed Plasmodium chabaudi infections. Malaria Journal Sep;3:33. 2004


  1. 73. Cravo P, Culleton R, Hunt P, Walliker D, Mackinnon M. Antimalarial drugs clear resistant parasites from partially immune hosts. Antimicrobial Agents and Chemotherapy Oct;45(10): 2897-901. 2001