2012年

Nguyen Tien Huy, Tran Thi Ngoc Ha, Lyre Anni Murao, Nguyen Thi Phuong Lan, Tran Thi Thuy, Ha Manh Tuan, Cao Thi Phi Nga, Vo Van Tuong, Tran Van Dat, Mihoko Kikuchi, Michio Yasunami, Kouichi Morita, Vu Thi Que Huong, Kenji Hirayam; Cell-free Circulating DNA: a Novel Biomarker in Dengue Virus Infection. Asian-African Research Forum on Emerging and Reemerging Infections 2012., Date January 11 Wed. to 12 Thu., 2012., Venue Kobe International Conference Center (Asian-African Research Forum on Emerging and Reemerging Infections 2012, Date January 11 Wed. to 12 Thu., 2012., Venue Kobe International Conference Center, Ministry of Education, Culture, Spots, Science and Technology (MEXT), Japan Initiative for Global Research Network on Infectious Diseases(J-GRID), p142.)

Mahamoud Sama Cherif, Mohammed Nasir Shuaibu, 黒崎友亮子、児玉幸修、Helegbe Gideon K,　菊池三穂子、柳　哲雄、坪井敬文、佐々木均、由井克之、平山謙二： Nanoparticle coated PyMSP-1 plasmid engages CD40 on DCs to produce high levels of IL-12. 第８１回日本寄生虫学会大会、平成２４年３月２３日ー２４日、兵庫医科大学西宮キャンパス、神戸、兵庫県　（第８１回日本寄生虫学会大会　プログラム集・抄録集, pp73, 2012)

Bao Quoc Lam, Huy Tien Nguyen, 柳　哲雄、千葉正親、Mohammed Nasir Shuaibu, 菊池三穂子. Experimental rodent model of cerebral malaria resistance in semi-immune. 第８１回日本寄生虫学会大会、平成２４年３月２３日ー２４日、兵庫医科大学西宮キャンパス、神戸、兵庫県　（第８１回日本寄生虫学会大会　プログラム集・抄録集, pp75, 2012)

Mbanefo C. Evaristus, 余　伝信、菊池三穂子、Mohammed Nasir Shuaibu, Daniel Boamah, 桐木　雅史、林直子、長田良雄、千種雄一、濱野真二郎、平山謙二. Origin of novel protein-coding genes with similar signal sequence in Schistosoma japonicum. 第８１回日本寄生虫学会大会、平成２４年３月２３日ー２４日、兵庫医科大学西宮キャンパス、神戸、兵庫県. （第８１回日本寄生虫学会大会　プログラム集・抄録集, pp56, 2012)

橘 裕司, 柳 哲雄,小林正規、平山謙二、Rajapakse R.P.V. Jayanthe: 野生のトクザルから分離したEntamoeba nuttailiの性状解析。第８１回日本寄生虫学会大会、平成２４年３月２３日ー２４日、兵庫医科大学西宮キャンパス、神戸、兵庫県（第８１回日本寄生虫学会大会　プログラム集・抄録集, pp88, 2012)

Daniel Boamah, 菊池三穂子、 チェン　ホンゲン、平山謙二 ：Immunopreteomics Identification of major IgE and Ig4-specific Schistosoma japonicum antigens using infected human serum. 第８１回日本寄生虫学会大会、平成２４年３月２３日ー２４日、兵庫医科大学西宮キャンパス、神戸、兵庫県. （第８１回日本寄生虫学会大会　プログラム集・抄録集, pp69, 2012)

Omar AH: Toll-like receptor 9 (TLR9) polymorphism associated with symptomatic malaria: a cohort study. MOLECULAR IMMUNOLOGY & IMMUNOGENETICS CONGRESS 2012 (MIMIC 2012) , April 27-29, 2012, Papillon Ayscha, Antalya, Turkey

Juntra Karbwang and Kenji Hirayama： Provisional Study for establishing a new platform for the clinical Product development. Double blinded randomised placebo controlled phase II trial of Shiunko Ointment in Ethiopian patients with localized cutaneous Leishmaniasis. GCOE Research in Progress Seminar, Ryojyun Hall Nagasaki University, April 24, Tue, 2012

平山謙二：　熱帯感染症制御のための医薬品開発研究, 　第82回実験結核研究会, 平成24年5月9日, 広島国際会議場, 広島　（第82回実験結核研究会, 平成24年5月9日, 広島国際会議場, 広島、プログラム、p.15）

Mihoko Kikuchi: Immunogenetic analysis of patients with early onset schistosomal fibrosis in Sorsogon Province, Philippines. The Fifth ASEAN Congress of Tropical Medicine and Parasitology (ACTMP), May 15 to 17, 2012, University of the Philippines, Manila, Philippines.

Mihoko Kikuchi, Lydia R. Leonardo, Yuichi Chigusa, Edelwisa M, Segubre-Mercado, Noriko Kobayashi, Naoko Hayashi,Tetsu Inoue, Napoleon L. Arevalo, Ronald R. Lim, Lea M. Agsolid, Ken Agatsuma, Kenji Hirayama.　Immunogenetic analysis of Patients with early onset schistosomal fibrosis in Sorsogon Province, the Philippines．　　Forum Cheju 15, The 15th Japan-Korea Parasitologists' Seminar, Current Trends in Parasitology, Research in Japan and Korea., May 23-25, 2012, Miyazaki Aoshima Palm Beach Hoel, Aoshima, Miyazaki, Japan 　(Forum Cheju 15, The 15th Japan-Korea Parasitologists' Seminar, Current Trends in Parasitology, Research in Japan and Korea., May 23-25, 2012, Miyazaki Aoshima Palm Beach Hoel, Aoshima, Miyazaki, Japan, Program, PP-10)

平山謙二：新たなＤＤＳと組み合わせたＤＮＡワクチンの開発．　先端創薬シンポジウムin長崎大学～挑戦：長崎から世界へ～。平成24年7月12日、長崎大学薬学部第二講義室

Lan Nguyen Thi Phuong, Thuong Van Nguyen, Thanh Le Chi, Thang Minh Cao, Nhon Cao Thi My, Truong Quang Nguyen, Ngu Vu Thien Thu, Quoc Kien Do, Ha Tran Thi Ngoc, Huy Tien Nguyen, Phuong Thi Pham, Ton Tran, Mihoko Kikuchi, Quang Chan Luong, An Van Tran, Huong Vu Thi Que, Kenji Hirayama; 　T cell subsets dynamics in the course of acute dengue infection. Symposium for Interim Evaluation on the ”Collaborative Study on Emerging and Re-emerging Infectious Diseases in Viet Nam: Enhancement of Research Capacity Phase II, 2011-2015” Project., NIHE, Hanoi, Viet Nam, 27th August 2012. ( Symposium for Interim Evaluation on the ”Collaborative Study on Emerging and Re-emerging Infectious Diseases in Viet Nam: Enhancement of Research Capacity Phase II, 2011-2015” Project. 27th August 2012. Abastract, pp11.)

橘 裕司, 柳 哲雄, Basu Pandey, Kishor Pandey, Chaturong Putaporntip, Somchai Jongwutiwes, 平山謙二, ネパールのカトマンズにおける腸管寄生アメーバ感染の疫学研究, 第53回日本熱帯医学会大会, 2012年9月5日(水)～6日(木),　とかちプラザ, 帯広 (第53回日本熱帯医学会大会, プログラム抄録集、「ワンワールド・ワンヘルス」、pp77)"

Kenji Hirayama, Evaristus C. Mbanefo, Yu Chuanxin, Mihoko Kikuchi, Mohammed N. Shuaibu, Masachika Senba, Yuichi Chigusa, Yoshio Osada. Origin and molecular characterization of a novel protein family with SEA-like domain in Schistosoma japonicum. 第53回日本熱帯医学会大会, 2012年9月5日(水)～6日(木),　とかちプラザ, 帯広 (第53回日本熱帯医学会大会, プログラム抄録集、「ワンワールド・ワンヘルス」、pp61)

Nguyen Tien Huy, Tran Van Giang, Dinh Ha Duy Thuy, Mihoko Kikuchi, Tran Tinh Hien, Javier Zamora and Kenji Hirayama．Meta-analysis of Factors Associated with Dengue Shock Syndrome．　　第53回日本熱帯医学会大会, 2012年9月5日(水)～6日(木),　とかちプラザ, 帯広 (第53回日本熱帯医学会大会, プログラム抄録集、「ワンワールド・ワンヘルス」、pp49、2012)

Shuaibu MN, Cherif MS, Kurosaki T, Kodama Y, Helegbe GK, Kikuchi M, Yanagi T, Tsuboi T, Sasaki H, Hirayama K.　Improved immunogenicity of nanoparticle-coated PyMSP-1 C-terminus DNA vaccine using different routes of administration．　第53回日本熱帯医学会大会, 2012年9月5日(水)～6日(木),　とかちプラザ, 帯広 (第53回日本熱帯医学会大会, プログラム抄録集、「ワンワールド・ワンヘルス」、pp41)

Mihoko Kikuchi, Natasha Andrea Fernandez, Lydia R. Leonardo, Yuichi Chigusa, Naoko Hayashi,Tetsu Inoue, Napoleon L. Arevalo, Ronald R. Lim, Lea M. Agsolid, James Chua, Ken Agatsuma, Kenji Hirayama.　Surveillance on for schistosomal fibrosis in Sorsogon Province, the Philippines．第53回日本熱帯医学会大会, 2012年9月5日(水)～6日(木),　とかちプラザ, 帯広 (第53回日本熱帯医学会大会, プログラム抄録集、「ワンワールド・ワンヘルス」、pp60)

渡邊直熙、古田隆久、平山謙二, マラリアとデング熱におけるマスト細胞由来VEGF。 第40回日本臨床免疫学会総会、　2012.09.27（木）-29（土）、京王プラザホテル, 東京

"菊池三穂子, Lydia R. Leonardo, 千種雄一, Edelwisa M. Segubre-Mercado, 小林典子, 林尚子, Napoleon L. Arevalo, Ronald R. Lim, Lea M. Agsolid, 我妻健, 平山謙二.　　フィリピンの若年性住血吸虫性肝線維症とHLA-DRB1*15:01との相関. 第21回日本組織適合性学会大会, 平成２４年 ９月15日-17日 、明治大学駿河台キャンパス　リバティホール、東京 (日本組織適合性学会誌 MHC Vol. 19 No. 2, 2012、pp89, 2012）

平山 謙二: 熱帯感染症とHLA. 第21回日本組織適合性学会大会, 平成２４年 ９月15日-17日 、明治大学駿河台キャンパス　リバティホール、東京 (日本組織適合性学会誌 MHC Vol. 19 No. 2, 2012、pp61, 2012）

Florencia Del Puerto Rodas, Eiki J. Nishizawa, 菊池三穂子, Yelin Roca, Luis A. Renjel,　小宮憲洋、前村浩二、平山謙二: V281L of the CYP21 gene causing 21-Hydroxylase deficiency located in the class III region of resistant HLA haplotype in the chronic Chagas disease. 第21回日本組織適合性学会大会, 平成２４年 ９月15日-17日 、明治大学駿河台キャンパス　リバティホール、東京 (日本組織適合性学会誌 MHC Vol. 19 No. 2, 2012、pp106, 2012）

平山謙二：漢方製剤の国際化と紫雲膏プロジェクト ―エチオピアでの皮膚リーシュマニア症に対する紫雲膏の有効性に関する臨床試験。　日本生薬学会第59回年会　千葉２０１２　ワークショップ「生薬・漢方製剤の国際化」、2012年9月17日（月），18日（火）、かずさアカデミアパーク、千葉県木更津市 （日本生薬学会第59回年会　講演要旨集　千葉２０１２、2012年9月17日（月），18日（火）、かずさアカデミアパーク、pp.30-31）

Daniel Boamah, Mihoko Kikuchi, Ngyen Tien Huy, Kenta Okamoto, Honggen Chen, Irene Ayi, Daniel Adjei Boakye,Kwabene Mante Bosompem, Kenji Hirayama, Immunopreteomics Identification of Major IgE and Ig4 Reactive Schistosoma japonicum Adult Worm Antigens Using Chronically Infected Human Plasma, HUPO 11th Annual Would Congress, September 9-13, 2012, Hynes Convention Center, Boston, Massachusetts, USA. HUPO 11th Annual Would Congress, September 9-13, 2012, Boston, Massachusetts, Abstract, pp76）

Helegbe GK, Yanagi T, Shuaibu MN, Kikuchi M, Cherif MS and Hirayama K., Anti-EPO antibodies levels varies in different strains of semi-immune mice infected with Plasmodium berghei ANKA. XVIII International congress for Tropical medicine and malaria and XLVIII congress of the Brazilian Society of Tropical medicine. September 23-27, 2012. Rio de Janeiro, Brazil.

平山 謙二: 淘汰圧としての熱帯感染症, シンポジウム7　感染症の遺伝学：ゲノムと環境の相互作用 日本人類遺伝学会第57回大会　平成24年10月24日ー27日、京王プラザホテル、東京都　(日本人類遺伝学会第57回大会　解析から応用へ、そして未来への飛躍　プログラム、ｐｐ110、2012)

Mahamoud Sama Cherif, Mohammed Nasir Shuaibu, Tomoaki Kurosaki, Yukinobu Kodama, Gideon Kofi Helegbe, Mihoko Kikuchi, Tetsuo Yanagi, Takafumi Tsuboi, Histoshi Sasaki, Katsuyuki Yui, Kenji Hirayama, Differential activation of dendritic cells by nanoparticle-coated DNA vaccines using different route of delivery. 61st ASTMH Annual Meeting, November 11-15 2012, Atlanta Marriott Marquis, Hilton Atlanta, Atlanta GA, USA. (Am J Trop Med Hyg, Vol. 87 November 2012 Number 5 Supplement; American Society of Tropical Medicine and Hygiene 61st Annual Meeting Program:168.)

Evaristus C. Mbanefo, Yu Chuanxin, Mihoko Kikuchi, Mohammed N. Shuaibu, Daniel Boamah, Masashi Kirinoki, Naoko Hayashi, Yuichi Chigusa, Yoshio Osada, Shinjiro Hamano and Kenji Hirayama. Origin, Diversity and Molecular characterization of a Novel Protein-Coding Gene Family with Similar Signal Sequence in Schistosoma japonicum. 61st ASTMH Annual Meeting, November 11-15 2012, Atlanta Marriott Marquis, Hilton Atlanta, Atlanta GA, USA. (Am J Trop Med Hyg, Vol. 87 November 2012 Number 5 Supplement; American Society of Tropical Medicine and Hygiene 61st Annual Meeting Program:526）

Nguyen Tien Huy, Nguyen Thanh Hong Thao, Tran Thi Ngoc Ha, Nguyen Thi Phuong Lan, Tran Thi Thuy, Ha Manh Tuan, Cao Thi Phi Nga, Vo Van Tuong, Tran Van Dat, Mihoko Kikuchi, Vu Thi Que Huong, and Kenji Hirayama. Clinical rule to predict recurrent shock in dengue shock syndrome. 61st ASTMH Annual Meeting, November 11-15 2012, Atlanta Marriott Marquis, Hilton Atlanta, Atlanta GA, USA. (Am J Trop Med Hyg, Vol. 87 November 2012 Number 5 Supplement; American Society of Tropical Medicine and Hygiene 61st Annual Meeting Program:637)

Mohammed Nasir Shuaibu, Sama M. Cherif, Tomoaki Kurosaki, Yukinobu Kodama, Mihoko Kikuchi, Tetsuo Yanagi, Hitoshi Sasaki, Kenji Hirayama. Augmented Protective Effect of Nanoparticle-coated PYGPI8p-related transamidase in mouse model. 61st ASTMH Annual Meeting, November 11-15 2012, Atlanta Marriott Marquis, Hilton Atlanta, Atlanta GA, USA. (Am J Trop Med Hyg, Vol. 87 November 2012 Number 5 Supplement; American Society of Tropical Medicine and Hygiene 61st Annual Meeting Program :LB-52)

Mahamoud Sama Cherif, Mohammed Nasir Shuaibu, Tomoaki Kurosaki, Yukinobu Kodama, Gideon Kofi Helegbe, Mihoko Kikuchi, Tetsuo Yanagi, Takafumi Tsuboi, Histoshi Sasaki, Katsuyuki Yui, Kenji Hirayama, Differential activation of dendritic cells by nanoparticle-coated malaria blood-stage DNA vaccines, 第41回日本免疫学会学術集会, 2012年12月5日(水)-7日(金,), 神戸国際会議場, 神戸 （2012　日本免疫学会総会・学術集会記録　４１巻、Proceddings of the Japanese Society for Immunology (JSI) Vol.41, 2012, ISSN 0919-1984, pp206.）

Hirayama K, Shuaibu MN, Cherif MS, Kurosaki T, Kodama K, Tsuboi T, Helegbe G, Kikuchi M, Yanagi T, Yui K. and Sasaki H ：Novel malaria vaccine candidate PyTAM (Plusmodium yoelii GPI8p-transamidase related protein) confirmed by NANOBALL vaccine delivery system. The 6th Nagasaki Symposium on Tropical and Emerging Infectious Diseases & The 11th Nagasaki-Singapore Medical Symposium, Ryojun Auditorium Nagasaki University, Sakamoto campus, Nagasaki, Japan, December 10 (Mon)～12(Wed), 2012. (The 6th Nagasaki Symposium on Tropical and Emerging Infectious Diseases & The 11th Nagasaki-Singapore Medical Symposium, December 10 (Mon)～12(Wed), 2012, Ryojun Auditorium Nagasaki University, Sakamoto campus, Nagasaki, Japan, Abstract pp.22)

Lam Quoc Bao, Nguyen Tien Huy, Mihoko Kikuchi, Tetsuo Yanagi, Masachika Senba, Mohammed Nasir Shuaibu, Kiri Honma, Katsuyuki Yui, Kenji Hirayama ：CD19(＋) B cells Confer Protection Against Experimental Cerebral Malaria in Semi−immune Rodent Model. The 6th Nagasaki Symposium on Tropical and Emerging Infectious Diseases & The 11th Nagasaki-Singapore Medical Symposium, Ryojun Auditorium Nagasaki University, Sakamoto campus, Nagasaki, Japan, December 10 (Mon)～12(Wed), 2012. (The 6th Nagasaki Symposium on Tropical and Emerging Infectious Diseases & The 11th Nagasaki-Singapore Medical Symposium, December 10 (Mon)～12(Wed), 2012, Ryojun Auditorium Nagasaki University, Sakamoto campus, Nagasaki, Japan, Abstract pp.55)

Evaristus C. Mbanefo, YU Chuanxin, Mihoko Kikuchi, Mohammed N. Shuaibu, Daniel Boamah, Masashi Kirinoki, Naoko Hayashi, Yuichi Chigusa, Yoshio Osada, and Kenji Hirayama：Molecular characterization of a Novel Protein−Coding Gene Family with SEA−like Domain in Schistosoma japonicum. The 6th Nagasaki Symposium on Tropical and Emerging Infectious Diseases & The 11th Nagasaki-Singapore Medical Symposium, Ryojun Auditorium Nagasaki University, Sakamoto campus, Nagasaki, Japan, December 10 (Mon)～12(Wed), 2012 (The 6th Nagasaki Symposium on Tropical and Emerging Infectious Diseases & The 11th Nagasaki-Singapore Medical Symposium, December 10 (Mon)～12(Wed), 2012, Ryojun Auditorium Nagasaki University, Sakamoto campus, Nagasaki, Japan, Abstract pp.70)