In December １９７４， Prof. Keizo Matsumoto（imcumbent Emeritus Prof.）arrived as a professor of the Department of Internal Medicine, from when the Ward of Internal Medicine in the University Hospital started its real activities. Since April １９９４， Dr. Tsuyoshi Nagatake has succeeded as a next professor after the retirement of Prof. Keizo Matsumoto. The department is now one of the leading in the field of infectious diseases in the respiratory tract and infectious diseases in the tropical area. Besides lectures and training for medical students we make research on respiratory infections using quantitative culture method with inflammatory cytology of the sputum as well as bronchial secretes taken through bronchofiberscope. Antibiotic concentration in clinical specimens and susceptibility of causative organisms to various drugs are also measured to evaluate efficacy of chemotherapy. Clinical training for a doctor as a trainee is done to make a high quality physician, as not only a specialist for infectious field but a general physician for whole internal medicine.